Basic Information

Insect: Anopheles coluzzii
Gene Symbol: grau
Assembly: GCA_016097175.1
Location: CM027927.1:53519839-53522041[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 9.3 4.9e+02 1.2 0.3 1 8 32 39 32 47 0.87

2 13 2.3 1.2e+02 3.1 0.1 3 23 201 224 199 224 0.79

3 13 1.9e-05 0.001 19.1 0.4 2 23 232 253 231 253 0.96

4 13 3.7 2e+02 2.5 0.6 12 23 309 321 307 321 0.83

5 13 0.0029 0.15 12.2 0.6 2 23 329 350 328 350 0.98

6 13 0.081 4.3 7.7 0.1 9 23 438 453 436 453 0.90

7 13 0.0063 0.33 11.2 0.9 2 23 461 482 460 482 0.96

8 13 1.5e-05 0.00078 19.5 0.3 1 23 513 536 513 536 0.96

9 13 0.0042 0.22 11.8 0.5 3 23 543 563 541 563 0.95

10 13 7.4e-07 3.9e-05 23.6 0.4 1 23 569 591 569 591 0.96

11 13 0.00045 0.023 14.8 0.3 2 23 624 646 623 646 0.96

12 13 3e-05 0.0016 18.5 2.2 2 20 653 671 653 673 0.94

13 13 6.3e-05 0.0033 17.5 2.7 3 23 682 702 680 702 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	9.3	4.9e+02	1.2	0.3	1	8	32	39	32	47	0.87
2	13	2.3	1.2e+02	3.1	0.1	3	23	201	224	199	224	0.79
3	13	1.9e-05	0.001	19.1	0.4	2	23	232	253	231	253	0.96
4	13	3.7	2e+02	2.5	0.6	12	23	309	321	307	321	0.83
5	13	0.0029	0.15	12.2	0.6	2	23	329	350	328	350	0.98
6	13	0.081	4.3	7.7	0.1	9	23	438	453	436	453	0.90
7	13	0.0063	0.33	11.2	0.9	2	23	461	482	460	482	0.96
8	13	1.5e-05	0.00078	19.5	0.3	1	23	513	536	513	536	0.96
9	13	0.0042	0.22	11.8	0.5	3	23	543	563	541	563	0.95
10	13	7.4e-07	3.9e-05	23.6	0.4	1	23	569	591	569	591	0.96
11	13	0.00045	0.023	14.8	0.3	2	23	624	646	623	646	0.96
12	13	3e-05	0.0016	18.5	2.2	2	20	653	671	653	673	0.94
13	13	6.3e-05	0.0033	17.5	2.7	3	23	682	702	680	702	0.97

