Abel004369.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles bellator
Gene Symbol
-
Assembly
GCA_943735745.2
Location
OX030927.2:45716718-45719072[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 5.7e-05 0.0033 17.5 1.2 1 23 111 133 111 133 0.99
2 15 1.2e-05 0.00069 19.6 4.2 1 23 210 232 210 232 0.97
3 15 3.3e-05 0.0019 18.2 2.4 3 23 306 326 305 326 0.99
4 15 0.41 23 5.4 1.4 1 16 387 399 387 406 0.72
5 15 1.9e-06 0.00011 22.2 0.7 1 23 469 491 469 491 0.97
6 15 5.2e-08 3e-06 27.1 0.6 1 23 497 519 497 519 0.99
7 15 9.7e-09 5.6e-07 29.4 1.0 1 23 525 547 525 547 0.98
8 15 6.7e-09 3.8e-07 29.9 1.8 1 23 553 575 553 575 0.98
9 15 0.00027 0.016 15.4 0.2 2 23 578 599 577 599 0.95
10 15 0.00026 0.015 15.4 0.4 1 23 605 628 605 628 0.97
11 15 2.2e-08 1.2e-06 28.3 4.7 1 23 634 656 634 656 0.99
12 15 0.00026 0.015 15.4 1.5 1 23 662 684 662 684 0.98
13 15 3e-08 1.7e-06 27.8 1.8 1 23 690 712 690 712 0.99
14 15 1e-07 6e-06 26.1 1.6 1 23 718 740 718 740 0.99
15 15 2.7e-08 1.6e-06 28.0 2.0 1 23 746 768 746 768 0.98

Sequence Information

Coding Sequence
ATGCTGGGAAAATATGGCGATGCGAGTTCCAGCTCGATGATTAACCTGGAAAATGGGCTCCGGAACCGTGTGCTCTACCATCAAAACATGATGGGCATGAATCTGATGGCCGAGTTCTACCACAATCCAACAGCCACTGTGTCCGCATCCGTCGGCGTTGGCACGACCCATTCACAGAAGATGCTCAACAGTCTGACCGGAAACATTCTAGTGCCTGGGGCAAGCAATCACCAACAGCAAGCGCAGCATAGCAACGGTACATCACTAGTAACACTTCCCTTGGGGGCAGCCAACGCCGGAGCAGCCTCATCGCAGCAACCGTTGACTCTGTTTCAGTGTCAAGTCTGTCAGAAAACTTTCCTCTCCAGCACGATGCTGGTCGTGCACATGAAGACTCACGATGCCGATTATACGACGCGCGATGAGACCGCTGGCGGCTACATGCCACCTTCCGCTGGAAGCGGAACGAGCAGTAAAACTAGTCCCCCGTCGCTACTCACACAGCCCATCATCAAGAGCGAGTACGCCGGCGGAGCGCTGCCAGTGGGAGgttcccggtccggttcggtcccgCTTCCTGACGGTGGTCAAAACATCTCTTCACACCACGGTGGTATCGTCAAGCAGTTTGACTGTCACATCTGCCACAAATCTTTCATGACACTGATGAACCTCAATCTACATATGAAAATTCacgaaaatgaacaaaaaatgacCGCGCAAACGTATTCGCACACGATCGGTGGTGCCGGAAGTGGTACCAGCAGCATAATCGTGGGGTCCAGTGCTCTCAGCTACCAGCATCACAGCcaccacggccagcagcagcagcaacagcaccacgtGATGTTGGCCACTACCGTCGGAACCGCTTCCACCACTCCATCCTTACCTCCCTCTGTGACCGAAGGCCTGTGCCAGATTTGCCATAAGACGTTCAACAATACCGAACAATTTGTAGCGCACATGAAGATGCATGAAGATGAGTTCAAAAATCGGGCTCTTTATCACtcctcggcgacggcggcacccGGAAACCCGAACGGGTTGGCACAGCCACCGAACAATCCGTTCGGCGGAACACTCTCAGCTACCGCAACACACGGACAGTTTACGCCTCATGTCGCGTCGCCAGTGCAACAAGAAACCACGAAGGGGCACCGTTGTCCGATCTGTCACAAAATGTCCAGCAACATTATCGAGCATATAAAGCAGCACGAAGGTCAGCTGTCGATGGGAGGTACGAACGGAACATCTGCCTCGCCCGAAGGGAGCCCCACCAGGGGGACGGATAATGCCACACCCGGGTATCAGTTGAACGAGGAATCGCAATCGTCGCAGGGAGATGACAGCGAGAACGGTACGATTGGCGGCGATGCCGCGGGAACCGATCCACGGAAGCAGCACGAGTGTTTGATTTGTCGCAAAAAGTTCTCCAGCTCCGGCAACCTGGCCATCCACATACGCGTCCACTCGGGTGAGAAACCGTTCAAATGTAGCGTGTGCGGGAAGGGTTTCATCCAGTCCAACAATCTGGCCACGCACATGAAAACGCACACAGGCGAAAAACCGTACGCCTGCACGATCTGCGGCAAAAACTTTAGCCAATCGAACAACCTGAAAACGCACATCCGGACGCACACGGGCGAAAAGCCGTACGCGTGTACAATCTGCGGCAAGCGGTTCAATCAGAAGAACAACCTGACGACGCATATGCGCACGCACCAGCTGGTGTGTATGGTGTGCGGCGTTCAGTTCGCGCACCCGACCGATCTGGCCAACCACATGAAGTTTCACAACGACGAAAAGCCCTACATCTGCTCGGTGTGCAACAAGGTGTACCTCAATCTGGACGAGCTGACGGAGCACATGAAGAAAACGCACAACCAGATCAAACCGTATCGGTGTCACATCTGCGACAAAACGTTCACCCAGTCCAATAACCTGAAGACGCACATCAAAACGCACATCTTCCAAGATCCGTTCAAGTGTCAGATGTGTTCCCGGTCGTTCCAGAAGGAGGACGACTACTCGCAGCACATGCTCGTGCACACGGCCGACAAACCGTATGAGTGTACGTACTGTGGCAAGCGGTTCATTCAGTCCAACAACCTGAAAACGCACGTCCGGACACACACGGGCGAAAAGCCGTACACCTGTACGATCTGCGCGAAAACGTTCAATCAGAAGAATAACCTCAACACGCATATGCGCATCCACACGGGCGAGAAACCGTTCGAGTGTACGATCTGCGACAAGCGGTTCAATCAGTCCAACAACCTTAACAAGCACATCAAAACACACGGCCAGGAGaaggatcagcagcagcagcagcatcagcagcacgtGAGTTGA
Protein Sequence
MLGKYGDASSSSMINLENGLRNRVLYHQNMMGMNLMAEFYHNPTATVSASVGVGTTHSQKMLNSLTGNILVPGASNHQQQAQHSNGTSLVTLPLGAANAGAASSQQPLTLFQCQVCQKTFLSSTMLVVHMKTHDADYTTRDETAGGYMPPSAGSGTSSKTSPPSLLTQPIIKSEYAGGALPVGGSRSGSVPLPDGGQNISSHHGGIVKQFDCHICHKSFMTLMNLNLHMKIHENEQKMTAQTYSHTIGGAGSGTSSIIVGSSALSYQHHSHHGQQQQQQHHVMLATTVGTASTTPSLPPSVTEGLCQICHKTFNNTEQFVAHMKMHEDEFKNRALYHSSATAAPGNPNGLAQPPNNPFGGTLSATATHGQFTPHVASPVQQETTKGHRCPICHKMSSNIIEHIKQHEGQLSMGGTNGTSASPEGSPTRGTDNATPGYQLNEESQSSQGDDSENGTIGGDAAGTDPRKQHECLICRKKFSSSGNLAIHIRVHSGEKPFKCSVCGKGFIQSNNLATHMKTHTGEKPYACTICGKNFSQSNNLKTHIRTHTGEKPYACTICGKRFNQKNNLTTHMRTHQLVCMVCGVQFAHPTDLANHMKFHNDEKPYICSVCNKVYLNLDELTEHMKKTHNQIKPYRCHICDKTFTQSNNLKTHIKTHIFQDPFKCQMCSRSFQKEDDYSQHMLVHTADKPYECTYCGKRFIQSNNLKTHVRTHTGEKPYTCTICAKTFNQKNNLNTHMRIHTGEKPFECTICDKRFNQSNNLNKHIKTHGQEKDQQQQQHQQHVS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00097213;
90% Identity
iTF_00097213;
80% Identity
iTF_00094844;