Acou008770.1
Basic Information
- Insect
- Anopheles coustani
- Gene Symbol
- -
- Assembly
- GCA_943734705.2
- Location
- OX030901.1:9575535-9576050[-]
Transcription Factor Domain
- TF Family
- HMGA
- Domain
- HMGA domain
- PFAM
- AnimalTFDB
- TF Group
- Unclassified Structure
- Description
- This entry represents the HMGA family, whose members contain DNA-binding domains, also known as AT hooks due to their ability to interact with the narrow minor groove of AT-rich DNA sequences. They play an important role in chromatin organisation [1]. The high mobility group (HMG) proteins are the most abundant and ubiquitous nonhistone chromosomal proteins. They bind to DNA and to nucleosomes and are involved in the regulation of DNA-dependent processes such as transcription, replication, recombination, and DNA repair. They can be grouped into three families: HMGB (HMG 1/2), HMGN (HMG 14/17) and HMGA (HMG I/Y). The characteristic domains are: AT-hook for the HMGA family, the HMG Box for the HMGB family, and the nucleosome-binding domain (NBD) for the members of the HMGN family [2].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.00093 18 5.2 1.2 4 15 5 16 3 17 0.83 2 4 0.44 8.5e+03 -3.4 0.4 15 19 35 39 34 39 0.60 3 4 1.1e-10 2.1e-06 27.3 7.5 4 21 56 73 54 74 0.93 4 4 0.16 3.1e+03 -2.0 2.8 12 18 88 94 81 96 0.68
Sequence Information
- Coding Sequence
- ATGTCCGACACGGAGGTCGTTGAACCGAAGAAGGGCCGTGGACGCCCGCCAAACGCGGAAAAGAACAGCGTTGCACCGAAAAAACGTGCTCGCGCCCTTTCACCGAAGGAATCAAAGTTGGAGGAACGCGGTGAGAAGGACAAGGTGGTCGCATCGGACGATGGCGAGGAACCATCGCCAAAGCGGGGACGTGGACGCCCGAAGGGAAGCACCAAGAAGGTAGCGAAGCCGACCAAGAAAGCTCCCTCAGCACCGGTTGGCCGAGGCCGGGGGCGCGGCAAGAAAAAGCCAATGAAAGAGGAATCCTCCGAagaggaggacgacgacgatgacgaggacgaggaggacgacgagCCGGAGGATAGCGAGGGAAACGAGGAAAACTACGGAAACGATGAGTCCGACTCGTAA
- Protein Sequence
- MSDTEVVEPKKGRGRPPNAEKNSVAPKKRARALSPKESKLEERGEKDKVVASDDGEEPSPKRGRGRPKGSTKKVAKPTKKAPSAPVGRGRGRGKKKPMKEESSEEEDDDDDEDEEDDEPEDSEGNEENYGNDESDS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00107683;
- 90% Identity
- iTF_00107683;
- 80% Identity
- iTF_00107683;