Acol013972.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles coluzzii
Gene Symbol
zfh1
Assembly
GCA_016097175.1
Location
CM027930.1:20407410-20410952[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 3.7e-06 0.0002 21.3 2.8 1 23 279 301 279 301 0.99
2 15 0.00047 0.024 14.7 4.9 1 23 313 335 313 335 0.96
3 15 1.5e-05 0.00081 19.4 0.8 2 23 345 366 344 366 0.95
4 15 3.8e-06 0.0002 21.3 3.8 1 23 372 394 372 394 0.99
5 15 0.02 1.1 9.6 0.1 2 23 402 423 401 423 0.97
6 15 9.8e-05 0.0051 16.9 3.4 1 23 429 452 429 452 0.94
7 15 0.004 0.21 11.8 5.4 1 21 458 478 458 479 0.94
8 15 0.37 19 5.6 4.7 3 23 487 508 485 508 0.91
9 15 6.8e-05 0.0036 17.4 0.5 1 23 554 576 554 576 0.97
10 15 0.00014 0.0074 16.4 0.2 1 23 587 609 587 609 0.97
11 15 0.00091 0.048 13.8 3.3 1 23 634 656 634 656 0.98
12 15 0.37 19 5.6 2.4 2 23 692 713 691 713 0.94
13 15 0.00079 0.041 14.0 5.0 1 23 719 741 719 741 0.98
14 15 4.5e-07 2.4e-05 24.2 1.5 1 23 749 771 749 771 0.99
15 15 0.00053 0.028 14.6 0.7 1 23 777 800 777 800 0.96

Sequence Information

Coding Sequence
ATGGAATACAACACCTACAACAAACCGTACTGTGGCATATCGCAGCCGACCATACCACCAGCAGCAGCAGCAGTCCCAGGCAGCTCCGGGTTCTTTCCGGCCAATGATACCGCACCGTCACCGTTCCTTAAAGTGCCCAACCCACCGTACATCAAGCAGGAGACGGTCCCGGTGGGCGGAGAATCGGTTATCCCGGGTGGAACGGTAACACCGCCCGTCAACTACAGCCAGGATCATCATCATTATGGAACGGCGGGGAGTTACGGCGAACCGGGCGATGTGGAGAAGCCACCCCTGTTCTATCGCAAAGCGTTTGACATGCCGTACATGGCGACACCGTACGTGCAGTCCCATCTTGCGCAGCAATTTCCCCAACATCTTCCCTCACATCCTAACCAACTGCCGCCTCACCAGCACCATGCAGTACACAGTCAGCCGGTTCCTCATTTCCAACACCAGCAGCAGCAGCAGCTCCTCCACCACCACCACCAGCAGCCACTTGCGCCACTACCTACGATCGTGCCATCCGATATGCATTCACCACAGCAACTTGGACCGGAGCAGTTACAGCGAGCCCAGCCACAGCAACAGCACCAACAGCAACAGCATCCGTCGAGCTTCCACGACTACTTTGACCACCTGGATCCTTCCTCCCTGGAACCGTATGCGTACGTGCTTCAAAAGCCCGCTCCGCCGGCTCCACCAATCCAGCCCAGTGAAACTGGTTCCCCGCTGCCTGCCTCATACCCGACCGCCTCGCCAGTTGCTCCACCAGCAGCAACACCTTCCCCGTACACCCCGCTGTGTGAGCCGCCGGACAGCAGCAAGGTACGCTTCAAGTGTGAAACCTGTCCGAAATCGTTCGACACGAAGCAGAAGCTGGAAAAGCACAACCGCACCCATCAGCCGAACGGCGGGGGTGCGGCCGGGCTCGAGTTTAAATGCCGCATGTGCGACAAAACGTTCCGCACGAAGAGTACGCTCATCTGCCACGAGAAGGTGCACGGCGAGAGTGGCCTAGGCAGCAGCTGCTCCTGCGTCGAGTGCGGCAAGGTGTTTGCGACGGAGGAAAAGCTACAGGTGCACCGGCGGCTGCACACGGGCGAAAAACCGTACCAGTGCAAGGTGTGCCTGAAGTGCTTCAACCACCAATCGAACCTGATCGTGCACGCGCGCATCCACGACAAGGTGAAGCAGGCGCTCAAGTGTGCCCGGTGCAGCAAGGTGCTGGACAGCGAGGAGCGGCTCGCCGTCCATATGCGGCTGCACACGGGCGAAAAGCCGTACAAGTGTTCGTACTGCGACAAGCGCTTCAATCACAAGAGCACGGTCAGCACGCACGAGAAGGCGGCCCACATTGCGGCCAACTCGTACCGGTGTGGCCGCTGCCACAAGACGTTCAACCAGAAGTGCCAGCTGCAGTACCACGAGAAGCTGCAGGAGGAGCACACGATCGCGTGCGAGCACTGCGAGAAGGTGTTCTGCTACAAGGCGAGCCACAAGGAGCACCTGTTTAAGGTGCACTTCCCGCGGCCGAAAAAGAAAGCGCAGCGGAAGGGAGGAAGTCTGCGGGAAGGAGATGAACAGCAGCAGCAGGAATCGGGCACTGGCGGTGCAATGGCTGGAAGCAACGATGGGGGTAATCAGGGCCGCAACAAGTTCAAATGTACCGTGTGCGATCGTCGGTTTTACTACGAGCGGGCGCTCGAGATGCATATGGGCGTGCACGATGCATCGCTGGACGTGAACGTGCTGTACTTTTCCTGCGACTACTGTCCGGAAACGTTCACCGAGGAGGAGACGCTGCAGCAGCACGAGGCCCGCCACGTGGCCGACGGGACGACCGATTTCCGCGCAAACATGAAACGGGCCGAGGAAGGGGGAAACGCCACCACCGGGCACAGGTGTCCGCTGTGCTTTAAGCAGTTTGAGGATGAACCATCCTTACGCGAACATCACCGTTCGCACCTGTGCCCATTTCCCGACTGTGCGCGGTGCGACCCAGTACGGCGCGATGATGCGTTCGACCTGACGCGCAGTACGTACGATCCGGCGGACGATACGCAACCGACGGTGTGTAACGTGTGCCATCGCGTACTGCCAACGTTCGAGGCGTACCAGAACCACTTCCACTACCATACGTCGCGCGTCCCGTTCTACTGCTACCACTGCCGGGAGGAGTTTAACGACAAGCGGGAGCTGTACAACCACACGCGAACGCATGCGCCGCGCGCACCCGAATCGTACACGTGCGAGGTGTGCGCGAAGGTGTTCTCGACCAAGGGGAACTTTAAGCGGCATCTGAAATCTCACGAAGCGGTCCGGGCGTTCGCGTGCGATCGCTGCTCGAAGCAGTACGACTACAAGAGTGCGCTCGAGGTGCATCTGAAGCGTTCGCACGGTATTGAGCTGTGA
Protein Sequence
MEYNTYNKPYCGISQPTIPPAAAAVPGSSGFFPANDTAPSPFLKVPNPPYIKQETVPVGGESVIPGGTVTPPVNYSQDHHHYGTAGSYGEPGDVEKPPLFYRKAFDMPYMATPYVQSHLAQQFPQHLPSHPNQLPPHQHHAVHSQPVPHFQHQQQQQLLHHHHQQPLAPLPTIVPSDMHSPQQLGPEQLQRAQPQQQHQQQQHPSSFHDYFDHLDPSSLEPYAYVLQKPAPPAPPIQPSETGSPLPASYPTASPVAPPAATPSPYTPLCEPPDSSKVRFKCETCPKSFDTKQKLEKHNRTHQPNGGGAAGLEFKCRMCDKTFRTKSTLICHEKVHGESGLGSSCSCVECGKVFATEEKLQVHRRLHTGEKPYQCKVCLKCFNHQSNLIVHARIHDKVKQALKCARCSKVLDSEERLAVHMRLHTGEKPYKCSYCDKRFNHKSTVSTHEKAAHIAANSYRCGRCHKTFNQKCQLQYHEKLQEEHTIACEHCEKVFCYKASHKEHLFKVHFPRPKKKAQRKGGSLREGDEQQQQESGTGGAMAGSNDGGNQGRNKFKCTVCDRRFYYERALEMHMGVHDASLDVNVLYFSCDYCPETFTEEETLQQHEARHVADGTTDFRANMKRAEEGGNATTGHRCPLCFKQFEDEPSLREHHRSHLCPFPDCARCDPVRRDDAFDLTRSTYDPADDTQPTVCNVCHRVLPTFEAYQNHFHYHTSRVPFYCYHCREEFNDKRELYNHTRTHAPRAPESYTCEVCAKVFSTKGNFKRHLKSHEAVRAFACDRCSKQYDYKSALEVHLKRSHGIEL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00101103;
90% Identity
iTF_00093613;
80% Identity
-