Basic Information

Insect: Agrotis exclamationis
Gene Symbol: Zfa
Assembly: GCA_950005045.1
Location: OX465423.1:8151358-8159935[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 23 0.0078 1.1 11.4 1.1 3 23 698 719 697 719 0.96

2 23 0.25 34 6.6 0.3 1 22 1103 1124 1103 1124 0.95

3 23 9 1.2e+03 1.7 0.4 1 22 1166 1187 1166 1189 0.82

4 23 0.02 2.7 10.1 4.8 2 22 1199 1219 1198 1219 0.93

5 23 2.6 3.6e+02 3.4 0.0 3 23 1228 1249 1226 1249 0.89

6 23 0.021 2.9 10.0 0.2 3 23 1270 1291 1268 1291 0.96

7 23 0.01 1.4 11.0 1.7 1 23 1297 1320 1297 1320 0.95

8 23 0.15 21 7.3 0.0 1 23 1346 1369 1346 1369 0.90

9 23 0.023 3.1 9.9 3.4 1 23 1374 1396 1374 1396 0.97

10 23 0.01 1.4 11.0 0.2 1 23 1402 1425 1402 1425 0.95

11 23 0.0048 0.66 12.0 0.8 1 23 1438 1460 1438 1460 0.97

12 23 0.00021 0.029 16.3 1.8 1 23 1510 1533 1510 1533 0.97

13 23 0.0021 0.29 13.1 1.3 1 23 1593 1616 1593 1616 0.96

14 23 0.0053 0.72 11.9 1.4 2 23 1643 1665 1642 1665 0.95

15 23 0.047 6.5 8.9 0.1 2 23 1671 1693 1670 1693 0.94

16 23 0.012 1.6 10.8 0.2 1 21 1737 1757 1737 1758 0.95

17 23 0.0005 0.069 15.1 1.0 1 23 1768 1790 1768 1790 0.93

18 23 0.00013 0.018 16.9 0.3 2 23 1883 1905 1883 1905 0.93

19 23 4.7e-07 6.5e-05 24.6 1.4 3 23 1912 1932 1911 1932 0.98

20 23 0.026 3.6 9.7 0.3 1 23 1950 1972 1950 1973 0.95

21 23 0.22 30 6.8 0.0 1 23 1996 2018 1996 2018 0.97

22 23 0.033 4.5 9.4 0.6 1 23 2024 2047 2024 2047 0.95

23 23 0.00031 0.042 15.8 0.4 1 23 2055 2078 2055 2078 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	23	0.0078	1.1	11.4	1.1	3	23	698	719	697	719	0.96
2	23	0.25	34	6.6	0.3	1	22	1103	1124	1103	1124	0.95
3	23	9	1.2e+03	1.7	0.4	1	22	1166	1187	1166	1189	0.82
4	23	0.02	2.7	10.1	4.8	2	22	1199	1219	1198	1219	0.93
5	23	2.6	3.6e+02	3.4	0.0	3	23	1228	1249	1226	1249	0.89
6	23	0.021	2.9	10.0	0.2	3	23	1270	1291	1268	1291	0.96
7	23	0.01	1.4	11.0	1.7	1	23	1297	1320	1297	1320	0.95
8	23	0.15	21	7.3	0.0	1	23	1346	1369	1346	1369	0.90
9	23	0.023	3.1	9.9	3.4	1	23	1374	1396	1374	1396	0.97
10	23	0.01	1.4	11.0	0.2	1	23	1402	1425	1402	1425	0.95
11	23	0.0048	0.66	12.0	0.8	1	23	1438	1460	1438	1460	0.97
12	23	0.00021	0.029	16.3	1.8	1	23	1510	1533	1510	1533	0.97
13	23	0.0021	0.29	13.1	1.3	1	23	1593	1616	1593	1616	0.96
14	23	0.0053	0.72	11.9	1.4	2	23	1643	1665	1642	1665	0.95
15	23	0.047	6.5	8.9	0.1	2	23	1671	1693	1670	1693	0.94
16	23	0.012	1.6	10.8	0.2	1	21	1737	1757	1737	1758	0.95
17	23	0.0005	0.069	15.1	1.0	1	23	1768	1790	1768	1790	0.93
18	23	0.00013	0.018	16.9	0.3	2	23	1883	1905	1883	1905	0.93
19	23	4.7e-07	6.5e-05	24.6	1.4	3	23	1912	1932	1911	1932	0.98
20	23	0.026	3.6	9.7	0.3	1	23	1950	1972	1950	1973	0.95
21	23	0.22	30	6.8	0.0	1	23	1996	2018	1996	2018	0.97
22	23	0.033	4.5	9.4	0.6	1	23	2024	2047	2024	2047	0.95
23	23	0.00031	0.042	15.8	0.4	1	23	2055	2078	2055	2078	0.96

