Apis007246.1
Basic Information
- Insect
- Acyrthosiphon pisum
- Gene Symbol
- -
- Assembly
- GCA_005508785.1
- Location
- NC:93311266-93322765[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 6.1 3.1e+02 2.1 0.0 7 21 131 145 126 146 0.88 2 14 0.069 3.5 8.2 5.1 1 23 180 202 180 202 0.96 3 14 0.0015 0.073 13.5 1.7 1 23 208 230 208 230 0.98 4 14 8.8e-06 0.00044 20.5 1.7 2 23 236 257 235 257 0.97 5 14 0.0056 0.28 11.6 0.1 2 20 264 282 263 284 0.91 6 14 0.0015 0.075 13.4 1.3 2 23 304 325 303 325 0.95 7 14 2.1e-07 1e-05 25.6 4.1 1 23 355 377 355 377 0.99 8 14 2.3e-05 0.0011 19.2 1.6 1 23 383 405 383 405 0.98 9 14 0.00046 0.023 15.1 8.5 1 23 411 434 411 434 0.98 10 14 0.015 0.73 10.3 3.5 1 23 444 467 444 467 0.97 11 14 3.4e-05 0.0017 18.6 1.0 2 23 729 750 728 750 0.97 12 14 8.2e-06 0.00041 20.6 0.7 1 23 756 780 756 780 0.98 13 14 0.00068 0.034 14.5 0.3 2 23 788 809 788 809 0.97 14 14 0.00026 0.013 15.8 1.0 1 23 815 837 815 837 0.98
Sequence Information
- Coding Sequence
- ATGGACGATCAACTAGATATTATGTTGGAAAATACCAATGAGGAATTTGTTACCTTATCGTATGCTGATCATTCATTGATCTCTCATCCCGAACAATTATCTGATGAGTGTGCAGACATGAttttaaaccagGATGATTGTCAAAATATGAGTGCCATGGCTCCATTAAACGATTTGTTATTgggacaaacatttttaatagagACTAACGAACAACCATTATTTGTAGATGACACAGAGTTAATTACATTCCAACATATTGACCCAAACGGACAAATAAATGATATCGAgactatttcaaataatattgaatctgATAAATCTAcgattgaaaatattgattttactataaattctGATGATCACTTCCAAGAAATTTGTACAGATTTTAATAAAACCACTAATGACAGTAATAATTTGACAGAACATTTACAAGTTAAGATAAACACTGATATAACTAGTGGGAACTACAGTTATTCAACTgctattaaaattttagatgATGTCGCTAAAAGTCCTGTTGATACTAATgGTCATTTTGTTTGTGATTTATGCTTACATGAATTTTACAACTGGAAACATTATAAGAAACATAAACTAGAACATTTAAATGATAAACcgtttaaatgtttgaaatgtttaaaatcatttaattacaATaataattatttacttcacATTGCTTCTCATTCAacaagtaatttaaaatgtccaaaatgtaaaaaagaatttaaacgCTATGCTAGCTTTAAAGCACACctgaaaattcataaaactgAAGAATTAATTACATGCAATATTTGTGACAAGATATTTGACAATCAGtatcgATTGGATATTcataaagaaaattgtatacaagaAAATTTAATGAATCCTAGTGAAGAAACATCTGTTGGTTGTATTAAAACTTGTACAATTTGCAATATGTCTTTTTCAACTGTATCAGAATATAAAATGCACAACAAAGAACATAGAAAAtttgattcagtgttgaaaaaatatcataaacttgctacaaaattcaaaaaattacataaaacggctaataaaattaaaaaatttaaatgtgatCATTGTGATTGGTCATTTAATAAGTCAAATCTTTTACGCCGACATATGAGAACGCATACTGGTGAAAAACCATTTGAAtgcACGGATTGTTCAGTATACTTTACTCAACAAAACTCATTAAATAGACATCTGATGAAACATAAAGGAATACGACCATTTAGATGTGAATTCTGTGAAATGAGTTTTTGTCAAAAAGgtcatttaattaatcatatgaAAAAATGTCATGCTGTTAAAAAAGAACCAACAAGAATTCATAAATGCTCTATGTGTTCATGTGTTTACAACAGCATCAATGCTCTTAacagacatttaaatattttccatgGAGTGAAAACTAGAAATGTACACAAAAAGGTTCAAAATAAAGTAACAAAGAGCGTAGAAACAGTTGATGAAAATAAACATTCTATTAaagattcctCAAAGTTAGAACAATGGCTTGAAGAAGTAGCGCATGAATTGCAAAGTGGTGATAATAATACAGagttaaagaattGCAATGACTCAATTACTACGCAATGTGAATTCGGATTAAATTTGATTGAAAGTGAACACTATGATCACATTTTAAGCCCGATTTCTAATATAGCTAGTGATCACACTGAAATTGAAAACTTGACATATTCTCTTGCagatggtgataactatattattgttgtgaagAAGAAACAAGAGCAACCATCAATCAAAAATGCTGTTGTTCAAAaccaagAAAAGGAACTACTAACAACTGTCACTGAAAATGAATCAATATCACTAAATGTTGTAAAAGAAACTGCTAAAAAGggAATGAAACCTATAACAACTGCTACTAAAAATGAATCAATACCATTAAGTGTTGTAGAAGAAACCACTACCACTAAAAAGCTTccttcaagaaaaaaaaaatgtgggaatAAAATGTCTAAATTGGATGCAAAAAAGATTTTaccaagaaaaaaaaatgtgagttcattaaatttgaaaaagaaGAATTGTGTCAGTAATGAAATTAAGAGAAATATAACTCATCCAAGTAGTAAAGCTGAGCCAAAAgttgtatatgtacctaatatagctAATTCAGAAGAAAGAACCATTAGTATTaCGGAAAAGCCATTGCCAAAAGTGTGTCAATTCTgtgagaaaatatttaaaaagaatgcCGATCTCGAAAGACACGAAAGAACACACACTGGTGACAAACCTTATAAATGCGACGAACAGGATTGTAATAAAGCATTTGCCACTAAGAGTTCACTTGAATATCATAAAATCACCCATTCAGGTCAGATGAAACGAGCAGAGTGTCCCCAGTGTAATGGATTATTTGCTACAACGTCAACTTTGAAAGTTCATATGCGACAACACACAGGTGAAAAACCATTTAAATGTCCTGTATGCGGTGATGCATTTCGAACAACTGGACACTTACATACACATGTGATAATACATGAACGAAAAAAGAAacgcaaataa
- Protein Sequence
- MDDQLDIMLENTNEEFVTLSYADHSLISHPEQLSDECADMILNQDDCQNMSAMAPLNDLLLGQTFLIETNEQPLFVDDTELITFQHIDPNGQINDIETISNNIESDKSTIENIDFTINSDDHFQEICTDFNKTTNDSNNLTEHLQVKINTDITSGNYSYSTAIKILDDVAKSPVDTNGHFVCDLCLHEFYNWKHYKKHKLEHLNDKPFKCLKCLKSFNYNNNYLLHIASHSTSNLKCPKCKKEFKRYASFKAHLKIHKTEELITCNICDKIFDNQYRLDIHKENCIQENLMNPSEETSVGCIKTCTICNMSFSTVSEYKMHNKEHRKFDSVLKKYHKLATKFKKLHKTANKIKKFKCDHCDWSFNKSNLLRRHMRTHTGEKPFECTDCSVYFTQQNSLNRHLMKHKGIRPFRCEFCEMSFCQKGHLINHMKKCHAVKKEPTRIHKCSMCSCVYNSINALNRHLNIFHGVKTRNVHKKVQNKVTKSVETVDENKHSIKDSSKLEQWLEEVAHELQSGDNNTELKNCNDSITTQCEFGLNLIESEHYDHILSPISNIASDHTEIENLTYSLADGDNYIIVVKKKQEQPSIKNAVVQNQEKELLTTVTENESISLNVVKETAKKGMKPITTATKNESIPLSVVEETTTTKKLPSRKKKCGNKMSKLDAKKILPRKKNVSSLNLKKKNCVSNEIKRNITHPSSKAEPKVVYVPNIANSEERTISITEKPLPKVCQFCEKIFKKNADLERHERTHTGDKPYKCDEQDCNKAFATKSSLEYHKITHSGQMKRAECPQCNGLFATTSTLKVHMRQHTGEKPFKCPVCGDAFRTTGHLHTHVIIHERKKKRK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00942088; iTF_01032360; iTF_00184791; iTF_01038665; iTF_01167903;
- 90% Identity
- iTF_00942088;
- 80% Identity
- -