Amin023146.1
Basic Information
- Insect
- Amiota minor
- Gene Symbol
- Hr39
- Assembly
- GCA_037043295.1
- Location
- JBAMAW010002525.1:1718986-1722626[+]
Transcription Factor Domain
- TF Family
- SF-like
- Domain
- zf-C4|SF-like
- PFAM
- AnimalTFDB
- TF Group
- Zinc-Coordinating Group
- Description
- The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 3 2.8e+04 -7.1 8.0 63 155 162 266 114 282 0.47 2 4 0.069 6.5e+02 0.1 5.8 52 175 333 474 307 484 0.72 3 4 2.8e-17 2.6e-13 50.8 6.4 1 134 557 707 557 718 0.69 4 4 1.6e-81 1.6e-77 262.4 0.2 188 408 729 940 719 940 0.93
Sequence Information
- Coding Sequence
- atgtcCACCatcaaaactgaaaacttCACCACAACAACTACAACGGCAGCCACAAGTGTGACATCAAccagtggtggtggtggctttCAATTACCAGTGAATATGAGCAATCATACAAGTATCTTAGGATCCAGTGCGGCGGCAGGATCTCCATTGACGACGACATCTACGACGACAACAACTCGGAATAATGTGTCTGTAACAAATATCAAGTGTGAAGTAGATGAAATGGTGACCGCGTCGAATGGCAATATAGTGCCAGTAATAGCGAATACGGGTAGCTATAACGGTGGGCAATCCACATTGATGACAGCATCAGGTGGCATCCGAATACCACTGACAAATGCCACTGCTAATGCTACACCAGcattaccaacaacaaaagccgAAGATTCTGATTCCGAGGCAGAACTGACAAACATTGAGAATTTCAAAGTAACACGGCGTGCCACAAGTAGTGCAAGTAATGCTGCTTCATCAGCCGCTGATACCCATAATAAGAATGGACCACGTCCAATGTCCTGGGAAGGTGAACTGTCCGAAACGGAAACAAATGAAGCTGAACTCATGGAGACGGAGAATTCTTTGAGTAACGGTTTGGGTGGCATCGTTGGAGTGGCGGTGATCAAAAGTGAAGCAACTACTACGACCACCTCTAGTGGCAGTCAACATATGCAGCCTATTAAAACAGAACTAGAACACATTTCTGCTAATATGTTCACAACGACAACGGCGACACCAACGCCTACACATGCGgccaaattgaaattggcCCCAACACAAAGTGATCCTATCAATCTCAAATATGAGCCCAGTTTGATAAGTGATATTATTGCTTCGTCTGCAGCGGGTTCAACGACAGCAACAGTGGTGTCTGGCGGTGGTGGTCTAAATTCACCGTTGCTGACGGGGCGCAGTAAATGCAATCAGTTGCCGTTGCCCGCGAATCCTAGTCCCGATTCCGCCATACATTCCGTTTATACACATAGTTCGCCATCACAATCTCCGCTGACGTCACGTCATGCACCCTACACACCTTCACTGAGTCGCAATAATAGTGATGCATCGCATAGTTCATGCTACTCTTACAGCTCTGAGTTTAGTCCAACCCATTCGCCCATTCAAGCGCGTCATGCTCCGCCAGCCGGTGCGCTATATCCGggaaattttaatggaggtgGTGGCAATGCCACAGGTGGATCTCTACATCATGGTGTGCTCTATAGACCCCTTAATATTGACTCAACTGTTGCTGGTTCCACAGCAGCAGCGAGTTGTATCAGTCAAGAAGCTCAAAATCTTAGCATGgatacaacaacaagcagCGGTTCCAGTGTGacgcaacagcaacagccaACATCGTCTAGTGGCTTTGAAccaggtggtggtggtggcagtaCATCTAGCAGCTTGCCTGCTTCACCGGCAGGTATTTCACGGCAACAGCTCATTAACTCGCCATGCCCGATTTGTGGCGATAAAATCTCTGGCTTCCATTATGGCATCTTCTCATGTGAGTCATGTAAGGGTTTCTTCAAGCGCACCGTTCAAAATCGGAAGAACTATGTTTGTGTGCGTGGTGGTCCGTGCCAGGTGAGCATCTCTACACGAAAAAAGTGTCCTGCCTGTCGTTTTGAGAAGTGTCTACAAAAGGGCATGAAACTGGAGGCCATACGGGAGGATCGTACTCGTGGTGGACGTTCGACTTATCAATGCTCCTACACATTACCTAATTCGATGCTTAGTCCATTGTTGAGTCCAGAACAACAGCAAGgagttgctgctgttgcagcagcagcagctgcggCAGTGGCTGCcaatcagcaacaacaacagcagcagcaacaacaccaacaacaacgtTTACATGCCCTCAATGGTTACAGTCAGTCACCAGTGTCGGGACATGGAAACAGCATAACAACGCAGACAATCAAATCAGAACAACAGGATCTAGGGGCGTATAATGGTGGCGCTGGAACGGCATCACCAGCAGTAACGCCAAATAACATCGCTGTTCCAGCTCTGCTGCAGCAAATTATGGATGTCGAACATCTCTGGCAGTATAATGATGCCGAACTGGCGCGCTTGAATCAACCACAAACCGCAACAAGTACAAGTTCCTCTGGAGGATCTCATAATTCTTCTGGTGGTGGTTGTGGTAATGCCAATACACCAATGACCAACCCACTGCTGGCCAGTGCCGGTCTTGGTTCAAATGGTGAAAACGCAAATCCCGATTTAATAGCGCATCTCTGCAATGTTGCCGATCATCGCCTCTATAAGATTGTCAAGTGGTGCAAAAGTTTGCCACTCTTCAAGCATATTTCGATCGATGATCAAATCTGCCTGCTCATTAATTCTTGGTGTGAATTGCTGCTCTTCTCCTGCTGTTTTCGTTCTATCGATACGCCGGGTGAGATAAAAATGTCACAAGGCAAGAAAATCACACTGGCTCAGGCCAAGTCGCATGGTCTACAGACCTGCATTGAACGTATGCTGAATCTGACAGATCATTTGCGACGCTTGCGTGTCGATCGCTATGAATATGTTGCTATGAAAGTTATAGTACTCCTTCAATCGGaCACCACTGAACTGCAAGAACCTGTTAAAGTTCGTGAATGCCAAGAGAAGGCTTTACAGAGCCTGCAAGCCTATACCCATGTCCATTATCCGGATACGCCGTCCAAATTTGGTGAACTATTGTTACGTATTCCCGATCTGCAGCGTACTTGTCAAATGGGCAAAGAGATGTTAACTATAAAATCACGGGATGGCGGTGATTTCAACTTATTGATGGAACTTCTCCGCGGAGAACATTGA
- Protein Sequence
- MSTIKTENFTTTTTTAATSVTSTSGGGGFQLPVNMSNHTSILGSSAAAGSPLTTTSTTTTTRNNVSVTNIKCEVDEMVTASNGNIVPVIANTGSYNGGQSTLMTASGGIRIPLTNATANATPALPTTKAEDSDSEAELTNIENFKVTRRATSSASNAASSAADTHNKNGPRPMSWEGELSETETNEAELMETENSLSNGLGGIVGVAVIKSEATTTTTSSGSQHMQPIKTELEHISANMFTTTTATPTPTHAAKLKLAPTQSDPINLKYEPSLISDIIASSAAGSTTATVVSGGGGLNSPLLTGRSKCNQLPLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGALYPGNFNGGGGNATGGSLHHGVLYRPLNIDSTVAGSTAAASCISQEAQNLSMDTTTSSGSSVTQQQQPTSSSGFEPGGGGGSTSSSLPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPEQQQGVAAVAAAAAAAVAANQQQQQQQQQHQQQRLHALNGYSQSPVSGHGNSITTQTIKSEQQDLGAYNGGAGTASPAVTPNNIAVPALLQQIMDVEHLWQYNDAELARLNQPQTATSTSSSGGSHNSSGGGCGNANTPMTNPLLASAGLGSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKHISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGKKITLAQAKSHGLQTCIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELQEPVKVRECQEKALQSLQAYTHVHYPDTPSKFGELLLRIPDLQRTCQMGKEMLTIKSRDGGDFNLLMELLRGEH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00062850; iTF_00061979; iTF_00062001; iTF_00061183; iTF_00061159;
- 90% Identity
- iTF_00061183;
- 80% Identity
- iTF_00062850;