Basic Information

Gene Symbol
-
Assembly
GCA_030522585.1
Location
JAPYYQ010033631.1:1-587[-]

Transcription Factor Domain

TF Family
LRRFIP
Domain
LRRFIP domain
PFAM
PF09738
TF Group
Unclassified Structure
Description
LRRFIP1 is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'- AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA [1]. LRRFIP2 may function as activator of the canonical Wnt signalling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin [2].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.8e-16 2.1e-12 47.9 3.4 225 300 1 71 1 71 0.90
2 2 0.0092 1e+02 2.9 3.2 122 172 71 121 69 125 0.81

Sequence Information

Coding Sequence
ATGCGAAAGTTTGCGTCGGAAAAGAATAAACTGCGAGAAGAAAATCAACGTCTAACGCTAGAATTAGAAGAACTAAGAAATCAAATGAGGCCTGAACGACCCTCAAGTCCCGTGTTAGGTTTATCAGATTTAAAAGATGCTCAAAAAGAAGCCAACAAACTTCTAGCggattataaatttgaaatgcaAAAAGCGGAAAAAGATATGACAACTTTGCAAACAACTGTTTCGAGGTTGAAGAGTCGAATCATTCATTATCAATCTGAAGCTGaagcttttaaaaaagcagaaaatgaattaaaagttaaaaatgaaaagttacAAATGGAGcTGAAGGAATCACAAGGTCGAGTTGAAGAATTAGAAAATGCGAATTCTCACTTACA
Protein Sequence
MRKFASEKNKLREENQRLTLELEELRNQMRPERPSSPVLGLSDLKDAQKEANKLLADYKFEMQKAEKDMTTLQTTVSRLKSRIIHYQSEAEAFKKAENELKVKNEKLQMELKESQGRVEELENANSHL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00073727;
90% Identity
iTF_00073727;
80% Identity
-