Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.67 53 4.0 0.3 24 46 136 158 123 166 0.81

2 7 3.1 2.5e+02 1.9 0.0 21 43 161 183 157 188 0.81

3 7 0.00077 0.061 13.4 0.0 21 46 189 214 184 220 0.87

4 7 0.064 5.1 7.3 0.0 21 47 217 243 214 249 0.85

5 7 2.3 1.8e+02 2.3 0.1 21 45 245 269 241 272 0.89

6 7 0.0035 0.28 11.3 0.0 21 46 273 298 269 304 0.87

7 7 3.9 3.1e+02 1.6 0.1 21 37 301 317 297 319 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.67	53	4.0	0.3	24	46	136	158	123	166	0.81
2	7	3.1	2.5e+02	1.9	0.0	21	43	161	183	157	188	0.81
3	7	0.00077	0.061	13.4	0.0	21	46	189	214	184	220	0.87
4	7	0.064	5.1	7.3	0.0	21	47	217	243	214	249	0.85
5	7	2.3	1.8e+02	2.3	0.1	21	45	245	269	241	272	0.89
6	7	0.0035	0.28	11.3	0.0	21	46	273	298	269	304	0.87
7	7	3.9	3.1e+02	1.6	0.1	21	37	301	317	297	319	0.85

Coding Sequence: ATGTTAAATATTTATAAAATAATTTTCCAAAATATTCCAACTGAAGAAAATTCCATAATGGGTGTTTCCAAAGAAAAAATAAAACCTGAAATTAAAATCGAACAAATTGAATTATTTAATCAATTTGGCGGGAAAAATAAGAAAGGCAGTATGAATATTTGTGCAATAAAAAACGAAAAAATGGAAATTATTGACGAATTAAAACCAGAATTCGACAATTTTGATCAGATGGAAAAAATTGAAGAACATGACGTGAATCTTGAATTTGAAATTAAAAAAGAAGAATTAGAATCTACAATAGATTTGCCGGATTTTAAAATCGAATTTCAAGATTCTGATGAAAAATTAAATTCAGAGCGAGATTCAACAAAACAGGAACCGAGTTATAAAATTATTGCCGATAAATCTTTTAAATGTAAAATTTGTTCGAAATGTTTCACACAATCCAGTCATTTAAAATGTCATATTAGAACTCACACAGGTGAGAAACCTTTTAAATGTAAGATTTGTTCGAAATGTTTCACAGAATCCGGTAAATTAAAAAATTATATTAAAACTCACACTAACGAGAAACCTTTTAAATGTAAATTATGTTCGAAATGTTTCACACAATCCGGTAATTTAAAAAGGCATATTAAAACTCACACTGGCGAGAAACCTTTTAAATGTAAAATTTGTTCAAAATATTTCACACAATCAAGTAGTTTAAAATTTCATATTAGAACTCACACTAACGAGAAACCTTTTAAATGTAATATTAGTTCGAAATATTTCACACAATCCTGTCATTTAAAAAATCATATTAAAACTCACACTGGGGAACAACCTTTTAAATGTAAGATTTGTTCGAAATTTTTCACAGAATCCGGTAAATTAAAAAGGCATATTAAAACTCACACTGGCGAGAAACCTTTTAAATGTAAGATTTGTTCAAAATGTTTCACACAATCCAGTACTTAA
Protein Sequence: MLNIYKIIFQNIPTEENSIMGVSKEKIKPEIKIEQIELFNQFGGKNKKGSMNICAIKNEKMEIIDELKPEFDNFDQMEKIEEHDVNLEFEIKKEELESTIDLPDFKIEFQDSDEKLNSERDSTKQEPSYKIIADKSFKCKICSKCFTQSSHLKCHIRTHTGEKPFKCKICSKCFTESGKLKNYIKTHTNEKPFKCKLCSKCFTQSGNLKRHIKTHTGEKPFKCKICSKYFTQSSSLKFHIRTHTNEKPFKCNISSKYFTQSCHLKNHIKTHTGEQPFKCKICSKFFTESGKLKRHIKTHTGEKPFKCKICSKCFTQSST

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00057178; iTF_00057395; iTF_00057028; iTF_00057110; iTF_00057491;
90% Identity: iTF_00057178;
80% Identity: iTF_00057178;