Basic Information

Gene Symbol
-
Assembly
GCA_963924505.1
Location
OZ004669.1:13146706-13157654[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 23 0.005 0.33 12.0 1.1 3 23 207 228 206 228 0.96
2 23 0.19 12 7.0 0.3 1 22 609 630 609 630 0.95
3 23 2.3 1.5e+02 3.6 0.6 1 23 672 695 672 695 0.87
4 23 0.02 1.3 10.1 0.5 3 21 706 724 704 725 0.94
5 23 0.4 26 6.0 0.1 3 23 734 755 732 755 0.89
6 23 0.011 0.7 10.9 0.2 3 23 775 796 773 796 0.96
7 23 0.26 17 6.6 2.6 1 23 802 825 802 825 0.93
8 23 0.11 7.3 7.7 0.0 1 23 851 874 851 874 0.90
9 23 0.017 1.1 10.3 3.4 1 23 879 901 879 901 0.97
10 23 0.016 1 10.4 0.2 1 23 907 930 907 930 0.95
11 23 0.00094 0.061 14.3 1.3 1 23 943 965 943 965 0.98
12 23 0.0013 0.085 13.8 4.0 1 23 1013 1036 1013 1036 0.96
13 23 0.00032 0.021 15.8 3.0 1 23 1094 1117 1094 1117 0.96
14 23 0.0011 0.07 14.1 2.0 3 23 1144 1165 1142 1165 0.95
15 23 0.079 5.1 8.2 0.1 2 23 1171 1193 1170 1193 0.93
16 23 0.009 0.58 11.2 0.2 1 21 1239 1259 1239 1260 0.95
17 23 0.0011 0.072 14.0 0.6 1 23 1270 1292 1270 1292 0.93
18 23 0.0001 0.0065 17.3 0.3 2 23 1383 1405 1383 1405 0.93
19 23 3e-07 1.9e-05 25.3 1.4 3 23 1412 1432 1411 1432 0.98
20 23 0.046 3 9.0 1.0 1 23 1451 1473 1451 1474 0.93
21 23 0.17 11 7.2 0.0 1 23 1496 1518 1496 1518 0.97
22 23 0.0083 0.53 11.3 0.4 1 23 1524 1547 1524 1547 0.95
23 23 0.00023 0.015 16.2 0.4 1 23 1556 1579 1556 1579 0.96

Sequence Information

Coding Sequence
atgaatgtGAATTATGATCGTGTTTGTAGACTGTGCTTGTCATCTCGAGGCGAATTACTGCCGATTTTTCCTACCACCAGTTCGGATGACTCGGAACCTCCCGTCCTCGCTTCAAAAATCAAGGATTGCGTGTCCGTTCAGATATCCGAAAATGACGACCTGCCAACGAATGTGTGCAGGAAATGCATGGAAAATGTCAACAACTGGCACATTTTTAAGAAAGTGTGTGAAAGGACAcaaaacaaactacattctctGATTAAAAAGGATGGAAGCCAACTAGAAGAGgtaaaaataaaaagtgagCCTTTGTCTGATGAAGCTTATGATGATGGAGTGCTGATTGATGGTTCATATCCTGATTTAGAGAATGCTGGCAGTTCAAGTAAAAACCAGCCGGAGGGCCCACCAATCTTGGCTTCGTTGGGCCTCACACCAAGGAGTGATAAGGGGTTGGAGAGTGATAAAGATGAGGAAGAAGCGGAAGAAGAGATGAACGAATCTGCCCCATCATTCTCAAAAGTACCCAACATGCCAGAGGTGTCTATCACTGTTATGCGTCCCACTGGAGAAACCCTACAATCTCGTCAAGGCATTCAGCAGCTAGCGTCCAAGGATTGCCTGGTCTGCGGCCGTACGTATAGATACTCACACAACGCCAGGCGACATGAACTCACCGCTCATAGCTTTGACAGATACACTAACAAAATTACTCATAAAAAGTCACATTCACATATGCAACCTAAACTTAGACCAAATCCATTCAACCCTAAAGCGCGATTGATGCCCAACCCCATCAGCCATAAAATGCAACTCTTACCAAAGGCCAGACCGATAAGAATAATGCCTCAAAAAATAATATCCCCACCGAAACCTATACCTATAAAACAACCTAAAGCACCGCAAAACAATTTGCCGTACCCTCTTCGAATTAAAGCATTGAAAGACTTGCaaataagaaagaaagaacCCCAAATTCTCAAGACACTGCTAACTTCAAAACCGGAAGTCTTAGTTTCTGAACCTGAGATTGTTAATTCGGCTCCAGAAAGTCCGGAAACATTGATATCTGAGCCGGAAATAGCATCTTTCCAAGTTGAAGCTATCTTATCTGAGCCGGATGGCTACGACCAGCAACAAGGCGATGAAGTTGATGGCGAAGTGCACAATAATCAGAACTATGATACACTTGACATGGATTCTGAAAATGAAATAGAGATCGCTCGTCAGAAAGAAAATGAAACTGAAGAAGATGAAAATATTGAACAAGacgccgaagaaaagatggaacACGACGGTGATGAAAACAACGTTGATGACAACGTAAATGATGAAAAAGAGCCTATCGAAGACGAAGGTGATACAGAAGAAGTAGACCACGCCAACGTCAAAGATGATTATGTTGATGATGAGACTAAAGCAGTCGAAGATTGTAATGATGAACATGAAAATGAAGAACAAGATATTAACCAAGACGAAAATGAAGAAGATGACGAGGAACTCCCACCGATGGGTATAGCTCCGGTTGTTGAAATTAATGAAGATATGCAGACCAACTCTTACAACAGTGAAATGAACGAAGACGAGGAAGAAGATGTTGATGAAACAGTGGACCCCAATGATACTGTAGACGGTGAAGACACTGTCAAAGAACTTGACCCTGATAAATTGTATGTAACAAAGACTCAGAAGGAATTTATTCTAAAATATCGCGATATCATCGAACAGATAAACACGAAAAGATGTCTGTGTTGCGATAGAGAACACCCTCGTAGAAAAGCTGTTATTCAGCATTTACAGAAAAACGGACACAAAGTCCCCAAACATACATGCTATAACTGTGTGATCACATTTGGTCATATAGGCGCTTTACTCAGCCACATGAGATCCAATACATGCACGAATTTgtggaaaataatttacaacgAAAACGGTATAACCGACGATTTAGTTATCGAAGATGGGCCAAAAGACGTCAAGGTTCAGTACAAAGACATATTGAATGCCAGATCCTATTCTTGCAAATTGTGTCCAGCGAAATTCCAGTTAAAACAGTTTATAATGAAACATGTACTAAATGTTCATGAAGATGGTCAATCTATGGTGCCGCTAGCATGTGTTCACTGTGGTTCCAGGTTTAAGGAAAAGGCTACATGGAAAAAACACATTCGTAATGGTGACTGTACAGTTTATATTGCTTGCGATTTGTGCGAAGAGAAATTCAAGAATATGCAAGCTTTCAATGACCACGCTTTAGCTGTACACGCCGGCAGCTTCGACCATGATAGTCAAAGCAAATGCGTCGATGGACGACCAACCGACTGTCCTCTTTGTGGGAAAAAGAACGCCACTTATCAGAATCTgataaaacatttgaaaattattCACAATGAAGAGAAACCCCATTTCTGCAAGCATTGTGATCTCAAATTTGAGTTAACTGCTGACTTAGATAACCACATATTTATGGAACATTCTGATATGAGTCTTGGTGTTCACAATACCGAGCCCGACATGTCACTTGTGAAAGAAGAGGCAGAAGAATATCATTACTCATGTACAGAATGTAATGCCATATTCGAAACGGTAGACGCTTGGACTGACCATCAAGTAGCTGAGCATAACCAAGTAGCTCATCACTGCGACCAATGTGAAAAGAAATTTTTACGACCTTCTGAACTTGCTGAACACAAGAACACACACTTGCGTGTCAAATTCTATCCTTGCAGTGTATGCAGTAATTCTTACAGTACTCCTCAGAAACTATCTGAGCATGTGCAACAAGTACACCCGGGAGCCGGAACGCAAGCTGCTGTAGATTCAGAGTTTTACTGTGACATATGTATCAGGTCTTTCAAAAGCCGTCAAGCGTACTCCAACCATATGCGTATACACGCTAAAGTTCCTACCACTAACAGGAAGCCGGGTGAACCTAAAGGATTCGCACCACAGATAATTGGTAAGCCGATTCAAAAGTTCAATATGGCACAACAAGGTTTCGTTTTCAAACCAAATTGTAACGTACCTAATGCTCCTTACTGCTGTGACATATGTGGTAAAGGTTTTATGCACAAGAAAAATATCTGGAAACATAAGAAAGTTTTGCACGCTGATCTCCTTAATGACAGAAATGACAGTGAGGAGAATACTATGCAGGCTTCTACTGAAGAGGATGAATACAACATTGATGAAAATGGTGCTGTATTATCTACACCTCAGTTTGACAGCTTCAATTTCACCAGCTTTGCAAACAGTACGCCTCAATCGCAGCCAGAAACCTACACTTGTGATATCTGCTACCAGCGATTCTCATTTAGAGACAGTTTGAGGAAACATAAGCGTGCTAAACACGGAGTTATAAATGCCAGTGCTAGCAGTAGCTCAGAAACGCAGACGCTCGCGCCTCAAAGCGATGGCTCGAGGTCTAACTGCACTATTTGTAAGATTTCGTTTTCGGACAAAAAGTCTTACTATCGCCACAGGAAGAATGTTCATAAATCGACGGCTCAGATGTGTAAAATATGTGGCAAACCTCTAAACTCTACATTAGAACTGTACGAGCATCTGAAAGCTGCACATGCACGGGAACTCTTGGGTTACAACGCAAACCAAGGTTCAAGTAAATCTACAAGTCAAGAAGTAGCCCAAGAGATGGAAATGGAATACGAAGGGGATCAAGATTCTGTCGATCCCAGCGGGGACTATCAAGCTCGATACCCCTGTGACACATGCGGGAAACAATTTGTTGGACTGCTAGCATTGCAGAACCATCAGTGTATATCAACTCTCGCATCCACACCTCAAACGTTTGACTGTGAAATATGTCACAAGAGCTATACATCTATAGCTGCGTTGAAAAGTCACCGCGGTTGGCATTTAAGATCGCCAGATGGAAAGGCGGCCGCCAATAATACCGGTCTATGGATGCCTCAGCACAAAGTGACAAGCAAGGTCAGTAAACACGAGGTCGTCGATCCGTCACAGCTCGCTAAAGTCACACATTCGACCCCAGTGACCACTACTACTAAGAGGAGACTGCCACCCGAAGTCGAAGTCACGGTAGTAAATCCAAATAAGAAGATGCGTTCAGACGACTCATTCGAAATGGACCACCAAAATAACCAAACTGGCGGGCTTGAAGACCGATACTGTACGATATGCGACAAGGAATTCACGAAACGGGCGGCATACCAGCGCCACATGGATGAAGTGCATCAACCCAATTCCGTGTTTTGCCCTGTGTGTGACAAAAGTTTCACACGAAAATCGACTTTGCTGGTCCATATGAAGAAGCATTACGAAGGTGGAGAAGGAAGTTCCTCTACCACTGGCCAATTGGAAGATGAATTACATGCATGCGATCTCTGCGGGGCTCAGTATGATACTGCACAAGCGTTGAGGTCCCATCGAGTGAGGCACCACGGCGAGGAATCTGAGCACGAGTCGGACGATGACGGCAACATAAATCTAAGCCAACCGGGTGAATTTACCTGCGCACAGTGTGGCGACGGAGTGGCCACGCCGCGCGATTTGATCGCCCACCGCACAATGCATGCCACTCCCACCAAGTACTTCTGTAATATTTGCAAAGTTTATTTCGCTAGAGCTATAGATCTCTCATCACACACTCGGGCAAGGCACGCTGAGAGTGAGAAAAGTGCAATGTTCCCCTGTGCCATGTGTGATCGCTTTTATATGAATAAGAAGAGCTTGCAGCGCCACATAGAGATGGCCCACTGA
