Basic Information

Insect: Acronicta leporina
Gene Symbol: br
Assembly: GCA_947256265.1
Location: OX366513.1:10557368-10559042[+]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 4.4e-28 1.4e-25 90.0 0.4 1 108 22 125 22 127 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	4.4e-28	1.4e-25	90.0	0.4	1	108	22	125	22	127	0.93

Sequence Information

Coding Sequence: ATGAATAATGCACCGCAGTTCTCTTTACGCTGGAATAATTACGTATCTCACGTAACAGAAGCGTTTAATGTTCTCCGTTTTGAAAATGATTTAGTGGATGTAACGCTCTGTTGCGATGGAGGTAAAATTAAAGCACACAAAATGTTATTGTCCGCCTGTAGTAGTTACTTCAAGCAGATATTCAAAGAGAACCCATGTCAACATCCTGTGATTATATTCAGAAACTTCAAGTTCGAAGACCTGAATGCGATTATCAATTTTATGTACCACGGTGAGGTGAACATATTCCAGGAACAATTGGAATCATTCCTTATAACTGCTGAGTTACTAGAGGTTAAGGGTTTGACTGATAACATAGAGGATGAATCATCTAAAAGCCAGTTGAGAATCACAGATAACACCTCTTTAGATTTAAGTTCTAAATCAAGTAGAATTTCTGAAGATATTGTGCCTGTGTTATCTGAAGAACCAATTAATTTAGCGACAATGCAGACTTCTAGAGAAGAGTACATTCCACAGCCAATCACTATGAAAAGTATTCCAGATCAAGAAAATGGCAATATTGAAATGCAACCTGAAACTTCAAAGTCTGATGATAATACAAAATTGAAAACAACACCATCTACTGGTGAAGAGATGCAAGTTGACACCCAATCAACTTCAGCTGAAGATTTATCTGAAAAAAGCAATTCAGAATCAGAGCTGGCAAAGTTCCGCTGCCAACTGTGTCCAAAAGGTTTTAAGCATCCCACTTCATTGACATTGCACAAGGATTCACATGCAGGAAAGACACAGTGTCCTGTTTGTCACCGGTCATTCTCACGATCTTATGACATGAGGAGTCATTTGCAAAGAATACACCAAGGAAAGCAACTGACCATCAAAGAGATCAGATATAAGAACACAAATGACAGTGTTGCTCCCAAGCAGTTCACTCACCATATTTAG
Protein Sequence: MNNAPQFSLRWNNYVSHVTEAFNVLRFENDLVDVTLCCDGGKIKAHKMLLSACSSYFKQIFKENPCQHPVIIFRNFKFEDLNAIINFMYHGEVNIFQEQLESFLITAELLEVKGLTDNIEDESSKSQLRITDNTSLDLSSKSSRISEDIVPVLSEEPINLATMQTSREEYIPQPITMKSIPDQENGNIEMQPETSKSDDNTKLKTTPSTGEEMQVDTQSTSAEDLSEKSNSESELAKFRCQLCPKGFKHPTSLTLHKDSHAGKTQCPVCHRSFSRSYDMRSHLQRIHQGKQLTIKEIRYKNTNDSVAPKQFTHHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00017797; iTF_01265409; iTF_01077102; iTF_01264817; iTF_01076661; iTF_00007618; iTF_00007242; iTF_01252364; iTF_01251960; iTF_00186754; iTF_00186403; iTF_01488163; iTF_01222090; iTF_01487828; iTF_00327191; iTF_01221724; iTF_00327485; iTF_00859619; iTF_01358988; iTF_00860019; iTF_01359352; iTF_00925347; iTF_00071625; iTF_00924909; iTF_00071929; iTF_00831364; iTF_00908049; iTF_00831742; iTF_00908414; iTF_01094180; iTF_00745924; iTF_01095081; iTF_01093259; iTF_01095470; iTF_01093654; iTF_01094525; iTF_00178341; iTF_00178785; iTF_00809669; iTF_00809296; iTF_00810613; iTF_00810239; iTF_01117478; iTF_00449738; iTF_01117873; iTF_00449304; iTF_01312327; iTF_01312668; iTF_01416967; iTF_01417346; iTF_00364520; iTF_01527465; iTF_00364170; iTF_01526634; iTF_00037387; iTF_01527886; iTF_01526201; iTF_00037949; iTF_00038302; iTF_00039390; iTF_00038975; iTF_00036960; iTF_00290826; iTF_00787799; iTF_00788151; iTF_00291165; iTF_00819690; iTF_00819298; iTF_01062954; iTF_00041025; iTF_00928834; iTF_00042788; iTF_00044070; iTF_01534406; iTF_00041927; iTF_00446729; iTF_01063338; iTF_00040395; iTF_01065163; iTF_00042252; iTF_00301709; iTF_00302670; iTF_01532238; iTF_01533199; iTF_01535056; iTF_01084401; iTF_01084753; iTF_00043698; iTF_00301330; iTF_00446354; iTF_00040019; iTF_01062005; iTF_00041398; iTF_00445718; iTF_01062358; iTF_00712471; iTF_00447384; iTF_00712056; iTF_01064792; iTF_01533560; iTF_01535449; iTF_00445338; iTF_00043099; iTF_00302267; iTF_01532638; iTF_00447776; iTF_00929184; iTF_01534080; iTF_01363563; iTF_01363241; iTF_01441227; iTF_01441553; iTF_01440594; iTF_01440215; iTF_01416012; iTF_01416391; iTF_00122957; iTF_00122545; iTF_00758774; iTF_00124795; iTF_00124414; iTF_00758398; iTF_00761807; iTF_00762182