Basic Information

Insect: Anopheles cruzii
Gene Symbol: -
Assembly: GCA_943734635.1
Location: OX030879.1:48059750-48062104[-]

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 4.3 1.1e+04 -3.6 0.0 20 33 105 121 102 133 0.65

2 10 0.13 3.5e+02 1.2 0.4 6 32 366 395 364 407 0.64

3 10 0.0041 11 6.1 0.0 21 46 493 518 487 524 0.85

4 10 0.00024 0.62 10.0 0.0 21 45 521 545 518 552 0.87

5 10 0.0059 15 5.6 0.1 21 45 549 573 544 578 0.89

6 10 0.17 4.3e+02 0.9 0.1 21 48 601 628 588 633 0.84

7 10 0.00027 0.71 9.8 0.1 22 52 631 661 620 662 0.82

8 10 0.04 1e+02 2.9 0.0 22 45 687 710 684 717 0.84

9 10 7.9e-05 0.2 11.6 0.1 21 48 714 741 709 745 0.86

10 10 0.00036 0.95 9.4 0.0 21 45 742 766 738 772 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	4.3	1.1e+04	-3.6	0.0	20	33	105	121	102	133	0.65
2	10	0.13	3.5e+02	1.2	0.4	6	32	366	395	364	407	0.64
3	10	0.0041	11	6.1	0.0	21	46	493	518	487	524	0.85
4	10	0.00024	0.62	10.0	0.0	21	45	521	545	518	552	0.87
5	10	0.0059	15	5.6	0.1	21	45	549	573	544	578	0.89
6	10	0.17	4.3e+02	0.9	0.1	21	48	601	628	588	633	0.84
7	10	0.00027	0.71	9.8	0.1	22	52	631	661	620	662	0.82
8	10	0.04	1e+02	2.9	0.0	22	45	687	710	684	717	0.84
9	10	7.9e-05	0.2	11.6	0.1	21	48	714	741	709	745	0.86
10	10	0.00036	0.95	9.4	0.0	21	45	742	766	738	772	0.91

Sequence Information

Coding Sequence: ATGCTGGGAAAGTATGGCGACGCGAGTTCCAGCTCGATGATTAACCTGGAAAATGGGCTCCGGAACCGTGTGCTGTACCACCAGAACATGATGGGCATGAATCTGATGGCCGAGTTCTACCACAACCCAACCGGCACCGTTTCCGCATCCGTCGGCGTTGCTACGTCCCACTCACAGAAGATGCTCAACAGTCTGACCGGAAACATACTGGTGCCTGGGGTGCCAAGCAACCACCAACAGCAGCTTCAGCATAGCAACGGTACATCACTAGTAACACTTCCCTTGGGAGCAGCCGCCACCGCCGGAGTAGCTTCATCGCAGCAACCGTTGACGCTGTTTCAGTGTCAAGTCTGTCAGAAAACTTTCCTCTCCAGCACGATGCTGGTCGTGCACATGAAAACTCACGATGCCGATTATGCGGCGCGCGATGAGACCACCGGCGGCTACATGCCACCTTCCGCGATGCCACCTTCGTCTGGAAACGGAACAGGCAGCAAAACTAGTCCCCCGTCGCTACTCACACAGCCCAACATCAAGAGCGAGTACGTGGGGGGCTCCCGGTCCGGTTCGGTACCGCTCCCTGACGGTGGTCACAGCATCTCTGGCCACCACGGTGGTGGTGGTATCGTCAAGCAGTTTGACTGCCACATCTGCCACAAATCTTTCATGACACTGATGAACCTCAATCTCCACATGAAAATTCACGAAAACGAACAAAAAATGACCGCTCACACGTACTCGCAGACGATCGGTGGTGCCGGAAGTGGAGCCAACAGCATAATCGTGGGCTCCAGTGCGCTCAGCTACCAGCATCATCACAGCCACCACGGCCAGCAGCAGCAGCAGCACCACGTGATGGTGGCCACTACTGTCGGAGGCGCCACTACTGCGGTGGCTTCCTTGCCCCCCGAGGGCCTATGTCAAATTTGCCATAAAACGTTCAACAGTACCGAACAATTTACGGCACACATGAAGATGCACGAGGATGAGTTCAAAAATCGGGCTCTTTATCACTCCTCGGTGACGGCGGCGGCACCCGGTGGCAACGCTAACGGGGTTGTACAGCCACCAAACAATCCGTTCACCGGTGGCACCGCGACACACGGACCGTTTACGCCCCACGTGGCGTCGTCGCCGGTGCAACAAGAACCGGCGaaggggcaccgttgtccgatctgtcacaaaatgtccagcaacattatcgagcacatcaagcagcacgaaggtcagctgtcgatgggcggcaccaacggtgcgtccgcttcgcccgaagggagccccaccaccagggggacggataatgccacacccgggtaccagatgaacgaggaatcgcaatcgtcgcagggagatgatagcgagaatggtggcaccgatggcgcgggaaccgatccacggaagcagcacgagtgtttgatttgtcgcaaaaagttctccagctccggcaatctggccatccacatacgcgttcactcgggtgagaaaccgttcaaatgtagcgtgtgcgggaagggttttattcagtcgaataatttggccacgcacatgaaaacgcatacgggtgaaaaaccgtacgcgtgcacgatctgtggcaaaaactttagccaatcgaacaacctgaaaacgcacatccggacgcacacgggcgaaaagccatacgcgtgtacgatctgcggcaagcggttcaatcagaagaacaacctgacgacgcacatgcgcacgcaccagctggtgtgtatggtgtgtggcgttcagttcgcgcacccgaccgatctggccaaccacatgaagtttcataacgacgaaaagccctacatttgctcggtgtgcaacaaagtgtacctcaatctggacgagctgacggagcacatgaagaaaacgcacaaccagatcaaaccgtaccggtgtcacatctgcgacaaaacgttcacccagtccaacaacctgaagacgcacatcaaaacgcacatcttccaggatccgtacaagtgccagatgtgttcccggtcgttccagaaggaggacgactactcgcagcacatgctcgtgcacacggccgacaaaccgtacgagtgtacgtactgtggcaagcggttcattcagtcgaacaacctgaaaacccacgtccggacgcacaccggggaaaagccgtacacctgtacgatctgcgcgaaaacgttcaaccagaagaacaacctcaacacgcacatgcgcatccacacgggcgagaagccgttcgagtgtacgatctgcgacaagcggttcaatcagtccaacaaccttaacaagcacatcaaaacgcacggccaggagaaggaccagcagcagcagcagcatccgcagcacgtgagttga
Protein Sequence: MLGKYGDASSSSMINLENGLRNRVLYHQNMMGMNLMAEFYHNPTGTVSASVGVATSHSQKMLNSLTGNILVPGVPSNHQQQLQHSNGTSLVTLPLGAAATAGVASSQQPLTLFQCQVCQKTFLSSTMLVVHMKTHDADYAARDETTGGYMPPSAMPPSSGNGTGSKTSPPSLLTQPNIKSEYVGGSRSGSVPLPDGGHSISGHHGGGGIVKQFDCHICHKSFMTLMNLNLHMKIHENEQKMTAHTYSQTIGGAGSGANSIIVGSSALSYQHHHSHHGQQQQQHHVMVATTVGGATTAVASLPPEGLCQICHKTFNSTEQFTAHMKMHEDEFKNRALYHSSVTAAAPGGNANGVVQPPNNPFTGGTATHGPFTPHVASSPVQQEPAKGHRCPICHKMSSNIIEHIKQHEGQLSMGGTNGASASPEGSPTTRGTDNATPGYQMNEESQSSQGDDSENGGTDGAGTDPRKQHECLICRKKFSSSGNLAIHIRVHSGEKPFKCSVCGKGFIQSNNLATHMKTHTGEKPYACTICGKNFSQSNNLKTHIRTHTGEKPYACTICGKRFNQKNNLTTHMRTHQLVCMVCGVQFAHPTDLANHMKFHNDEKPYICSVCNKVYLNLDELTEHMKKTHNQIKPYRCHICDKTFTQSNNLKTHIKTHIFQDPYKCQMCSRSFQKEDDYSQHMLVHTADKPYECTYCGKRFIQSNNLKTHVRTHTGEKPYTCTICAKTFNQKNNLNTHMRIHTGEKPFECTICDKRFNQSNNLNKHIKTHGQEKDQQQQQHPQHVS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00097213;
90% Identity: iTF_00097213;
80% Identity: iTF_00097213;