Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.075 5.9 7.1 0.1 21 52 84 115 73 115 0.80

2 7 0.36 29 4.9 0.2 21 51 112 142 109 143 0.86

3 7 1.2 95 3.2 0.1 22 46 141 165 136 171 0.84

4 7 1.3 1e+02 3.1 0.0 21 45 168 192 164 195 0.90

5 7 0.057 4.5 7.5 0.0 21 50 196 225 192 228 0.86

6 7 3.5 2.8e+02 1.7 0.1 21 44 224 247 220 250 0.87

7 7 0.0037 0.3 11.2 0.1 20 45 251 276 239 282 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.075	5.9	7.1	0.1	21	52	84	115	73	115	0.80
2	7	0.36	29	4.9	0.2	21	51	112	142	109	143	0.86
3	7	1.2	95	3.2	0.1	22	46	141	165	136	171	0.84
4	7	1.3	1e+02	3.1	0.0	21	45	168	192	164	195	0.90
5	7	0.057	4.5	7.5	0.0	21	50	196	225	192	228	0.86
6	7	3.5	2.8e+02	1.7	0.1	21	44	224	247	220	250	0.87
7	7	0.0037	0.3	11.2	0.1	20	45	251	276	239	282	0.84

Coding Sequence: ATGGATGATATTTCTACAATAAAAGAAGAAAAAATCGAAATTATTGACGAATCAAAACCAGAATTCGACAATTTTGATCAGATGGACAAAATTGAAGAACATGAGGTGAATGCTGAATTTGAATTTAAAAAAGAAGAATTAGAATCTACAATAGATTTACCGAATTTTAAAATCGAATTTCAAGATTCTGATGAAGAATTAAATTCAGAGCGAGATTCAACAAAACAGGAACCGAGTTATAAAAATATTGCCGATAAATCTTTTAAATGTAAAATTTGTTCGAAATGTTTCACAAAATCCAGTAATTTAAAAAGTCATATTAGAATTCACACTAACGAAAAACCTTTTAAATGTGAAATTTGTTCGAAATGTTTCACAATATCCAGTCATTTAAAAGATCATATTAGAATTCACACTAAACAAAAACCTTTTAAATGTAAAATTTGTTCGAAATGTTTCACACGATCCGGTTATTTAAAAAATCATATTAAAACTCACACTGGAGAAAAACCTTTTAAATGTAAGAGTTGTTCGAAATGTTTCACACAATCCAGTATTTTAAAAAATCATATTAAAACTCATACTAACGAAAAACCTTTTAAATGTAAATTATGTTCGAAATGTTTCACACAATCCAGTACTTTAAAAAATCATATTAAAACTCACACTAACGAGAAACCTTTTAAATGTAAATTATGTTCGAAATGTTTCGCACGATCCGGTAGTTTAAAATGTCATATTAGAACTCACACTAACGAAAAACCTTTTAAATGTGAAATTTGTTCGAAATCTTTCACACAATCCGGTAATTTAAAATGTCATATTAAAACTCACACTAACGAGAAACTTTTTAAATGTGAAAATTGTTGA
Protein Sequence: MDDISTIKEEKIEIIDESKPEFDNFDQMDKIEEHEVNAEFEFKKEELESTIDLPNFKIEFQDSDEELNSERDSTKQEPSYKNIADKSFKCKICSKCFTKSSNLKSHIRIHTNEKPFKCEICSKCFTISSHLKDHIRIHTKQKPFKCKICSKCFTRSGYLKNHIKTHTGEKPFKCKSCSKCFTQSSILKNHIKTHTNEKPFKCKLCSKCFTQSSTLKNHIKTHTNEKPFKCKLCSKCFARSGSLKCHIRTHTNEKPFKCEICSKSFTQSGNLKCHIKTHTNEKLFKCENC

Sequence clustering based on sequence similarity using MMseqs2