Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 4.2 3.3e+02 1.5 0.3 21 47 43 69 32 82 0.77

2 7 0.1 8 6.7 0.1 20 45 98 123 89 130 0.82

3 7 0.5 39 4.4 0.1 20 46 126 152 122 158 0.83

4 7 0.0012 0.095 12.8 0.1 21 51 155 185 151 188 0.86

5 7 0.019 1.5 9.0 0.0 21 47 211 237 200 243 0.82

6 7 7.1 5.6e+02 0.8 0.0 21 44 239 262 236 266 0.86

7 7 0.01 0.79 9.9 0.1 21 48 267 294 259 294 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	4.2	3.3e+02	1.5	0.3	21	47	43	69	32	82	0.77
2	7	0.1	8	6.7	0.1	20	45	98	123	89	130	0.82
3	7	0.5	39	4.4	0.1	20	46	126	152	122	158	0.83
4	7	0.0012	0.095	12.8	0.1	21	51	155	185	151	188	0.86
5	7	0.019	1.5	9.0	0.0	21	47	211	237	200	243	0.82
6	7	7.1	5.6e+02	0.8	0.0	21	44	239	262	236	266	0.86
7	7	0.01	0.79	9.9	0.1	21	48	267	294	259	294	0.90

Coding Sequence: ATGAAAAAAGAAGAATTAGAATCTACAATAGATTTACCGGATTTTAAAATCGAATTTCAAGATTCTGATGAAGAATTAAATTCAGAGCGAGATTCAACAAAACAGGAACCGAATTATAAAAATATTGCCGATAAATCTTTTAAATGTAAAATTTGTTCGAAATGTTTCACACGTTTTTTTACTTTAAAAAGACATATTAGAACTCACACTAACGAAAAACCTTTTAAATGTGAAAATTGTTCAAAATGTTTCACACTTTTTGAATCATTAAAAAAGCATAATAGAACTCACACTAACGAGAGACCTTTTAAATGTAAAATATGTTCGAAATCCTTCACACAATCCATTATTTTAAAATCTCATATTAGCACTCACACTGGAGAAAAACCTTTTAAATGTAAATTATGTTCGAAATGTTTCAAAAAATCCTTTCATTTAAAATGTCATATTAGAACTCACACTAACGAGAAACCTTTTAAATGTGAAATTTGTTCGAAATGTTTCACACAATCCGGTAATTTAAAAAATCATATTAAAACTCACACTAACGAAAAACCTTTTAAATGTAAATTATGTTCAAAATGTTTCACACTTTTTGATACTTTAAAAAATCATATTAGAACTCACACTAACGAGAAACCTTTTAAATGTAAAATATGTTCGAAATCTTTCACACAATCCGGTCATTTAAAAAATCATATTAAAACTCACACTGGAGAAAAACCTTTTAAATGTAAATTATGTTCGAAATGTTTCACATATTCTGATAGTCTAAAAATTCATATTAGAACTCACACTAACGAGAAACCTTTTAAATGTGAAATATGTTCAAAAGATTTCACACATTCCAGTAATTTAAAAAAACACATTAGAACTCAACATTGA
Protein Sequence: MKKEELESTIDLPDFKIEFQDSDEELNSERDSTKQEPNYKNIADKSFKCKICSKCFTRFFTLKRHIRTHTNEKPFKCENCSKCFTLFESLKKHNRTHTNERPFKCKICSKSFTQSIILKSHISTHTGEKPFKCKLCSKCFKKSFHLKCHIRTHTNEKPFKCEICSKCFTQSGNLKNHIKTHTNEKPFKCKLCSKCFTLFDTLKNHIRTHTNEKPFKCKICSKSFTQSGHLKNHIKTHTGEKPFKCKLCSKCFTYSDSLKIHIRTHTNEKPFKCEICSKDFTHSSNLKKHIRTQH

Sequence clustering based on sequence similarity using MMseqs2