Aara009082.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles arabiensis
Gene Symbol
-
Assembly
GCA_016920715.1
Location
NC:20176615-20179621[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 3.5e-06 0.00017 21.3 2.8 1 23 279 301 279 301 0.99
2 15 0.00044 0.021 14.7 4.9 1 23 312 334 312 334 0.96
3 15 1.4e-05 0.00069 19.4 0.8 2 23 344 365 343 365 0.95
4 15 3.5e-06 0.00017 21.3 3.8 1 23 371 393 371 393 0.99
5 15 0.019 0.91 9.6 0.1 2 23 401 422 400 422 0.97
6 15 9.2e-05 0.0044 16.9 3.4 1 23 428 451 428 451 0.94
7 15 0.0038 0.18 11.8 5.4 1 21 457 477 457 478 0.94
8 15 0.34 16 5.6 4.7 3 23 486 507 484 507 0.91
9 15 6.4e-05 0.0031 17.4 0.5 1 23 553 575 553 575 0.97
10 15 0.00013 0.0063 16.4 0.2 1 23 586 608 586 608 0.97
11 15 0.00086 0.041 13.8 3.3 1 23 633 655 633 655 0.98
12 15 0.34 16 5.6 2.4 2 23 691 712 690 712 0.94
13 15 0.00074 0.035 14.0 5.0 1 23 718 740 718 740 0.98
14 15 4.2e-07 2e-05 24.2 1.5 1 23 748 770 748 770 0.99
15 15 0.00049 0.024 14.6 0.7 1 23 776 799 776 799 0.96

Sequence Information

Coding Sequence
ATGGAATACAACAACACCTACAACAAACCGTACTGTGGCATATCGCAGCCGACcataccaccagcagcagcagccgtccCAGGCAGCTCCGGGTTCTTCCCGGCCAATGACACCGCACCGTCACCGTTCCTTAAAGTGCCCAATCCACCGTACATCAAGCAGGAGACGGTCCCGGTGGGCGGAGAATCGGTTATTCCGGGTGGAACGGTAACACCGCCCGTCAACTACAGCCaggatcatcatcattatggCACGGCGGGGAGTTACGGCGAACCGGGCGATGTGGAGAAACCTCCCCTGTTCTATCGCAAAGCGTTTGACATGCCGTACATGGCGACACCGTACGTGCAGTCCCATCTTGCGCAACAGTTTCCTCAACATCTTCCCTCACATCCTAACCAACTGCCGCCTCACCAGCACCATGCAGTACACAGTCAGCCGGTTCCTCATTTccaacaccaacagcagcagcagctcctccaccaccaccagcagccacTTGCGCCACTACCTACGATCGTGCCATCCGATATGCATTCACCACAGCAACTTGGACCGGAGCAGTTACAGCGAGCCcagccacagcaacagcaccaacagcaacagcatccgTCGAGCTTCCACGACTACTTTGACCACCTGGATCCTTCCTCCCTGGAACCGTATGCGTACGTGCTTCAAAAGCCTGCCCCGCCGGTTCCACCGATCCAGCCCAGTGAAACTGGTTCCCCGCTGCCTGCCTCATACCCGACCGCCTCGCCAGTtgctccaccagcagcaacaccttCCCCGTACACCCCGCTGTGTGAGCCGCCGGACAGCAGCAAGGTACGCTTCAAGTGTGAAACCTGTCCGAAATCGTTCGACACGAAGCAGAAGCTGGAAAAGCACAACCGCACCCACCAGCCGAACGGTGGTGCGGCCGGGCTCGAGTTTAAATGCCGCATGTGCGACAAAACGTTCCGCACGAAGAGTACGCTCATCTGCCACGAGAAGGTGCACGGCGAGAGTGGCCtaggcagcagctgctcctGCGTCGAGTGCGGCAAGGTGTTTGCGACGGAGGAAAAGCTACAGGTGCACCGGCGGCTGCACACGGGCGAAAAACCGTACCAGTGCAAGGTGTGCCTGAAGTGCTTCAACCACCAATCGAACCTGATCGTGCACGCGCGCATCCACGACAAGGTGAAGCAGGCGCTCAAGTGTGCCCGGTGCAGCAAGGTGCTGGACAGCGAGGAGCGGCTCGCCGTCCATATGCGGCTGCACACGGGCGAAAAGCCGTACAAGTGTTCGTACTGCGACAAGCGCTTCAATCACAAGAGCACGGTCAGCACGCACGAGAAGGCGGCCCACATTGCGGCCAACTCGTACCGGTGTGGCCGCTGCCACAAGACGTTCAACCAGAAGTGCCAGCTGCAGTACCACGAGAAGCTGCAGGAGGAGCACACGATCGCGTGCGAGCACTGCGAGAAGGTGTTTTGCTACAAGGCGAGCCACAAGGAGCACCTGTTTAAGGTGCACTTTCCGCGgccgaaaaagaaaacgcaGCGGAAGGGAGGCAGTCTGCGGGAGGGAgatgaacagcagcagcaggaatcGGGCACTGGCGGTGCAATGGCTGGGAGCAACGAAGGGGGTAATCAGGGCCGCAACAAGTTCAAATGTACCGTGTGCGATCGTCGGTTTTACTACGAGCGGGCGCTCGAGATGCATATGGGCGTGCACGATGCATCGCTGGACGTGAACGTGCTGTACTTTTCCTGCGACTACTGTCCGGAAACGTTCACCGAGGAGGagacgctgcagcagcacgagGCCCGCCACGTGGCCGACGGGACGACCGATTTCCGCGCAAACATGAAACGGGCCGAGGAAGGGGGAAACGCCACCACCGGGCACAGGTGTCCGCTGTGCTTTAAGCAGTTTGAGGATGAACCGTCCTTACGCGAACATCACCGTTCGCACCTGTGCCCATTTCCCGACTGTGCGCGGTGCGACCCAGTACGGCGCGATGATGCGTTCGACCTGACgcgcagtacgtacgatccggCGGACGATACgcaaccaacggtgtgtaacGTGTGCCATCGCGTACTGCCAACGTTCGAGGCGTACCAGAACCACTTCCACTACCATACGTCGCGCGTCCCGTTCTACTGCTACCACTGCCGGGAGGAGTTTAACGACAAGCGGGAGCTGTACAACCACACGCGGACGCATGCGCCTCGCGCACCGGAATCGTACACGTGCGAGGTGTGCGCGAAGGTGTTCTCGACCAAGGGGAACTTTAAGCGGCATCTGAAATCTCACGAAGCGGTCCGGGCGTTCGCGTGCGATCGCTGCTCGAAGCAGTACGACTACAAGAGTGCGCTCGAGGTGCATCTGAAGCGTTCGCACGGTATTGAGCTGTGA
Protein Sequence
MEYNNTYNKPYCGISQPTIPPAAAAVPGSSGFFPANDTAPSPFLKVPNPPYIKQETVPVGGESVIPGGTVTPPVNYSQDHHHYGTAGSYGEPGDVEKPPLFYRKAFDMPYMATPYVQSHLAQQFPQHLPSHPNQLPPHQHHAVHSQPVPHFQHQQQQQLLHHHQQPLAPLPTIVPSDMHSPQQLGPEQLQRAQPQQQHQQQQHPSSFHDYFDHLDPSSLEPYAYVLQKPAPPVPPIQPSETGSPLPASYPTASPVAPPAATPSPYTPLCEPPDSSKVRFKCETCPKSFDTKQKLEKHNRTHQPNGGAAGLEFKCRMCDKTFRTKSTLICHEKVHGESGLGSSCSCVECGKVFATEEKLQVHRRLHTGEKPYQCKVCLKCFNHQSNLIVHARIHDKVKQALKCARCSKVLDSEERLAVHMRLHTGEKPYKCSYCDKRFNHKSTVSTHEKAAHIAANSYRCGRCHKTFNQKCQLQYHEKLQEEHTIACEHCEKVFCYKASHKEHLFKVHFPRPKKKTQRKGGSLREGDEQQQQESGTGGAMAGSNEGGNQGRNKFKCTVCDRRFYYERALEMHMGVHDASLDVNVLYFSCDYCPETFTEEETLQQHEARHVADGTTDFRANMKRAEEGGNATTGHRCPLCFKQFEDEPSLREHHRSHLCPFPDCARCDPVRRDDAFDLTRSTYDPADDTQPTVCNVCHRVLPTFEAYQNHFHYHTSRVPFYCYHCREEFNDKRELYNHTRTHAPRAPESYTCEVCAKVFSTKGNFKRHLKSHEAVRAFACDRCSKQYDYKSALEVHLKRSHGIEL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00101103;
90% Identity
iTF_00095782; iTF_00101103;
80% Identity
-