Sequence Information

Coding Sequence: ATGAATGTGAACTATGATCGTGTTTGTAGACTGTGCTTGTCATCTCGAGGCGAATTACTGCCGATTTTTCCTACCACCAGTTCGGATGACTCGGAACCTCCCGTCCTCGCTTCGAAAATCAAGGATTGTGTGTCCGTACAGATAAACGAAAATGACGACCTGCCCACCAATGTCTGCAGGAAATGCATGGATAATGTCAATAACTggcatgtttttaaaaatgtatgtgAAAGGACACAAAACAAACTACTGTCTCTAAAAGATGGCAACCAACTAGAAGAGgtaaaaataaaaagtgaacCACTGTCTGATGAGGCTTATGATGATGGAGTGGTCATTGATGGCTCATATCCTGTCATTGAGAATGCTGGCTTTTCAAACAAACTGCAACCTGAAGGTCCCCCAATCTTGGCTTCATTGGGGCTCACACCAAGAAGTGATAAGAAATGTGTGGATCCAAGAATGGATTGGCACCGGGTCCATGCAATTTTGGACATGGTTCAAGAAGATGAGGTGATTGACTCTCTGCAGACAAGAGAAGAGTGTGATGTTCTGCAGCATTCTGACCATGACTCAGATACTGAAGCCGAACTCCAGACAGAAATTGATGATGGTTACGTTAATTCCAAAAGCGGATACATAtgcaaaaataaacaagttatgtCAAAAGTTCCAAAACTATCGACTTCTGTATATAATACTAGAGTAAAAGAAGCTTTCAAACTCAGAAAACGTAAATCAGAAGTTCGTAAACATTTGCCACGACCTAAAAATGCGTGGCAGTTGTTATTCACCGATGACCTACTAGAATTGATTGTTGCTTCTACTAATGACAATATTGTAACAAACGGGAAAAGTTTCACGGAGTCAACGAGCGTCAGCGAAATTAAAACGCTTATCGGTATTCTGTATCTGCACGGTATAATGCGGCCAACGCATCAGAAATGTATTGACCTTTGGAACAGTGAATGTGGTGTTCCTTGTGTCAGAAATGTCATGAAATACGAAAGGTTCAAATTCCTGCTTCAAAACATAAGCTTCGATAAAGAGGACGACGACAGCATAATACAGTTTGACATAATGAGGCGTATGCGCAAAGTATTCGAAATCTTCGCCATGAATTGCAGAACATCTCATGAGATCGAGAATATCGCAGTTATTGATGAGATCATTGTTCCAGTTTACGGACCTTGCCCATTTCGATACGATATTGATAAGAAGCCGCTGAAGCAGGGTATAAAAATGGTATTACTAGTTGATTCATCCACTTTCTATATGAGCAATTTAGACGTCATTACTGACGCTTACTTTGGCGCCGAGGAGATAACAAAAAAGTTGGTTCAGCATTTAGCTGGAACTGGCAGATCTATTGTGATGGACAGTTGGTTCACATCTTCATCACTGATGGATATTCTTAAAAATGAGTACCAGCTGTATTCTATTGCAGCCTTGAACCCAAACAGTGATATGATTCCGCCACTGTTCCTATCTCAATACAGGAAATGTCGAACATTCATGTCTGGATTTATTGATCATGAAGTATCACTGACATCGTATGTTAATACTGAGGGAAAGTCCGTAAACGTATTGACTAATGAACCTAGATATTACAGGAAAGGTCATATAAATCACACTACAGTTGTGTCAGTGTATAAAAAGAATCAGTCTGCAGTAGAAGTTGTGGATGTTCTCATGAGTTACTACACCACGATGCAACATACAAATGATTGGACTTTGTCTTTATTCTTTACTTTGCTAAACATTGCATCTGTTAACGCTCAAGTATTGTGGTGCTCTGAACACTCCAATGTTACTCAGCGTCGCTTATTCATTAAAGATTTGGCCCTCAGCTTACTAGAACCAGAAGAAAGGATGCTAATATCTCCAATTCACGATTTAgaggaaagaaaaaacaaattctCTCTTGGTGCGGAAAGTGAAAACAATGAAGAAGACGAGGAAGAAATGAACGAGCCGGCACAAAATTACCCGAAAATGCCCCACATGCCCGAGGTCTCCATCACGGTCATGAGGCCTACTGGTGAGACTCTACACGCTCGTCAAGGAATTCACCAACTCGCGTCCAAACTGTGCCTCGTGTGCGGTCGCTCCTATAGGTACTCTCACAACGCACGTAGACATGAACTTACTGCTCACAGTTTCGACAGatacacaaacaaaattacTCCTAAAAAAACCCTTAATCATCTACAACCCAAACTCAGACCAAACCCATTCAATCCCAAAGCACGGATGATGCCGAATCCTATTAGTCATAAGATGCAGTTCATGAATAAGAACATGCCAACAAAAATAATGCCCATGAACAAAGTTATCACGCCTCAGAAACCCATTCCAATAAAGACGTCGACAAAGACACAAAATAATTTGCCTTACCCTCTACGCATAAAAGCactcaaagatttacaaattaAGAAAAAGGAGCCTCAGATTCTGAAGACATTATTAACCTCCAAACCTGAAGTTCTGGTCTCAGAACCAGAAATCCTAAATTCTGGGCCTGAAAGTCCAGAGACATTGATATCCGAGCCTGAAATTGCATCTTTTCAAGTGGAAGCTATTCTTGCTGAGCCCGATGCCGATGCATACGATGATCCACAGCAAGGCGACGAAGAAGTCGATGAAGAAATGCAaaacaatcaaaatcaaaactatGATACAGTTGATATGGACTCTGAGAACGAAATAGAGATTGCTCGTCAGCAAAGTATTGAACAGGAGGGAGAGGAAAATGCTGATGGAGAAGAGAATGTGGACCATGATGACGATAATAACGTGGAAGGCGGTCAGAGCGAAAACGAGAAAGACGCTAATGACGATACTGCTGATAGTCAAGAACACatggaagaagaaaatagtGTTGATATTAAACCTGAAGATAATATAAAGGACGATGACGGCCAGGAGAGAGAACACGAAGAGGTAGGAATGAATCATAACGAAAACGAGGAAGAAGACGATGATGAGCTGCCAATGTCACTAGCCCCCGTCGTTGAAATAAGTGAGGGAATGCAAGGCGAGTCGTTTAATAGCGAAGTTAATGAAGAAGATGAGGAACTTGATGAAACTGTCGATCCCAATGATACCATTGAAAGTGAAGAGCAAGTTAAAGAACTAGACCCTGACAAAACATATGTTACAAAAACCCAAAGAGACTTCATCGAAAAGTACCGCGACATCATTCAACAAATTAACACGAAGCGTTGTTTATGTTGTGATAGAGAACATCCGCGCAGAAAAGCTGTTATACAACACTTGCAGAAAAACGGTCACAAGGTACCAAAACACACATGCTACAATTGTGTCATCACGTTTGGACATATTGGCGCACTACTCAGCCATATGAGGTCGAATTCTTGCACGAATTTGTGGAAGATTATTTACAATGAAAATGGCATAACCGACGACTTGGTCATCGAAGATGAACCAAAAGAGGTGAAGGTTGCATACAAAGATATTTTCAATGCCAGGTCATACGCTTGCAAACTGTGCCCAGCGAAATTCCAACTGAAACAATTTATAATGAAGCATGTTTTGGATACCCATGAAGATGGGCAGTCAAGGGTACCGCTCTGTTGTGTCCACTGCCGTTCTAGGTTTAAAGATAAGAGTTTACTTAAAAAACACATTCGTAAAGGTGATTGTACTGTATACATTGCCTGCGATTTGTGCTCCGAAAAGTTCGGAAACATGCAAGACTTCAACGACCATGCACTAGCCATCCACGCGGGCAGTTTTGATCAGACGGATAATCAGAGCAAATGTGTTGACGGTCGACCAACAGACTGTCCTTTATGTGGAAAGAAAAACAGCAGCTACCCGAATTTAGTGAAACATTTGAAGATTATACATGCGGTGGAGAAACCTCATTACTGTCAGCATTGTGACGCTAAATACGAACAAGCTACTGAGCTGAACGAACACATTTACATGGAGCACTCTGACAGAACATTAGGCATGCCGCCTGCTGAACCGGATATGTCCATTGTGAAAGAGGAAGCAGAGGAGTACCACTACTCTTGTACGGAATGTAATGCCATATTTGAAACTGTAGATGCGTGGACTGATCACCAAGTCGCTGAACATAACCAAGTGGCTCATCACTGCGATCAGTGTGAGAAGAAATTCCTTCGTCCTTCGGAGCTGGCAGAGCACAAGAACACGCACTTGCGGGTTAAATTTTATCCTTGTAGTGTGTGTCCGAACTCTTACAGCACGCCACAGAAACTGTCTGAGCATGTGCAACAGTCTCATCCTGGAATCGGTGCAGTCGCGGCAGCCGAGTCGGAATTCTTCTGTGACATTTGTATCAGAGCATTTAAAAGTCGCCAAGCGTACTCAAATCATATGCGTATTCACGCTAAAGTACCTACTACTAACAGGAAACCAGCTATAATTAAAGAGGGATTCGCGCCTCAAATTATTGGGAAACCCATCAAGCAGTATCCTATGGTTCAACCGGGTTTTGTATCGTTTAAACCTAATTACAACATCCCTAACGCTCCATATTCTTGTGACATTTGTGGTAAAGGATTCATGCATAAGAAAAATATATGGAAACATAAGAAAGTGTTACATGCTGATATTTTAGTTGATAGACATGATAGTGAAGAGAACACTATGCAAGCTTCCACAGAAGAGGATGAATTCAACCCGGACGAGAATGGTGCAGTACTCTCAACACCACAATTTAATAGTTTCAACTTTACGAATTTCCAGAACAGTGCTCAACAATCAACTCCAGAAACAATGCCATATTCGTGTGAATTATGTAGCAAACGGTTCCCGCTTAGAACCAGTTTGTGGAAACACAAGCGCGCTAAACACGGAATTGTTAACCCTGGCACTAGCGGCAGCAACGAGACATCCACACCATCCGCTAGTGGGGAAGGCAGTAGTAGATCTAGCTGCACTATATGCAGAATCACATTTGCAGACAAAAAATCTTACTATCGCCACCGAAAGAATGTGCACAAATCTACCGTTCAAATGTGCAAAATATGTGGTAAACCCCTAAGTTCAACTTTAGAATTATATGAGCACTTAAAAGCTGCTCATGCAAGGGAATTACTGGGATACAACGCTAACCAAGGCTCAAGTAAATCACAAGATGTGTCGCAAGAGATGGAACCCGATTATGAAAATGATCAAGAGTCTGTCGATCCCAGCGTTGATTACCAGGCGCGCTACCCTTGCGATACCTGTGGCAAACAATTTGTTGGGTTGCTAGCGTTGCAGAACCACCAGTGTATCAATCAGATACCATCTCAGCCACAGACGTTTGATTGTGAGATTTGTCACAAGAGTTACACTTCAATATCTGCACTAAAAAGCCATCGAGGTTGGCATTTACGTTCACCTGATGGAAAAGCAGCCGCTAACAATTCTGGCCTGTGGATGCCCCAGCACAAAGTTACAAGCAAGATAAGCAAACACGAGGTCATAGACCCGTCACAACTAGCTAAGGTTACACATACCTCCACTCCCCCACCTGTCTCTGCTACCGCAGCGAAAAGAAGACTGCCACCAGAGGTCGAGGTGACAGTCGTAAATCCGAATAAGAAATTGCGCTCAGACGACTCGGTCGACTTAGACATGCAAAATTCTGGAGCAATCGAGGATAGGTATTGCACTATTTGTGACAAGGAATTTACAAAAAGAGCGGCGTACCAGCGCCACATGGACGAGGTACATCAACCGAACTCTGTGTTCTGTCCGGTCTGTGATAAAAGTTTTACAAGGAAGTCCACACTGCTCATTCACATGAAGAAACATTACGAGAGCGGTGAGGGCAGCTCCTCTGCTACAGGTCAAGGGGACGATGATTACTCCTGTGATTTGTGCGGAGCTCAGTATGACAATGATCAGGCATTGAGAGCGCACCGAGCGCGGCACCACGGAGAAGAAGAAGAGTCGGCTGAAGAGAGTGATGACGGAAATGTTCCTATTGCTCCTCCCGGTGAATTCACATGTGCGCAATGTGGCGATGGTGTCGCTACGCCCAGGGACCTAATCGCCCATCGCACAATGCATGCTACTCCCACCAAATTCTTCTGTAACATATGCAAAGTGTACTTCGCTCGGGCGCTCGACCTTTCATCGCATACTCGTGCGCGGCACGCTGACAACGATAAGGTATTCTTCCCTTGTGCCATGTGCGACAGGTTTTATATGAACAAGAAGAGCTTACAGCGGCACATCGAGATGGCTCACTGA