; iTF_00785647; iTF_00785322; iTF_01119503; iTF_01119854; iTF_00274864; iTF_00274544; iTF_00784016; iTF_00783655; iTF_00932049; iTF_00931587; iTF_01064241; iTF_01063879; iTF_00072210; iTF_00072366; iTF_00111794; iTF_00112142; iTF_00121586; iTF_00121968; iTF_00274066; iTF_00273739; iTF_01030738; iTF_01030370; iTF_01362514; iTF_01362723; iTF_00018291; iTF_00018630; iTF_00173203; iTF_01247245; iTF_00120657; iTF_00121011; iTF_01247670; iTF_00173783; iTF_00668055; iTF_00667672; iTF_00341843; iTF_00341455; iTF_00001620; iTF_00001293; iTF_00238324; iTF_00237890; iTF_00450293; iTF_00450625; iTF_00685941; iTF_00685588; iTF_00973909; iTF_00974247; iTF_01085525; iTF_01085921; iTF_01193237; iTF_01192848; iTF_01437205; iTF_01437580; iTF_00429526; iTF_00429158; iTF_01339062; iTF_01339562; iTF_01430390; iTF_01430054; iTF_01538902; iTF_01539239; iTF_00375447; iTF_00375862; iTF_00425975; iTF_00425581; iTF_00820567; iTF_00820214; iTF_01260247; iTF_01260617; iTF_00622968; iTF_00623634; iTF_00784824; iTF_00784522; iTF_01286040; iTF_01285683; iTF_00345945; iTF_00346355; iTF_01083481; iTF_01083854; iTF_00374778; iTF_00374342; iTF_00724058; iTF_00724374; iTF_00850906; iTF_00851305; iTF_00933210; iTF_00932777; iTF_01118458; iTF_01118849; iTF_01362138; iTF_01361776; iTF_00123836; iTF_00123508; iTF_00148092; iTF_00147650; iTF_00428636; iTF_00428267; iTF_00726940; iTF_00726587; iTF_00869788; iTF_00870177; iTF_00968156; iTF_00968436; iTF_00906301; iTF_00906673; iTF_00000798; iTF_00000452; iTF_00185758; iTF_00185442; iTF_00907166; iTF_00907498; iTF_01173406; iTF_01173799; iTF_00172351; iTF_00171970; iTF_01340767; iTF_01340351; iTF_00012131; iTF_00012550; iTF_00013638; iTF_00013197; iTF_01342339; iTF_01342625; iTF_00772145; iTF_00772501; iTF_00177309; iTF_00177693; iTF_00281508; iTF_00281906; iTF_00282965; iTF_00282555; iTF_01316900; iTF_00113766; iTF_00112615; iTF_00112971; iTF_01317421; iTF_00113422; iTF_01316498; iTF_01317844; iTF_00114204; iTF_00114556; iTF_00467504; iTF_00468277; iTF_00467834; iTF_00468602; iTF_00709381; iTF_00709796; iTF_00858695; iTF_01010514; iTF_00859091; iTF_01010908; iTF_00064091; iTF_00063722; iTF_00942951; iTF_00824328; iTF_00824005; iTF_01565225; iTF_01564804; iTF_00707466; iTF_01502220; iTF_01502581; iTF_00707104; iTF_01152300; iTF_01152675; iTF_01361196; iTF_01198285; iTF_01360816; iTF_00823157; iTF_00441654; iTF_00442070; iTF_01197911; iTF_00823550; iTF_00674768; iTF_00674408; iTF_01425232; iTF_01425583; iTF_00008146; iTF_00008520; iTF_00889746; iTF_00889377; iTF_00027379; iTF_00026982; iTF_00027891; iTF_00028324; iTF_00795318; iTF_00794792; iTF_01027862; iTF_01027473; iTF_00952324; iTF_01231171; iTF_01230762; iTF_00888813; iTF_00888400; iTF_00953136; iTF_01026897; iTF_01029397; iTF_01031255; iTF_00952825; iTF_01026458; iTF_00951963; iTF_01028444; iTF_01031582; iTF_01028831; iTF_01029760; iTF_00050073; iTF_00050435; iTF_00383833; iTF_00384200; iTF_00677786; iTF_00678136; iTF_01075994; iTF_01075638; iTF_00852294; iTF_00300779; iTF_00851949; iTF_00300376; iTF_01341434; iTF_01341837; iTF_01492506; iTF_01492136; iTF_01401819; iTF_01401411; iTF_00994460; iTF_00994839; iTF_00637054; iTF_00636636; iTF_00637822; iTF_00638276; iTF_01436638; iTF_01436237; iTF_01444030; iTF_01444349; iTF_00355327; iTF_00355750; iTF_00807263; iTF_00806842; iTF_01167232; iTF_01166849; iTF_00908993; iTF_00405548; iTF_00405141; iTF_00909376;
90% Identity: iTF_00237890;
80% Identity: iTF_00017797;