GCFC
- Domain
- GCFC domain
- Group
- Unclassified Structure
- PFAM
- PF07842
- Desciption
- This entry describes a domain found in a number of GC-rich sequence DNA-binding factor proteins and homologues [4, 5], as well as in a number of other proteins including Tuftelin-interacting protein 11 [1]. While the function of the domain is unknown, some of the proteins it is found in are reported to be involved in pre-mRNA splicing [1, 2]. This domain is also found in Sip1, a septin interacting protein [3].
- Rederence
-
- Isolation and characterization of post-splicing lariat-intron complexes. Yoshimoto R, Kataoka N, Okawa K, Ohno M. Nucleic Acids Res. 37, 891-902, (2009).
- NTR1 is required for transcription elongation checkpoints at alternative exons in Arabidopsis. Dolata J, Guo Y, Kolowerzo A, Smolinski D, Brzyzek G, Jarmolowski A, Swiezewski S. EMBO J. 34, 544-58, (2015).
- Identification of septin-interacting proteins and characterization of the Smt3/SUMO-conjugation system in Drosophila. Shih HP, Hales KG, Pringle JR, Peifer M. J. Cell. Sci. 115, 1259-71, (2002).
- Identification of a novel component C2ORF3 in the lariat-intron complex: lack of C2ORF3 interferes with pre-mRNA splicing via intron turnover pathway. Yoshimoto R, Okawa K, Yoshida M, Ohno M, Kataoka N. Genes Cells 19, 78-87, (2014).
- Pax3/7BP is a Pax7- and Pax3-binding protein that regulates the proliferation of muscle precursor cells by an epigenetic mechanism. Diao Y, Guo X, Li Y, Sun K, Lu L, Jiang L, Fu X, Zhu H, Sun H, Wang H, Wu Z. Cell Stem Cell 11, 231-41, (2012).
Statistic of Transcription Factors
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Transcription Factor Table
| Gene ID | Insect | Gene Name | Gene Symbol |
|---|---|---|---|
| iTF_00000352 | Abrostola tripartita | Atri014319.1 | STIPL1 |
| iTF_00000353 | Abrostola tripartita | Atri020683.1 | PAXBP1 |