Basic Information

Insect: Zeugodacus cucurbitae
Gene Symbol: RREB1
Assembly: GCA_028554725.2
Location: CM053022.1:62724739-62731362[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.017 2.3 9.9 2.1 1 21 297 317 297 319 0.95

2 14 0.00036 0.048 15.2 0.1 1 23 329 351 329 351 0.98

3 14 2.8e-05 0.0037 18.7 7.5 1 23 357 379 357 379 0.98

4 14 0.51 67 5.3 2.3 2 19 657 674 657 674 0.96

5 14 0.064 8.5 8.1 0.0 2 21 690 709 689 710 0.93

6 14 0.01 1.3 10.6 0.1 1 23 878 900 878 900 0.97

7 14 2.3e-05 0.0031 18.9 1.2 1 23 910 932 910 932 0.99

8 14 0.00074 0.098 14.2 2.2 1 23 938 961 938 961 0.97

9 14 0.0036 0.47 12.1 2.0 1 23 1270 1293 1270 1293 0.95

10 14 0.0001 0.014 16.9 0.3 2 23 1653 1674 1652 1674 0.97

11 14 0.18 23 6.7 6.3 1 23 1680 1703 1680 1703 0.97

12 14 2.5 3.3e+02 3.1 5.1 1 23 1821 1844 1821 1844 0.97

13 14 0.01 1.3 10.6 0.5 3 23 1899 1919 1897 1919 0.96

14 14 0.0016 0.21 13.1 4.8 1 23 1925 1947 1925 1947 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.017	2.3	9.9	2.1	1	21	297	317	297	319	0.95
2	14	0.00036	0.048	15.2	0.1	1	23	329	351	329	351	0.98
3	14	2.8e-05	0.0037	18.7	7.5	1	23	357	379	357	379	0.98
4	14	0.51	67	5.3	2.3	2	19	657	674	657	674	0.96
5	14	0.064	8.5	8.1	0.0	2	21	690	709	689	710	0.93
6	14	0.01	1.3	10.6	0.1	1	23	878	900	878	900	0.97
7	14	2.3e-05	0.0031	18.9	1.2	1	23	910	932	910	932	0.99
8	14	0.00074	0.098	14.2	2.2	1	23	938	961	938	961	0.97
9	14	0.0036	0.47	12.1	2.0	1	23	1270	1293	1270	1293	0.95
10	14	0.0001	0.014	16.9	0.3	2	23	1653	1674	1652	1674	0.97
11	14	0.18	23	6.7	6.3	1	23	1680	1703	1680	1703	0.97
12	14	2.5	3.3e+02	3.1	5.1	1	23	1821	1844	1821	1844	0.97
13	14	0.01	1.3	10.6	0.5	3	23	1899	1919	1897	1919	0.96
14	14	0.0016	0.21	13.1	4.8	1	23	1925	1947	1925	1947	0.99

