Basic Information

Insect: Zophobas morio
Gene Symbol: -
Assembly: GCA_027724725.1
Location: JALNTZ010000003.1:31743497-31754948[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 1.7e-14 1.8e-10 41.4 0.2 6 70 223 285 219 290 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	1.7e-14	1.8e-10	41.4	0.2	6	70	223	285	219	290	0.85

Sequence Information

Coding Sequence: ATGGACGAAGAAAAAAAGGAACGGGAACGGTCGAAGTCTCCTGATGGCAGTAACCCAACTAGTGAGGAACCTGTGGAAAAAGCCGACGTAAATGGTGAAGGTGAAAATCGAGACATTAGCGAAACAAGTGTAGATGAGACTGTTGCTAACCCGGTTGCGAATTCTCCAGACGAGCTAGCGAAAGAAAGCGTCGAAAAATCAGATGATTTTGTAGCCGACAAATCCAGGTCGAAGAAGCGGAAAGCAAGTGAGGCTAAAGTAGGGGACGAAAGCGCTTCAGAAGAGAGCGTTAGCGACATAAAAGACACACAGTTACAAGATTCAATAAACGTGAAGGCCGACAAAGATGACTCTTCTGCAAATGAATCGTCATCAGATTTGAACATACCCCCAAAACAAACGTTAGGTAAAGGAAAAAGGGCCCGAATTCCTAATAAACGTTACAGCGATATTTTATTATCACCGCAACCACGTTCACACAAAACTAACCTTGAAAACGGTGACAAATATGAGAAGTACGAAAAGATCGAACCTGAAAATGACATCTTTAACACAAAAGATGACGAAATTGCGAGTTTACCGAACGTTACGTCTCTCAAGTCGAGGTCAAATACCAGCAGTCCAGCTGCCAAACGACTGAAATATTCCACAGATGTTACAGATCCCAAATATCGCAAACCATTTGTGTATGGTTGGAAACGAGAATTAGTATATAGGGCGACGTCTGATAATCCAAATAAACGAAATGGGGATATTTATTATTATACGCCGACGGGGAAAAAGGTTCGTTCCATGAGGGAAGTTTCAGAAAACTTGAAAAACAAAGAATTAGCTTTGGAAAATTTTACGTTTTTCAAAGAACCTTTAGGTTTAGATGACCCTGAAAAAGAAATTATTCGTGATGCAAAGGCGTGGAACAAGAAAGTGATGCCGAAAACAGGTTCAAAAACTCCAAGAGTTTTAAGTCCGAAAGTGAATAGTCCAAAAGTTTCAAGCACACCAAAGGCAACAAAAATCACTAGTCCGAAAGTTGCTCCAACGCCGGCTGAGACTTCTGTGGAACCGGCTACAACGAGGACCAAAGCATCTACTCGCAGCTTCGAAAATCTTAAGGTTAAGTTGCCTCCCAGCAAAAGTAAAGCAGAGAAAAAGGCCAAGGTGGAAAAAGAACCCATGGAAGTCGACTCACCGCCCACAAAACGAGCCGCCAACAAGAAGACCCCAGCGAAAGTAACCCCAAATGTAGAAATGGAGGGCAAACCGTGCCAACCATGTTCGATTCGATGCCAAGGTGTTTTGGGTATGGTACCTACTCTTCAATGTCGACTTTGCCTATGTCTCTACCATTACGAGTGTGTTGGATTATCACCGCATGTGCAGATACAGGAATACGTCTGCAAGAACTGTCGACTGGAACATGGTCAGAACGTCGCAACATCCGCGTCAATCGTTCTGCCGCCCCTCACCCCCATTAACACCTTGAAATCAATGACGACACAGTCGACAGTCTTGCCAACATTGCAACGCATACCGCCTGACTCACCTCAACCAGAAGCGACAACTCCTGGCGGTGTGCCGAACATGCCCCGTCTGCTTCCTTTACCCAAAGTTGCTAAAGACGCGCCCCCACCACTAAAACCGACCAAAAACAACCCCCAGAACATAACCGAAACGAAAAGTTTGGTCGGTTCGGTGACCTCGTGGTTGCCGCATAGTTCAACCATCCAAGTTGACAATATGCAGAGGAATAAAGAGAACGAGCCCGCGGAGGCTCCAAGACCACAGTACGTTGAATATTTAGCTGGTAGGAAATTTTTAATTATTCCGAAACACAATGTCGTTTCGGTGTCGCCGACGAGTGTACCTAGTAAGCAAAAACAGCTGAACTTTATTGAGAATGACTGTGTTAGTAACGATGAAGTAAAAGACGAACTATCGTCGCCTAAACGTGTTCAAAGTGGTACTACTGAAAGGACAGACAGTGTGGTGGGGGCTACTGATGAGGTAGTTACTGATAGAAGTGAAGAAAATCGTGCTGATGAAGATAGACCAGAAACGGTTGAGTCTCCAAGGGCGAAAAGACGTGCTGTTAGATCGAATAATGTTGTGTCAAATGACAAACATGAAGAACCGAAATTTATGGACAGTTATCTTCAGAATTTGTCGTATGGTTACAATACGCTTTTGTACGTTTTTCAGTACCTTAAAGTGCAAGATTTGTTAAGAGCAGGGTGTGTGTGTACTATGTGGCGGGATATAGCAAGTCATCCGTCGTTGTGGCGAACGGTGCGCATGAAGAATTCGCAAGTTCATAGTTTTGAAGGTTTGGCGAATAGTCTTCAAAAACATGGTACTGTACATCTTGATCTAAGGAAGATGCTGTTGCCGACAAATGGAGGGGATGATATTTGGCCTGAGTTTTCCAAAGCTATCCAAAAAGTGCAAACTCTACGCAAAATTGAATTGTGCAGGTGTCCGGCATCTGTTGTGGAGCAACTGGCCGTAACCAACAAAGATTTGGAGGTGATAAATGCCGTCACAATCAAATGTGAAAGCATGAGTCTCGATATGTTATCATCACTAAAAAATCTAAAAGAATTACGATTGAAGTCAACCAGTGGATTGACGTTATCTTCTGATATTACTTCGTTAAAAGAGCTAACAAACTTAACTCATTTATCGCTCACCTCTATTAAAGACCTTAACAAGATGAACCTCCAGGTGATTGCAGCATTAAAGAGTCTCGAATCGTTGGATCTTGGTGAATGTAGTGACTTTCCGGCTAATTTCGGAGAAGATATTTTAACAAAATTAAAAAATCTTGAGAAGCTAAGGCTAGAGAAAGGACAGGGTAATTGCCATACGTTCGAAATATTGGATGCAGTGAAACAAATGCCTCATTTAGAACAGTTGGAATTGGTTAATTTTGACATCAAAAGTGGGTTTGATGTGGCTTTAGGAGGATGCAGGAATATAAGAAAGTTGTTGATTATTCCTACGTATATTTCTCAAAGTGCTACAACAAACCATATGGTGCTGGGTGGTGTTCTAAGACTGCAAAGTACGCTGTCACATTTCGTGTGGGGAGTTACTTTAGAATTGTTGCGTGTTACCGAATTGTTTGTTGATCAGTGTGAAGACCCAGATAAGAAAGAGAAAAAAGATAAGAAACCTGTAGGGAATGGTGACAGCATTCCTGTTTTGAAACCTGTACCTTTGATTACGGACAAAAACGATACAATACCTCCAGCCCATGATCCACCGCAAGTGGAAATTCTCCCACTACCTAATCTTCAGAAATTGTTGTTGCAGAGTTTACCAACGACAAGAGTTAAGATTCTCAAAATTCCTTTTCATGCCACCTGGCGGCAGAGTATTACTGATACGGTTAATTAA
Protein Sequence: MDEEKKERERSKSPDGSNPTSEEPVEKADVNGEGENRDISETSVDETVANPVANSPDELAKESVEKSDDFVADKSRSKKRKASEAKVGDESASEESVSDIKDTQLQDSINVKADKDDSSANESSSDLNIPPKQTLGKGKRARIPNKRYSDILLSPQPRSHKTNLENGDKYEKYEKIEPENDIFNTKDDEIASLPNVTSLKSRSNTSSPAAKRLKYSTDVTDPKYRKPFVYGWKRELVYRATSDNPNKRNGDIYYYTPTGKKVRSMREVSENLKNKELALENFTFFKEPLGLDDPEKEIIRDAKAWNKKVMPKTGSKTPRVLSPKVNSPKVSSTPKATKITSPKVAPTPAETSVEPATTRTKASTRSFENLKVKLPPSKSKAEKKAKVEKEPMEVDSPPTKRAANKKTPAKVTPNVEMEGKPCQPCSIRCQGVLGMVPTLQCRLCLCLYHYECVGLSPHVQIQEYVCKNCRLEHGQNVATSASIVLPPLTPINTLKSMTTQSTVLPTLQRIPPDSPQPEATTPGGVPNMPRLLPLPKVAKDAPPPLKPTKNNPQNITETKSLVGSVTSWLPHSSTIQVDNMQRNKENEPAEAPRPQYVEYLAGRKFLIIPKHNVVSVSPTSVPSKQKQLNFIENDCVSNDEVKDELSSPKRVQSGTTERTDSVVGATDEVVTDRSEENRADEDRPETVESPRAKRRAVRSNNVVSNDKHEEPKFMDSYLQNLSYGYNTLLYVFQYLKVQDLLRAGCVCTMWRDIASHPSLWRTVRMKNSQVHSFEGLANSLQKHGTVHLDLRKMLLPTNGGDDIWPEFSKAIQKVQTLRKIELCRCPASVVEQLAVTNKDLEVINAVTIKCESMSLDMLSSLKNLKELRLKSTSGLTLSSDITSLKELTNLTHLSLTSIKDLNKMNLQVIAALKSLESLDLGECSDFPANFGEDILTKLKNLEKLRLEKGQGNCHTFEILDAVKQMPHLEQLELVNFDIKSGFDVALGGCRNIRKLLIIPTYISQSATTNHMVLGGVLRLQSTLSHFVWGVTLELLRVTELFVDQCEDPDKKEKKDKKPVGNGDSIPVLKPVPLITDKNDTIPPAHDPPQVEILPLPNLQKLLLQSLPTTRVKILKIPFHATWRQSITDTVN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00752970; iTF_00415115; iTF_01410000;
90% Identity: -
80% Identity: -