Protein Sequence: MNVNYDRVCRLCLSSRGELLPIFPTTSSDDSEPPVLASKIKDCVSVQINENDDLPTNVCRKCMDNVNNWHVFKNVCERTQNKLLSLKDGNQLEEVKIKSEPLSDEAYDDGVVIDGSYPVIENAGFSNKLQPEGPPILASLGLTPRSDKKCVDPRMDWHRVHAILDMVQEDEVIDSLQTREECDVLQHSDHDSDTEAELQTEIDDGYVNSKSGYICKNKQVMSKVPKLSTSVYNTRVKEAFKLRKRKSEVRKHLPRPKNAWQLLFTDDLLELIVASTNDNIVTNGKSFTESTSVSEIKTLIGILYLHGIMRPTHQKCIDLWNSECGVPCVRNVMKYERFKFLLQNISFDKEDDDSIIQFDIMRRMRKVFEIFAMNCRTSHEIENIAVIDEIIVPVYGPCPFRYDIDKKPLKQGIKMVLLVDSSTFYMSNLDVITDAYFGAEEITKKLVQHLAGTGRSIVMDSWFTSSSLMDILKNEYQLYSIAALNPNSDMIPPLFLSQYRKCRTFMSGFIDHEVSLTSYVNTEGKSVNVLTNEPRYYRKGHINHTTVVSVYKKNQSAVEVVDVLMSYYTTMQHTNDWTLSLFFTLLNIASVNAQVLWCSEHSNVTQRRLFIKDLALSLLEPEERMLISPIHDLEERKNKFSLGAESENNEEDEEEMNEPAQNYPKMPHMPEVSITVMRPTGETLHARQGIHQLASKLCLVCGRSYRYSHNARRHELTAHSFDRYTNKITPKKTLNHLQPKLRPNPFNPKARMMPNPISHKMQFMNKNMPTKIMPMNKVITPQKPIPIKTSTKTQNNLPYPLRIKALKDLQIKKKEPQILKTLLTSKPEVLVSEPEILNSGPESPETLISEPEIASFQVEAILAEPDADAYDDPQQGDEEVDEEMQNNQNQNYDTVDMDSENEIEIARQQSIEQEGEENADGEENVDHDDDNNVEGGQSENEKDANDDTADSQEHMEEENSVDIKPEDNIKDDDGQEREHEEVGMNHNENEEEDDDELPMSLAPVVEISEGMQGESFNSEVNEEDEELDETVDPNDTIESEEQVKELDPDKTYVTKTQRDFIEKYRDIIQQINTKRCLCCDREHPRRKAVIQHLQKNGHKVPKHTCYNCVITFGHIGALLSHMRSNSCTNLWKIIYNENGITDDLVIEDEPKEVKVAYKDIFNARSYACKLCPAKFQLKQFIMKHVLDTHEDGQSRVPLCCVHCRSRFKDKSLLKKHIRKGDCTVYIACDLCSEKFGNMQDFNDHALAIHAGSFDQTDNQSKCVDGRPTDCPLCGKKNSSYPNLVKHLKIIHAVEKPHYCQHCDAKYEQATELNEHIYMEHSDRTLGMPPAEPDMSIVKEEAEEYHYSCTECNAIFETVDAWTDHQVAEHNQVAHHCDQCEKKFLRPSELAEHKNTHLRVKFYPCSVCPNSYSTPQKLSEHVQQSHPGIGAVAAAESEFFCDICIRAFKSRQAYSNHMRIHAKVPTTNRKPAIIKEGFAPQIIGKPIKQYPMVQPGFVSFKPNYNIPNAPYSCDICGKGFMHKKNIWKHKKVLHADILVDRHDSEENTMQASTEEDEFNPDENGAVLSTPQFNSFNFTNFQNSAQQSTPETMPYSCELCSKRFPLRTSLWKHKRAKHGIVNPGTSGSNETSTPSASGEGSSRSSCTICRITFADKKSYYRHRKNVHKSTVQMCKICGKPLSSTLELYEHLKAAHARELLGYNANQGSSKSQDVSQEMEPDYENDQESVDPSVDYQARYPCDTCGKQFVGLLALQNHQCINQIPSQPQTFDCEICHKSYTSISALKSHRGWHLRSPDGKAAANNSGLWMPQHKVTSKISKHEVIDPSQLAKVTHTSTPPPVSATAAKRRLPPEVEVTVVNPNKKLRSDDSVDLDMQNSGAIEDRYCTICDKEFTKRAAYQRHMDEVHQPNSVFCPVCDKSFTRKSTLLIHMKKHYESGEGSSSATGQGDDDYSCDLCGAQYDNDQALRAHRARHHGEEEESAEESDDGNVPIAPPGEFTCAQCGDGVATPRDLIAHRTMHATPTKFFCNICKVYFARALDLSSHTRARHADNDKVFFPCAMCDRFYMNKKSLQRHIEMAH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00017541;
90% Identity: iTF_00758469;
80% Identity: -