Basic Information

Gene Symbol
-
Assembly
GCA_028554725.2
Location
CM053023.1:13509362-13519365[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.00029 0.039 15.5 1.3 1 23 147 169 147 169 0.98
2 16 5.1 6.8e+02 2.1 5.9 1 23 175 198 175 198 0.95
3 16 0.0053 0.7 11.5 1.3 2 23 437 458 436 458 0.97
4 16 4.7 6.2e+02 2.2 4.1 1 23 464 487 464 487 0.94
5 16 0.19 25 6.6 2.2 1 23 515 538 515 538 0.95
6 16 0.037 4.9 8.9 2.9 2 23 584 605 583 605 0.96
7 16 0.064 8.4 8.1 2.8 3 23 841 861 840 861 0.96
8 16 0.0077 1 11.0 0.7 1 23 867 890 867 890 0.96
9 16 6.7 8.9e+02 1.8 0.1 2 23 927 949 926 949 0.94
10 16 0.025 3.4 9.4 0.3 1 23 963 986 963 986 0.96
11 16 2.6 3.4e+02 3.1 0.1 1 20 1184 1203 1184 1205 0.92
12 16 0.0015 0.2 13.2 9.0 1 23 1237 1259 1237 1259 0.99
13 16 0.00026 0.034 15.6 3.9 1 23 1264 1286 1264 1286 0.98
14 16 0.004 0.53 11.9 6.8 1 19 1292 1310 1292 1315 0.93
15 16 0.002 0.27 12.8 0.1 2 19 1321 1340 1321 1344 0.92
16 16 1.7e-05 0.0023 19.4 4.4 1 23 1350 1373 1350 1373 0.98

Sequence Information

Coding Sequence
ATGGACGCTGATACCGCACTGGAAAGAACGGCGCCAACGGATTACAGGCTCGTTTGTAGAACGTGCCTTGCTTCGGATGCAGAATTTTACAAACTCGACTCACCTCTTTTCTTGGAAGATGATGATAGTGACCAAAAACCAGTGAGCTTTATGGAATGTTTGCGTTACTGTACACGTTTAGTTGATAACgatgaaagtgaaaatttagaatttccaacatatatatgtactgaaTGCAGTGCATCTCTGCAAGTGTCctacaatttcataaaaaatgcacTTGAAGCGCATGAAATTTTACGACAAAAATTGAGCGAAAATTCTGAACAGCAGCAGAGAAAATGCAAAGTACAGCGCAAGAATGGCGTTATTGGCGAAAATGGGTGCAAAAGCGCGGGGTTGGAAGATGGTGTGGATACGGAAGCGACGAAAATGCGTTTTCGGTGTAAAATATGCAACGAGAAAGTCGAAACAAAGAAAACATTAAAAGAACACATCAAATTGCATTTAGATATAATTTCTTATTGCTGTGAACTGTGTAGTTTCGAATGCAAGAAACGTACTTTGCTATTTGATCATTATAAGTTGGCGCATAACATGCAACCAACGCGGGATCAGTTAAAACCGAAAACCAAGCAACCTGTAAAAAAAGAGCATAGCGATAGCGAAGATCCAATTTCGCAAGAAATGGAGAAAATACACAATACACAAATAAATGATGAGTATATGCCTAATACACAATACGCGGTAACGGAACAACAAGAAGACTTAGATATGAAGCTATTTCTAACACCTGCCAGTAGTAATGCATCAGCGGCATATGTGGAAGCGGCTGCAGCCGCAACTGCTATTGATGTACCCACTGACACGCACGAGCATAGAACCAGCATAACAAAGGATTTGCAGCAATACGGCACAGACCAATTCAATATAACCGCAAATGAATTGAGTGTGGGCAATGAATTTATCGTTATGGCGGATGGTACGGTGGAGGAAGTAATGGGCAACGGTGTTGTCATCGAGTACATAAATGCGGCGGATGATGGTGTAACATTGGAAAACGGTTTGGTATTGGATAACATTATGCAAGTACAACCAACAGGCGATGCCGATCAGGCAGTGACTATGGATATGGATGTTGATGATATTATAATTGAAGAAGGTGTCGGTAATGAGCTATCCATGTCCAGCTTGGCCTCTATTTCGATGGAACCAGAGACCACAGTGCAAACGCTACAAAATATAGAAGATGAACTGCCGCCACCCTCAATCATTACTACAAATACATTACTAAACGCAAAGCGTATTAAGTGTAAAATCTGCACAAGTAACTTTCTGACACAAGACCAATTAAAAACTCACATGCTATCGCATAATGAAATACCGCATTTCTTTTGTGATCAATGCACGTTTTATACATTCTTTAAGATTGATTTAACGCAACATTACAAAACGAAACACAAACTGCAGCCCACACAGAAGCAGTTGCAACCGAAAAATAAAGTCAGACCGGCCGACAAGTCTGGcgattttaaacatatatacgCTTGCGATTTGTGTCTCTTTGAGACGCGTATAAAATCGCATTTGCGACGGCATTATTTGAGTCAGCATCAAGAAGAAGCGACCGAAGTGCAATTACGACCGACAATCGATGAATCAGCTGTTCTAACGGTACCAGAGATTTCACAGCCTGAATCATCAAAAAAAAGTGGCAAATCATTACGTCCCGACTATCCCAAAGGTTTGAATtgcaaaaagtgttcaaaaacattttattggCGCGAGAAGCTCAAAGATCACTATAGACAGCACGGTCTGGAAGAGAGCAATAACATAGATGCAACAGTTGGTGGCGGTTTGGATATCTCTGGGCCGGGCACAAGTTTACTAAAACACAACACATTTCAATATCATATGCCACAACATGATAGCAACAGCGTAAACAGCATGCTCAACACCAACCTCAGTCACAACAATTACAATAGCAATGTGGATGCGAGTGTGTTGGAGGCACAAGCAATTGTCGATGCAGCCGTAGCGGAGGCACAAGCCGCTTCAATGCAGATTAATTTGCAAATGAATCAACCAGCACCCGACATCATAATGGATATACCGGTAGCGACGACAATTTCCACCACCACAGTGCCAATGGATGCGACGGGCAATGCGAGCGATGTGCATGGCATGCAGCAGCAAGCAGTAAATGTGATGGGCGGCTATGCTTGTCCGCAAATACCTTCGGATGCCATACCGCAAGTGGTTGAGACGGACACAACCATCGATAACAGCGAATTGGATTTTGTTTTTAACGATGCGCTCTTCGAAGATTTCGAAGAAGATGAAAATGAGGACGAAGAGAATGAGGAGGATGACGGCGCAGACTTGCAAGATTTGCTGCTAACAAGTGATGACGATTTCGACGATATGCtgcaggaacaacaacaacagcaacaacttgaTGAGAGCGGTGTGGCTGCCGGTGACGCATCGACGAACAGCAGCACTTATCAGCCATATTGTGTGCACTGCAATAAGAAATACTTAAGTCAATATCAATTCGAAAATCACATGTTCGTGCATCGTGGTTTGGCTCCTTATCGCTGTGAAATGTGCACTAATTTGTACAACACAAAGCGTGCTCTGATTCGTCACTATCGCGCGGTGCATAAACGAATTCCAACGCGGGATATGATTCAGGCTAAGGGTGATAAAgttgTTGTCGATCATACGCCGATTGAACATTTGAATCTTATTGAACAGAAAGCGGTGACTTTAATGTGCGCGAAATGCCCTTACGAATCGGTGGATCTGCAAGTAATGCAAATGCATTTGAACACCATACACGGCCTTGCTGATGAGAACTACATCTTGCAAAAGTTGCCGTTCGAGTGTCCACGCTGCATACGTTCATATGCGACGAGAGCGCGTCTTATACGACATTTGGAACGCAGTCACTCGGTGGCGActataatacaacaacagcgTATGCCAAATAATACAATGCGaaatcaattacaacaacaacaatcatatataacaataaaagaCAGCGGCAATGCAACGtcaaaaacgacaacaacaacaacagttgcagCATTAACCACACCCTCCATAGCAgtgacaacaacatcaacaacgacAAATTCAAGTTGCGGCCGAGGCATTGAAACGCATTCATATcaatacaactacaacaacagcaacagcgaagGTGACGTTGATGCCAACGATTACGaggttggtgttggtgttgatgGTGGTGATAGCATTGaggacaataacaacaatgatgatgatgatgcacATGCTAGCAAAACatccaaagcaacaacaacagcaaccactaGAGCACATAAATCTAaatcaacaactacaactactagAGCCACAAAAAAATcgacaacaagaaaaacaaccaatacaacaacaattaccagTGCAATTACAAGTGACAACAAAAGCAGTACAACCGAAGCAGTTGAGCAAATACTTGCCTACGATAGCATGTATCATCAATTGAATGCAAGCAACGAGCTATTCGATGAATATGCCTGTGGCATGTGTTCGCAAAGTTGGCGCACAGCAGCCGAGCTGCATGCACACGAATGCATACGTGCGGCTGACAACAGCAACGTCGCCGCCGTTGCCGTGCGCACTGCGGGCGAGAGTGTAGGTCTCATCAATTCGGAACGTTCCCTTTATCTCTTCAAATGTGATATATGCCATTGCAATTACAAGTCCAGTGAATTACTCAAACATCACATGAAACGACATACGGCGCGTAAATTTCGTTGCAATCACTGTCCGAAGACGTACATCAATCGTAGCGAGTTGAAATTCCACCAACTCACGCATACCGGTGAGAAGCCGCACAAGTGTGAGATGTGCCCGAAACAGTTTCGCTATCCGCATCATTTGAAGCGTCATTGCGATGTCGTGCATTTGGGCAAGCGTGCACGCTGTCCGGTGGAGAGTTGCGGCCGCACATTTACGACGCAAGCGCAATTGAAGATACACTCGTGGATACATGACGGCAATGAACCGTACCGCTGCAAGTACTGTAGGGAATCGTTCAAGAAACGCGAGTCTTTACGGAAACATACGCGCCGCATACATAAATGCGATCTAACCGAGGAGGAAATCGCTGAAATCTATCGTCAAAGTGTTGGTCACACCAATCCGCATGACTTCACAGTGTCACTCTCGAATGGACGCATGCTGCGGCGTTCGGATCTTGAATTGGCCGCTCAACGTCCAGACGAATACACCAACGATTTGGCAGCCGAAACGGCAGCAGCCACAGCAGCAGCGGAGGTGGCGGCCGTTAGCATTGTACAAACGGAAATGGACGCTTCCAATGCACTCTCGCCGCTATTGGCATCCAATACACATGATAACATGAATTTGAAATTCGGCATGGGCGTCGAAGAGGAGGATGAGCATGCTGCGGTGTCTCATGTGTCACAGAGCAGCGCCTCATTGTCCACGCACGAGGAAAGCATACACACCTACATTCTACCCGGCATGGAAGAGCACGGGCAGTTGCCGCATTTCAAGCTTGAAAATTCCGGCACATTTTAG
Protein Sequence
MDADTALERTAPTDYRLVCRTCLASDAEFYKLDSPLFLEDDDSDQKPVSFMECLRYCTRLVDNDESENLEFPTYICTECSASLQVSYNFIKNALEAHEILRQKLSENSEQQQRKCKVQRKNGVIGENGCKSAGLEDGVDTEATKMRFRCKICNEKVETKKTLKEHIKLHLDIISYCCELCSFECKKRTLLFDHYKLAHNMQPTRDQLKPKTKQPVKKEHSDSEDPISQEMEKIHNTQINDEYMPNTQYAVTEQQEDLDMKLFLTPASSNASAAYVEAAAAATAIDVPTDTHEHRTSITKDLQQYGTDQFNITANELSVGNEFIVMADGTVEEVMGNGVVIEYINAADDGVTLENGLVLDNIMQVQPTGDADQAVTMDMDVDDIIIEEGVGNELSMSSLASISMEPETTVQTLQNIEDELPPPSIITTNTLLNAKRIKCKICTSNFLTQDQLKTHMLSHNEIPHFFCDQCTFYTFFKIDLTQHYKTKHKLQPTQKQLQPKNKVRPADKSGDFKHIYACDLCLFETRIKSHLRRHYLSQHQEEATEVQLRPTIDESAVLTVPEISQPESSKKSGKSLRPDYPKGLNCKKCSKTFYWREKLKDHYRQHGLEESNNIDATVGGGLDISGPGTSLLKHNTFQYHMPQHDSNSVNSMLNTNLSHNNYNSNVDASVLEAQAIVDAAVAEAQAASMQINLQMNQPAPDIIMDIPVATTISTTTVPMDATGNASDVHGMQQQAVNVMGGYACPQIPSDAIPQVVETDTTIDNSELDFVFNDALFEDFEEDENEDEENEEDDGADLQDLLLTSDDDFDDMLQEQQQQQQLDESGVAAGDASTNSSTYQPYCVHCNKKYLSQYQFENHMFVHRGLAPYRCEMCTNLYNTKRALIRHYRAVHKRIPTRDMIQAKGDKVVVDHTPIEHLNLIEQKAVTLMCAKCPYESVDLQVMQMHLNTIHGLADENYILQKLPFECPRCIRSYATRARLIRHLERSHSVATIIQQQRMPNNTMRNQLQQQQSYITIKDSGNATSKTTTTTTVAALTTPSIAVTTTSTTTNSSCGRGIETHSYQYNYNNSNSEGDVDANDYEVGVGVDGGDSIEDNNNNDDDDAHASKTSKATTTATTRAHKSKSTTTTTRATKKSTTRKTTNTTTITSAITSDNKSSTTEAVEQILAYDSMYHQLNASNELFDEYACGMCSQSWRTAAELHAHECIRAADNSNVAAVAVRTAGESVGLINSERSLYLFKCDICHCNYKSSELLKHHMKRHTARKFRCNHCPKTYINRSELKFHQLTHTGEKPHKCEMCPKQFRYPHHLKRHCDVVHLGKRARCPVESCGRTFTTQAQLKIHSWIHDGNEPYRCKYCRESFKKRESLRKHTRRIHKCDLTEEEIAEIYRQSVGHTNPHDFTVSLSNGRMLRRSDLELAAQRPDEYTNDLAAETAAATAAAEVAAVSIVQTEMDASNALSPLLASNTHDNMNLKFGMGVEEEDEHAAVSHVSQSSASLSTHEESIHTYILPGMEEHGQLPHFKLENSGTF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00193056;
90% Identity
iTF_01564067;
80% Identity
-