Protein Sequence
MNVNYDRVCRLCLSSRGELLPIFPTTSSDDSEPPVLASKIKDCVSVQISENDDLPTNVCRKCMENVNNWHIFKKVCERTQNKLHSLIKKDGSQLEEVKIKSEPLSDEAYDDGVLIDGSYPDLENAGSSSKNQPEGPPILASLGLTPRSDKGLESDKDEEEAEEEMNESAPSFSKVPNMPEVSITVMRPTGETLQSRQGIQQLASKDCLVCGRTYRYSHNARRHELTAHSFDRYTNKITHKKSHSHMQPKLRPNPFNPKARLMPNPISHKMQLLPKARPIRIMPQKIISPPKPIPIKQPKAPQNNLPYPLRIKALKDLQIRKKEPQILKTLLTSKPEVLVSEPEIVNSAPESPETLISEPEIASFQVEAILSEPDGYDQQQGDEVDGEVHNNQNYDTLDMDSENEIEIARQKENETEEDENIEQDAEEKMEHDGDENNVDDNVNDEKEPIEDEGDTEEVDHANVKDDYVDDETKAVEDCNDEHENEEQDINQDENEEDDEELPPMGIAPVVEINEDMQTNSYNSEMNEDEEEDVDETVDPNDTVDGEDTVKELDPDKLYVTKTQKEFILKYRDIIEQINTKRCLCCDREHPRRKAVIQHLQKNGHKVPKHTCYNCVITFGHIGALLSHMRSNTCTNLWKIIYNENGITDDLVIEDGPKDVKVQYKDILNARSYSCKLCPAKFQLKQFIMKHVLNVHEDGQSMVPLACVHCGSRFKEKATWKKHIRNGDCTVYIACDLCEEKFKNMQAFNDHALAVHAGSFDHDSQSKCVDGRPTDCPLCGKKNATYQNLIKHLKIIHNEEKPHFCKHCDLKFELTADLDNHIFMEHSDMSLGVHNTEPDMSLVKEEAEEYHYSCTECNAIFETVDAWTDHQVAEHNQVAHHCDQCEKKFLRPSELAEHKNTHLRVKFYPCSVCSNSYSTPQKLSEHVQQVHPGAGTQAAVDSEFYCDICIRSFKSRQAYSNHMRIHAKVPTTNRKPGEPKGFAPQIIGKPIQKFNMAQQGFVFKPNCNVPNAPYCCDICGKGFMHKKNIWKHKKVLHADLLNDRNDSEENTMQASTEEDEYNIDENGAVLSTPQFDSFNFTSFANSTPQSQPETYTCDICYQRFSFRDSLRKHKRAKHGVINASASSSSETQTLAPQSDGSRSNCTICKISFSDKKSYYRHRKNVHKSTAQMCKICGKPLNSTLELYEHLKAAHARELLGYNANQGSSKSTSQEVAQEMEMEYEGDQDSVDPSGDYQARYPCDTCGKQFVGLLALQNHQCISTLASTPQTFDCEICHKSYTSIAALKSHRGWHLRSPDGKAAANNTGLWMPQHKVTSKVSKHEVVDPSQLAKVTHSTPVTTTTKRRLPPEVEVTVVNPNKKMRSDDSFEMDHQNNQTGGLEDRYCTICDKEFTKRAAYQRHMDEVHQPNSVFCPVCDKSFTRKSTLLVHMKKHYEGGEGSSSTTGQLEDELHACDLCGAQYDTAQALRSHRVRHHGEESEHESDDDGNINLSQPGEFTCAQCGDGVATPRDLIAHRTMHATPTKYFCNICKVYFARAIDLSSHTRARHAESEKSAMFPCAMCDRFYMNKKSLQRHIEMAH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

90% Identity
iTF_00027991;
80% Identity
-