Basic Information

Gene Symbol
-
Assembly
GCA_028554725.2
Location
CM053022.1:51357373-51360239[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 8.6 1.1e+03 1.4 0.4 2 23 222 243 221 243 0.89
2 12 0.00034 0.045 15.3 0.2 3 23 288 309 287 309 0.94
3 12 1.5 2e+02 3.8 2.7 2 23 364 385 363 385 0.96
4 12 2.9e-06 0.00039 21.8 1.3 1 23 391 414 391 414 0.96
5 12 0.47 61 5.4 0.8 2 23 431 451 430 451 0.95
6 12 0.014 1.9 10.1 3.4 1 23 465 487 465 487 0.94
7 12 8.7e-06 0.0011 20.3 1.6 1 23 496 519 496 519 0.96
8 12 0.00013 0.017 16.6 1.2 1 23 524 546 524 546 0.96
9 12 3.3e-05 0.0043 18.5 3.3 2 23 552 573 551 573 0.97
10 12 0.0066 0.87 11.2 2.3 1 23 579 601 579 601 0.97
11 12 0.0008 0.11 14.1 3.2 1 23 606 628 606 628 0.95
12 12 0.079 10 7.8 1.4 1 23 633 657 633 657 0.97

Sequence Information

Coding Sequence
ATGGTAAACCAATGTCGCGCCTGCCTCAATTCGAAAGACACCGCCTTTATACGTATGGAGACGCACATAGCTGATGGCTTCGATTTTTTTACTTGCTTCAGTTTATGCACACAACTGGAAGCGGGGCTTGATGATGGCCTGCCAGGAGTATTATGCACACATTGCTCTCAGGATCTCGAAATCTCATTTAATTTCATGCAAAATGCCAGACAGGCTGATGGTATACTCCGAGAGAGCATGTCACAAAAGTACTTGTCCGATGAAATTGAAACATTGGAGACCGAAATTGGTAATACAATTATGGAGCCATTGGAAGTTGTAGAAGATAGTGAAGTTGAAGATTGTGTGGTGGAGGAACTTATAGAAGATGTACTTGTACCAGGAGACGTCGCCGAAAGCGGTGTGGTTGAAATAATGGAGGTTGAGAACGATGGGCTAAACATTTGTGAAAGTTCTCTGGATGAAATAGAACTTGTAGAAAACCATTATGTGGATCGAACTGTTGAGACCGCTGAGGTTGAGTTGGACGAAGAACATGAATCACAGCGAAAAACAGGAGAGTATTATGCAGAAGATGAGGGAGACGAAGTATACCTAAAAGAGTACAAAGAAAATGTTGAGCAATCGGATGCAGAAAATCCGAGCTCAAAAGGAGGAAAATGGAAATGTATAGAGTGCAAACGTGTCTTGTGTGGCGATGTCTCTTATGAAGGCCATATGAACATGCACCGCTCATTGCGACCATACAAATGTAcgctatgtatgtgtgcattccGTTGCAAAAATAAACTGGACCAACATATACAGCTGCGTCATGAACAACCACCAAATGACACGCAAAACGCGAATCctaGCAACAATTGTCagaaatgtacaaaaattttCGAGACACCCGAGGAATTACAAGAGCACCAAGAATTAATACATCCCGATAGTAATCCTGTACAATGTAGACGCTGTCCGCTACTAGCACCATTTGCGCGCACAAAACTAGTGGAACACTTTCGTAATGAACATCCAACGGaacatcgaaaatattttcccaCAGTGGGTAGGCCACCAAACGAACCAGCCAAACCAACACCATGGCAATGTGAAGTGTGTAAATGTTATATGCGATCAGAGGCAGCTTTGCGTGATCACCGGCACACTCACCAGCATGAACGGCCACATGAGTGCCAAATTTGTGCGAAACGTTTTGTTACTACAAGTAATTTACGCCAACATATGCGCGGCGTACACACCGAGGAATATGAGAAGTTGGTGAGTGAAGGCGGCGATACGATAGTGCAAtgtgaaatgtgtaaaaaacaacTACTTCGACGAAATCTCGATAAACATATGGCCTTACATATGAGAAAGGAGCGTGAGGCGAAGGAGACGCAAACGAAATTTCTTTGTGCCTATTGTTCACGCGAGTGTAAAAGTCAAAAATCCCTCAACCAACACGAGAAACTGCATCAGGGAGCCTCGCCTGATGTTATATACATTTGCAACGACTGTGATCGTTCCTATGCGACACAACACTTGTTGCAGCAACATCGTAAGCAAGCGCACAAAGAACGGGATCACTTCTGTCCGATATGTGGCAATGGTTTCAAGCTCAAGAATCAATTGGTGAATCATATGAAATTGCATTTggaaaagaatataaaatgtcCGCATTGTGAGAAATGTTATGCGCGTAAATTCGATCTGGATGTGCATTTGCGCAGTCACACGGGAGAGCTACCATTCGCGTGTCACCTGTGTGAGAAACGTTTTGCGATAAAGGTACGCCTGACCTACCATTTGCAGAAGCACTATGGCATAAAGCATCGTTGCAAGGATTGTGGTGCGGAATTCAATTCGAAACAGAAATTAAAAGCGCATAGTTTCAAACATACTGGCATGCCGTATAGGTGTGAGCGATGTGATGGACATGGCTTCGCCAATCGTGATGTcTTCAAACGACATTTGCAGCGTGTGCACTGCGCCAGTATGAGTGATGAAGAGTTGGTGGCCATGTTCCAGCAAAACACTGGCAAGGCCACACGCATACGGCAGGTTGAATATTTTGAGGATAATTCGCAAGAAGAGCCTACAAAGAACGCTGCGGAAACGGACAACACTTTGATTAACGCAGATGAGATTGCACTGGAATCGGAAGTGATACACAGCTGA
Protein Sequence
MVNQCRACLNSKDTAFIRMETHIADGFDFFTCFSLCTQLEAGLDDGLPGVLCTHCSQDLEISFNFMQNARQADGILRESMSQKYLSDEIETLETEIGNTIMEPLEVVEDSEVEDCVVEELIEDVLVPGDVAESGVVEIMEVENDGLNICESSLDEIELVENHYVDRTVETAEVELDEEHESQRKTGEYYAEDEGDEVYLKEYKENVEQSDAENPSSKGGKWKCIECKRVLCGDVSYEGHMNMHRSLRPYKCTLCMCAFRCKNKLDQHIQLRHEQPPNDTQNANPSNNCQKCTKIFETPEELQEHQELIHPDSNPVQCRRCPLLAPFARTKLVEHFRNEHPTEHRKYFPTVGRPPNEPAKPTPWQCEVCKCYMRSEAALRDHRHTHQHERPHECQICAKRFVTTSNLRQHMRGVHTEEYEKLVSEGGDTIVQCEMCKKQLLRRNLDKHMALHMRKEREAKETQTKFLCAYCSRECKSQKSLNQHEKLHQGASPDVIYICNDCDRSYATQHLLQQHRKQAHKERDHFCPICGNGFKLKNQLVNHMKLHLEKNIKCPHCEKCYARKFDLDVHLRSHTGELPFACHLCEKRFAIKVRLTYHLQKHYGIKHRCKDCGAEFNSKQKLKAHSFKHTGMPYRCERCDGHGFANRDVFKRHLQRVHCASMSDEELVAMFQQNTGKATRIRQVEYFEDNSQEEPTKNAAETDNTLINADEIALESEVIHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00190210;
90% Identity
iTF_01564077;
80% Identity
-