Acru005404.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles cruzii
Gene Symbol
-
Assembly
GCA_943734635.1
Location
OX030879.1:48059750-48062104[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 5.8e-05 0.0035 17.5 1.2 1 23 113 135 113 135 0.99
2 15 1.2e-05 0.00074 19.6 4.2 1 23 213 235 213 235 0.97
3 15 2.5e-05 0.0015 18.7 3.1 3 23 307 327 306 327 0.99
4 15 0.42 25 5.4 1.4 1 16 388 400 388 407 0.72
5 15 1.9e-06 0.00012 22.2 0.7 1 23 469 491 469 491 0.97
6 15 5.4e-08 3.3e-06 27.1 0.6 1 23 497 519 497 519 0.99
7 15 9.9e-09 6e-07 29.4 1.0 1 23 525 547 525 547 0.98
8 15 6.8e-09 4.2e-07 29.9 1.8 1 23 553 575 553 575 0.98
9 15 0.00028 0.017 15.4 0.2 2 23 578 599 577 599 0.95
10 15 0.00027 0.016 15.4 0.4 1 23 605 628 605 628 0.97
11 15 2.2e-08 1.3e-06 28.3 4.7 1 23 634 656 634 656 0.99
12 15 0.00019 0.012 15.9 1.4 1 23 662 684 662 684 0.99
13 15 3.1e-08 1.9e-06 27.8 1.8 1 23 690 712 690 712 0.99
14 15 1.1e-07 6.5e-06 26.1 1.6 1 23 718 740 718 740 0.99
15 15 2.8e-08 1.7e-06 28.0 2.0 1 23 746 768 746 768 0.98

Sequence Information

Coding Sequence
ATGCTGGGAAAGTATGGCGACGCGAGTTCCAGCTCGATGATTAACCTGGAAAATGGGCTCCGGAACCGTGTGCTGTACCACCAGAACATGATGGGCATGAATCTGATGGCCGAGTTCTACCACAACCCAACCGGCACCGTTTCCGCATCCGTCGGCGTTGCTACGTCCCACTCACAGAAGATGCTCAACAGTCTGACCGGAAACATACTGGTGCCTGGGGTGCCAAGCAACCACCAACAGCAGCTTCAGCATAGCAACGGTACATCACTAGTAACACTTCCCTTGGGAGCAGCCGCCACCGCCGGAGTAGCTTCATCGCAGCAACCGTTGACGCTGTTTCAGTGTCAAGTCTGTCAGAAAACTTTCCTCTCCAGCACGATGCTGGTCGTGCACATGAAAACTCACGATGCCGATTATGCGGCGCGCGATGAGACCACCGGCGGCTACATGCCACCTTCCGCGATGCCACCTTCGTCTGGAAACGGAACAGGCAGCAAAACTAGTCCCCCGTCGCTACTCACACAGCCCAACATCAAGAGCGAGTACGTGGGGGGCTCCCGGTCCGGTTCGGTACCGCTCCCTGACGGTGGTCACAGCATCTCTGGCCACCACGGTGGTGGTGGTATCGTCAAGCAGTTTGACTGCCACATCTGCCACAAATCTTTCATGACACTGATGAACCTCAATCTCCACATGAAAATTCACGAAAACGAACAAAAAATGACCGCTCACACGTACTCGCAGACGATCGGTGGTGCCGGAAGTGGAGCCAACAGCATAATCGTGGGCTCCAGTGCGCTCAGCTACCAGCATCATCACAGCCACCACGGCCAGCAGCAGCAGCAGCACCACGTGATGGTGGCCACTACTGTCGGAGGCGCCACTACTGCGGTGGCTTCCTTGCCCCCCGAGGGCCTATGTCAAATTTGCCATAAAACGTTCAACAGTACCGAACAATTTACGGCACACATGAAGATGCACGAGGATGAGTTCAAAAATCGGGCTCTTTATCACTCCTCGGTGACGGCGGCGGCACCCGGTGGCAACGCTAACGGGGTTGTACAGCCACCAAACAATCCGTTCACCGGTGGCACCGCGACACACGGACCGTTTACGCCCCACGTGGCGTCGTCGCCGGTGCAACAAGAACCGGCGaaggggcaccgttgtccgatctgtcacaaaatgtccagcaacattatcgagcacatcaagcagcacgaaggtcagctgtcgatgggcggcaccaacggtgcgtccgcttcgcccgaagggagccccaccaccagggggacggataatgccacacccgggtaccagatgaacgaggaatcgcaatcgtcgcagggagatgatagcgagaatggtggcaccgatggcgcgggaaccgatccacggaagcagcacgagtgtttgatttgtcgcaaaaagttctccagctccggcaatctggccatccacatacgcgttcactcgggtgagaaaccgttcaaatgtagcgtgtgcgggaagggttttattcagtcgaataatttggccacgcacatgaaaacgcatacgggtgaaaaaccgtacgcgtgcacgatctgtggcaaaaactttagccaatcgaacaacctgaaaacgcacatccggacgcacacgggcgaaaagccatacgcgtgtacgatctgcggcaagcggttcaatcagaagaacaacctgacgacgcacatgcgcacgcaccagctggtgtgtatggtgtgtggcgttcagttcgcgcacccgaccgatctggccaaccacatgaagtttcataacgacgaaaagccctacatttgctcggtgtgcaacaaagtgtacctcaatctggacgagctgacggagcacatgaagaaaacgcacaaccagatcaaaccgtaccggtgtcacatctgcgacaaaacgttcacccagtccaacaacctgaagacgcacatcaaaacgcacatcttccaggatccgtacaagtgccagatgtgttcccggtcgttccagaaggaggacgactactcgcagcacatgctcgtgcacacggccgacaaaccgtacgagtgtacgtactgtggcaagcggttcattcagtcgaacaacctgaaaacccacgtccggacgcacaccggggaaaagccgtacacctgtacgatctgcgcgaaaacgttcaaccagaagaacaacctcaacacgcacatgcgcatccacacgggcgagaagccgttcgagtgtacgatctgcgacaagcggttcaatcagtccaacaaccttaacaagcacatcaaaacgcacggccaggagaaggaccagcagcagcagcagcatccgcagcacgtgagttga
Protein Sequence
MLGKYGDASSSSMINLENGLRNRVLYHQNMMGMNLMAEFYHNPTGTVSASVGVATSHSQKMLNSLTGNILVPGVPSNHQQQLQHSNGTSLVTLPLGAAATAGVASSQQPLTLFQCQVCQKTFLSSTMLVVHMKTHDADYAARDETTGGYMPPSAMPPSSGNGTGSKTSPPSLLTQPNIKSEYVGGSRSGSVPLPDGGHSISGHHGGGGIVKQFDCHICHKSFMTLMNLNLHMKIHENEQKMTAHTYSQTIGGAGSGANSIIVGSSALSYQHHHSHHGQQQQQHHVMVATTVGGATTAVASLPPEGLCQICHKTFNSTEQFTAHMKMHEDEFKNRALYHSSVTAAAPGGNANGVVQPPNNPFTGGTATHGPFTPHVASSPVQQEPAKGHRCPICHKMSSNIIEHIKQHEGQLSMGGTNGASASPEGSPTTRGTDNATPGYQMNEESQSSQGDDSENGGTDGAGTDPRKQHECLICRKKFSSSGNLAIHIRVHSGEKPFKCSVCGKGFIQSNNLATHMKTHTGEKPYACTICGKNFSQSNNLKTHIRTHTGEKPYACTICGKRFNQKNNLTTHMRTHQLVCMVCGVQFAHPTDLANHMKFHNDEKPYICSVCNKVYLNLDELTEHMKKTHNQIKPYRCHICDKTFTQSNNLKTHIKTHIFQDPYKCQMCSRSFQKEDDYSQHMLVHTADKPYECTYCGKRFIQSNNLKTHVRTHTGEKPYTCTICAKTFNQKNNLNTHMRIHTGEKPFECTICDKRFNQSNNLNKHIKTHGQEKDQQQQQHPQHVS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00097450; iTF_00094844; iTF_00094613;
90% Identity
iTF_00097450; iTF_00094844; iTF_00094613;
80% Identity
iTF_00097450;