Sequence Information

Coding Sequence: ATGTTCATGCCGCGGGAGGACGACCCGAAGGAGATGCCGTATCTGGTGTGGAAGCACGTCGGGCTACAGTTTCCGCAGGAGGCAGGCAAACACTACGTCTGCCGGGACTGCGGGTTCGCGGTGTACGAGTTTAACCGATTCTACTTGATGGTGCAGAACGTACACCAGGAACGGCAGGCCGCAGCAGCGGCAGCAGTACTGCAACCGAAGCAAGAGCCGCCTATGCAGGAGCAGGTACAATACAATGCTGAGCAGGCGGCGGCGGCGTTGGAAGGCGTCAATCAGAACGGTCATCATGGAGGCGAGCAAAAGTTTGACCCGTCGCCGCTGGTGGACGGGCCCGTGCCGTTGCTGTCCGATGTTCCGGATTATGGGATGAAGCACGAAGTGAACGGAATGCTACCATCCGGCGGATCCGGGGTAACGGCTGTCGGGGGCAACGGTACAGCGGCAGAGTGTCCGTCGGTGTACACGTCGCAGCACAACGATACGGAACCGGAAAGCAGCCGAATCCGGCCGGTCACGGGCAACACACCGAGCAGCCGGAAGCGCCGCAACCAAGAGATGGACGATGAGATTATCGACTTTTACAAGCTGGTCTGTGACGTGTGCGAGGAACGCATCGAGTACGGCACGATGAAGGAGCTGAACCAGCACATGAAGCTGATGCACGGGGAGGAGACGGGCCGGGTCAGCTGTCCGCAGTGTGGCAAGATGTTCCGCACGCGGGGGAAGCTGCTGGAGCACAAGAGCGTGCACCAGCGACAGGACGCCACGTCCGAGGACGACGCGGAGAAGCTGCAGTCCGAGCAGATGGACAAGGAGATACTGGAGTTTTACAAGCGCATCAGCTGCGATGTGTGCGACACGGCGGCCAGTGCTGCTGCCGGGGCCGGTCCACAGGCCAGCGCGATGCTGTACGCGACGGTGAAGGAGCTAAACCACCACATGCGGCTGGTGCACGGGCAGCAGGCCGGTACGGTAAAGTGTCCACTGTGTGAGAAGAAGATCCGTACGCGCCCGAAGCTGCTCGAGCACAAGCGCATGCACCAGCCAAACGCGCTGCTGGAGGAAGATTCCGGCAAGTCGGGCAACCCGGGCGGCGAGCCGGGGCCCGAGCTGACCGAGGAGCAGAAGCAGACGCTAGATAGAGAAATATTCGATTTCTACAAACCCATCATATGTGAGATTTGCGATCCGGAAAAGGTCGCTGTGGCTGTCGCGGTGGCCGGCCCCGGCGGTGACCCGGGCGGTGTTGCCGCGGGAGCGGGCCATCCGGAAGCGGCAGCAGCAGCAACGACCCAGGAGGAGGAGTACCGGTCGCTGAAGCAGCTGAACCAGCACATGCGGACGGTGCACGGGCTCGAGTCGGGCACGGTCAAGTGTCAGCTGTGCGCGAAAAAGTTTCGCTCGCGCGTCAAGCTGGTCGAGCATAAGGATATGCACGAGAATCCGGAGCGGTTCCGGTGCGGCGTGTGCCAGGAGGTGCACCAGAACCTGGAGGAGCACATGCAGAACAAGCACCAGGAGTGGGAGTTTGCTTGCGAGGAGTGCGGCAAGCGGTTTCCTTTCAAGAACAGACTCACTGCCCACATGGCCAAGGTGCACATGAAGAAGGACATTATCTGTGAGGAATGTAACAAACCATTTACAAAGTTCAGCATCGAGAAACACAAGAAAACGGTCCACGGTCACGGTGGGACGTTCATCTGTGAAAACTGCCCGAAAACGTTCAAGACGCGCGTCTCGCTCGAACGACACATGGAGGGGCATAACAACGGGGAGCAGCAGCAGCCGCCGCAGCAGCAGCAACCGCAACCGCTCCCACTGCCGCTACCGCAGCAACAACCGAGCTCTGCCGCGACCGTCAGCTGCTCCCTGTGCAACTCCGTCCTGAAGGACGAGTACAACCTGAAGGCCCACATGAAGCGCATCCACGCGGAGCAGACGCCGGCGACGTGCAACACGTGCGGCAAGACGTTCAAATCGAAGCACAGTCTCAACACGCACACCGCGAACGTGTGCACGACACGGCTCTTTGGCTGCACGACCTGCGGCAAGCAGTTTAAGAAGCGGACAAAGTTGAAACAACACATGACGATTCACCCACGCGGCGCCGACTAA
Protein Sequence: MFMPREDDPKEMPYLVWKHVGLQFPQEAGKHYVCRDCGFAVYEFNRFYLMVQNVHQERQAAAAAAVLQPKQEPPMQEQVQYNAEQAAAALEGVNQNGHHGGEQKFDPSPLVDGPVPLLSDVPDYGMKHEVNGMLPSGGSGVTAVGGNGTAAECPSVYTSQHNDTEPESSRIRPVTGNTPSSRKRRNQEMDDEIIDFYKLVCDVCEERIEYGTMKELNQHMKLMHGEETGRVSCPQCGKMFRTRGKLLEHKSVHQRQDATSEDDAEKLQSEQMDKEILEFYKRISCDVCDTAASAAAGAGPQASAMLYATVKELNHHMRLVHGQQAGTVKCPLCEKKIRTRPKLLEHKRMHQPNALLEEDSGKSGNPGGEPGPELTEEQKQTLDREIFDFYKPIICEICDPEKVAVAVAVAGPGGDPGGVAAGAGHPEAAAAATTQEEEYRSLKQLNQHMRTVHGLESGTVKCQLCAKKFRSRVKLVEHKDMHENPERFRCGVCQEVHQNLEEHMQNKHQEWEFACEECGKRFPFKNRLTAHMAKVHMKKDIICEECNKPFTKFSIEKHKKTVHGHGGTFICENCPKTFKTRVSLERHMEGHNNGEQQQPPQQQQPQPLPLPLPQQQPSSAATVSCSLCNSVLKDEYNLKAHMKRIHAEQTPATCNTCGKTFKSKHSLNTHTANVCTTRLFGCTTCGKQFKKRTKLKQHMTIHPRGAD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00101146;
90% Identity: iTF_00104589;
80% Identity: -