Aaqu001040.1
Basic Information
- Insect
- Anopheles aquasalis
- Gene Symbol
- -
- Assembly
- GCA_002846955.1
- Location
- NJHH01001017.1:41006-67688[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.00055 0.034 14.1 4.0 1 23 247 269 247 269 0.97 2 11 0.0061 0.38 10.8 9.0 1 23 275 297 275 297 0.96 3 11 0.0001 0.0063 16.4 6.5 1 23 303 325 303 325 0.98 4 11 0.0003 0.019 14.9 2.3 1 23 331 353 331 353 0.95 5 11 4.6e-06 0.00029 20.6 0.7 1 23 359 381 359 381 0.97 6 11 6.5e-05 0.0041 17.0 0.1 1 23 387 409 387 409 0.96 7 11 5.1e-05 0.0032 17.4 1.3 1 23 414 436 414 436 0.97 8 11 0.0013 0.084 12.9 0.1 6 23 447 465 442 465 0.89 9 11 0.00029 0.018 15.0 0.1 1 23 553 575 553 575 0.97 10 11 0.0052 0.32 11.0 5.3 1 23 721 743 721 743 0.97 11 11 0.0044 0.27 11.3 4.9 5 23 756 774 748 774 0.92
Sequence Information
- Coding Sequence
- ATGTGTGCGGCACAGACCAACCCACCGTCCAACTTTAACTACGCCTGGGGCTATGGCGAGAACACGCGGGGTGAATCGGTGGTCGAGATAGCGCCCAACATTACCTACAATGTGGCAGCGGACGCATCCACGATGCCATACTTGCAGCTACCGGACGGTGCTAGTATAATAGTGCAGAAAGATGGCAAGGGAGCGATCACACACGGCAACAAAGCCGTCCGGCGGATGATCGTCGTAAACGATCCCTCTACGCTGCAACAAACTGGAACACAGCGaatcatcaccaccagtggtACAACGGCAACGGTCACAACGGGACATCAGAAGAAGCATGAAGTCATAACAAACGGAATCATCGAGACAAAGCCGAAAACGGCCATCCTGACGAcgggtgccggtggtgcattCATGTCCCCGATCGGACCGATACAGCTGACGGCGGAGGAATGCAACGATATCTTGATGAAgcgtgcggctgctgccgtcgccgccaacaaccaacaggccatcaccaacaacaccgatGGTCATCATGCATCCATCTCGGTGCAGGTGCAGAAGGTGATCCAGGGTCTGGAGGAAGGGGACGATTCGCAGGCCACCGCCACGACCCATCAGCTCAAGATTGAGCCAACGTTGAGCATTTCGCCGAAGCTAGAAGCGGTGGAGATTGATTACAATGATTACGTTCAGGAAGACACCACCCCAACGCCGAACGTGGTACCAAAGGAGCGTCCGTACTCGTGCGATCAGTGTGGTAAATCCTTCCTGTTGAAGCACCACCtcacaacacacgcacgcgTCCACACAGGCGAACGTCCGCATGTCTGCGTGCACTGTGGCAAGGACTTTGCTCACAAGCACTGTCTGAACacgcatctgctgctgcactcgacCGAACGACCGTACCAGTGTCAGGAGTGTAAGAAAAGCTTCACGTTGAAGCACCATCTGCTGACACATTCGCGAGTGCACTCGCGTGACCGGCCGTTTGTGTGCCAGGAGTGTGGTCGCTCGTTCCCGTTGAAGCGTCACCTGGTGACGCACAGTAAGTTCCATGCCGGTGAGCGACCGTACGTGTGTGAAGATTGCGGTGAAAGTTTCGCCCAAAAGGAGCATCTCGTAATGCACTCGCGGTTCCACGGTTCTGTCAATCCGTTCGTCTGCGCCGACTGTGGCGCTACCTTCCCGCGTAAGTTCCAGCTGGTGAACCATGGTAAACTGCACGGCCGCATACCGCACTCGTGTACGCTGTGCGGTAAAGAGTTCCTCCAGAAGCGCACCCTTGCGGCCCACATGAGGATCCACACCGGAGACCAGCCTTTTCCATGTATCGCCTGCGGTGAAGGATTCCGTACCAAGTCGGAACTGAACGCGCACAATCGGTTAACGCACGGTGGGGTTAATCCGAGTTCATCCAACACGACCATCATCACGACAAACACGGTCGTCACATCCAatgcccaacagcagcaacaacagcagcaaactcaGGCAcagggacagcagcagcagcagcaacagcacatcgaggttcagcagctgcagcaccaccagggccagcagcaacaggtacAGGATGTATCGAACGGGAACATTATCACGACGATCGCAACCACGGGGCAAGGTTCGCCCGATACGTCACCAAGGCCACAGTATGCCTGCCGGGAGTGTGGCAGTGCCTTTAACAGTCGCGAAGCGTTGGCCCTCCATCTGCGTTTGCACACCGGTGACAAGAGCCTGATGACGGATCTGTGCGCCCTGACAGCCGCCCTTCCCGGTCATCTATTCCCAGCTGTCAACCAAGAATATTCGATCACCCCTAATGGTGGCACGATCATGACGAGCAACTCTGTAATGCAAAACTCCCCTATTCCAGTACAAATTATCACCTCCTCGGGGCAAGTGGTACCGCAGATCCAACCTCAAAGCcctccacagcagcagcagcagcaacagcagcagcagcagcaccatcaacagcagctgcaacatCAGACACAGGTTgtacagcaacaccaaacgcAGACGGtagtacaacaacaacaaacccaacaacagcagcagcagcagctacagcagcaacaacaacaacagcagcaacaacagcaacagcagcagcagcaatccgttGTTGTatcgcaaacgaaaccaaaagcGCACGTCTGTCTCAGCTGCGGCAAAGGATTTGCCACCAAGCATGGTCTGTGTCTGCATAACAGGCGTCACCCGAACGGTGGCTGTACGGTTCGAACGCACGTGTGCGAGTGCGGTAAGGCGTTCTTCCAAAAGAACCATCTGATGTTGCACCAGCGTCAACATCTGGAGCAGAATCAGCGTGGCGCTACTGGAGCTACCGGTGGCAATGCCGCTGCCGGTcagcagacgcagcagcaacaggtgcaGGGTGCTggcggccaacagcaacagctggttgTGATTCAACAACCGAACCAGGAAGCACtggttcagcagcaacagcagcagcaggcagctcagcagcaacagcaacaagcggcagcacagcaacagcatcagcttcaacagcagcaacagcaagccgTTGCcgtacagcaacaacagaatcAACAGaacaatcagcagcacggCATGCGCAACCTTGTGATTGCGAATCAGCCCGTCCAGCTACAGGTGATGCAGGAGGGTAACGCGGCTCAAGTGATCAAGTACGAGATCATCCACGACACCTCGCGGCAATCGAATGTCGAGTGA
- Protein Sequence
- MCAAQTNPPSNFNYAWGYGENTRGESVVEIAPNITYNVAADASTMPYLQLPDGASIIVQKDGKGAITHGNKAVRRMIVVNDPSTLQQTGTQRIITTSGTTATVTTGHQKKHEVITNGIIETKPKTAILTTGAGGAFMSPIGPIQLTAEECNDILMKRAAAAVAANNQQAITNNTDGHHASISVQVQKVIQGLEEGDDSQATATTHQLKIEPTLSISPKLEAVEIDYNDYVQEDTTPTPNVVPKERPYSCDQCGKSFLLKHHLTTHARVHTGERPHVCVHCGKDFAHKHCLNTHLLLHSTERPYQCQECKKSFTLKHHLLTHSRVHSRDRPFVCQECGRSFPLKRHLVTHSKFHAGERPYVCEDCGESFAQKEHLVMHSRFHGSVNPFVCADCGATFPRKFQLVNHGKLHGRIPHSCTLCGKEFLQKRTLAAHMRIHTGDQPFPCIACGEGFRTKSELNAHNRLTHGGVNPSSSNTTIITTNTVVTSNAQQQQQQQQTQAQGQQQQQQQHIEVQQLQHHQGQQQQVQDVSNGNIITTIATTGQGSPDTSPRPQYACRECGSAFNSREALALHLRLHTGDKSLMTDLCALTAALPGHLFPAVNQEYSITPNGGTIMTSNSVMQNSPIPVQIITSSGQVVPQIQPQSPPQQQQQQQQQQQHHQQQLQHQTQVVQQHQTQTVVQQQQTQQQQQQQLQQQQQQQQQQQQQQQQQSVVVSQTKPKAHVCLSCGKGFATKHGLCLHNRRHPNGGCTVRTHVCECGKAFFQKNHLMLHQRQHLEQNQRGATGATGGNAAAGQQTQQQQVQGAGGQQQQLVVIQQPNQEALVQQQQQQQAAQQQQQQAAAQQQHQLQQQQQQAVAVQQQQNQQNNQQHGMRNLVIANQPVQLQVMQEGNAAQVIKYEIIHDTSRQSNVE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00097245;
- 90% Identity
- iTF_00092325;
- 80% Identity
- -