Sequence Information

Coding Sequence: ATGCTCGCCACAGCAGCCGCTAGCACACAATCCGCACTGGATGCCATACAAACGAACGTCACAAAGATGGAACGACGTGATTCGACAACATCGGAATCATCGTTGGAACACTTGGATTTGGGACGTACACCGAAGAAGCTAAGCTCACACTCATCGGCCACATCGACGCCGCATACAAACACCAAcagcaccagcaacaacacaaacaacaacaacagaattaACAGCAATGATGTGCTTACAAAAGTTGCCACCACCGCTGTGAGTGGTGCCACCACAACATTACTGCCACATCACCAGCACGGCCACATCAACGACTCCGATGAGGCGAATGATTATGACGATGACGATGAGGAGTCGCCAGATGACGAACAGTGCGGCAACAAACTGAATGCACTCAATTCGCGATCACAGCGTCATCACAAGCGTCGCAGCACAGCGCCACGTCTAGACAAACGCACCAGCGTACATTTGGAATTCAATGCGGACGATCCGAATTCGCTGCGCAAGAAGTTCCGTTTCAATCGCAGCCACTCGGCCTCCGAACAAATGTCCAATAATAATGAGTCTGGTTTTGTGGACGCCAGCTGTAGTAGTCATTACCTAAATGCGTCGGCTGTGTCtttggcggcagcagcagcagtggctgCAGCGGCGGCAACGACGACGACACCATCAACCACAGCAAAGGCAATTAGCATGACGCCGGCACTGCATAACTCATCGGCGTCGGTATCAGGCTCGGGTTCGGTCTCGGCGACAGGTTCGCACAGTTCGTCGTCGGCTGCGTCCTCGCCGCGTGGCTGCGGTGCCGGTTTGGCTGCTTCCTCCGCCTCGGTATCCAGTCCCGAATCGGGTATTTGCGATAGAGATCGTGAGGACATGAAGTTCGTATGTACTATCTGCGATGTGGTGTCGGCGACCCGTCACGAATTCACGAATCATATACGCTGTCACAATTACGCCTCCGGAGATACGGAGAACTACACATGTGCTATTTGCTCCAAGGTGCTCTCCTCGGCCTCCTCACTTGATCGGCATGTGTTGGTGCACACAGGCGAACGACCATTCAATTGCAAATATTGTCACCTCACCTTCACCACCAACGGCAACATGCATCGGCAcatgcgcacacacaaacaGCATCAGCACAATCATCATCATCGCCGCAACTCGAATGGAACCAAACAAAGCAGTcatagtcacaacaacaacaacaatacagcaAGTATGCTCACAAGCAGTGGCGGAACCGACGCTTTCGCCTCAGCCACCAACACTTATGCGCAATTAAGTAATGGCTTGTTGATTGGTGAAGGTGGTGTCAAAACATCAACAGCATCTGCCGAGGCATTAGCCACTGCTGCCACCACTGTGCCAACAGCCAACGGTGTAGGTGTTAATGGTAAACGCTTACACAGTAGCGGCGTAGAAAGTTGCGAAAGTGATGGCGGTTGCTCAACAGACTCCTCATCAAGTGCCATCAGCCATAGCTCAAATAATAAtcaacgcaacaacaaaaacaatgacaacgacaatatcaacaacaatgccacaaataattacaacaacaatatgaacgCGAAGCGTAATCGTTTAGGTAATTTTAAGCGAAAGAGCAGTGAACAACATGACGAAGCGGATGGCGACGCCGACGAGCTGGCAGCGGCGAAGCGACGCATGAAGACCACcataaacaacaatataatcGGCGAGGATGTGGATGAAGTTGATGCGCGCATCGGCGGTCACAATAATGACGCTGGCGCAATGGTAACGACAAAAACCAGCGCATCCTCTTCCGCATCGGTCATGTCGGCGGATGACCACGATGTTGACGATGATGAGGACGTCGAGCAGAAGCCATACTTCGCCTGCCCCGTCTGTCCGGTCTGCAATGCGGGCGACTTTGCCGACACACACGCGCTGGACAATCATTTGGACAGCGAGCACGCCGATATACCCGCGAAGTGCCGTCATTGCGAGGTCGTCTTTCGTACACACCGCCAGCTGAGCTTGCATCCGTGCACGCAGCGCTTGCTCGGCAGTCGTCAAATGCCGTTGGTGGAGTGTGTGAAGTGTGGTCAGAGCTTTGAAAATGGCGACGCTTTGGAGCTGCATGCACGCGACTGCGATACCAACGAGCTGCGCCATGCGCGGCGTAGTCGCAGTCTAAGCGACAGTTTTGCACCGGCGCATTTGACGGAAGCCGAAATTGAGGATAAAACCAACCAAATACGCAATAACTTCTTGCGTCAGTTGTATCTGCAGAGTCAGAAGCCACTCTGCGCGCAGAGTTTGATGTCGCTACCCTCGCCGCAGCATTCCACACACGATGAAGTGGATTCGCTGAACGTGAGCAATACCGATATCAAAGTCGAGGCAGCAGACGCAGAGCCAGCAGATCAATTAACAAGTAATTTGCTGTCACAACAGTCACATGACTCGAAAGATCTTGCAGACATACAGTCGATACTCAATATGACTTCGTCGTCATCAACATCAAATTTTCTGAAGAACTTCGAACAATCGGTGAACACACCATCCAGCAATTATAGTTTGGATAAAGACGAGGAGGAGGCGCAAGATGCCTTCACATCCGAGTTTCGTAAAATGAAATTGCGCGGTGAGTTTCCTTGCAAGCTCTGCACAGCGGTCTTTCCGAACTTGCGTGCACTCAAAGGACACAATCGTGTGCATTTGAGCGCAGTTGGACCAGCTGGTCCATTCCGTTGCAACATGTGCCCTTATTCCATATGCGATAAGGCTGCGCTGGTGCGTCACATGCGTACACACAATGGCGATCGGCCCTATGAATGTGCCGAGTGCAATTATGCCTTCACCACGAAGGCCAATTGTGAACGCCATTTACGTAATAGACATGCGAAGACTACACGCGACGAGGTCAAACGTGCCATCATATATCATCCATCCGAGGACTCAACTTGCGATGATCCCGCGAAGAAGCTGCATATGTTCTCATCGCCCGATTTCGATGACGATATGGAGTTGCAGTATCAGCAGCATCATCCCAAAGATCGTTCAACTCCCGTGTCACATCTTAAAGAAATCTTAACCGCCGAAAGTCCTGCTGCCAAACCCTTAAAGATACAAGTTAAGAGTTTAGAGCAATTGTTGGACAAATCAACCGGTTCGGTTGGTAGCTACAATGACTCCTTCGAAGAACGCACAGCAGCGTCGTCCAACGAGACAGCACCTATCGATTTGAGCATGGATGTTTTGGATCTTAGCAAGAAACCTACAGCTAAGCCAGTCGAGAAGGAGACGATTACTGCGTCTGCGCCGCAAGTAACGGAAAATGTTATTGATCCGGAGAAGAAGCTTGATTTATTCTCTTACGTGAAGGAGAATTTAAATATGCCAAAAATGCTGGAACTCTGGAGTTTGTCCACGCAACTCCCGTTCATGCCCGACTTTGGACCACTTATGAGCCAAATGTTTGGCGGCAACCCTGCTGCTATTCCATTTCTACCACCTGGTTTGGACTTGAATAAAGCAGGTATGCAAGCACCGCCAAACATGACACCACCAATGTTACCGAATTTGAACTCGCTCATGGCAGACAAGCTAAACACACATCCCCATAGCACACCAGATGTCAATCTGATGAATCAAATGTTGCCCACGTCAATGATGACGCCACCTCCACCGAATAGCGGCATGAATATGGCGCGTCATTCGCACATTCCACCAACGGTATTGCCAGGTGGCCCAGTCAAGATGGTGATCAAGAACGGCGTACTCATGCCGAAGCAGAAGCAGCGTCGTTACCGCACCGAACGCCCCTTCGCCTGCGAGCATTGCTCCGCACGCTTTACACTCCGCTCAAATATGGAGCGTCATGTCAAGCAACAACACCCACAGTACTACGCACAACGTCACCGCACCGGTCACCACAGCATGCGCGGACGCGGCGCCAGCAGCGCAACGGCCATGAACAGCATCTCACATTTGCAGGCGGCAATTGCGCAAGCGCACACCGCCAATCAGGTACAAGGGAATGGTCTCGGTGCTTCACCCATATCGGAGCAGGTTAAGTATGCTATATTGGCGCAGCAGCTGAAGGCACACAAGGACACCGACTTGCTGCAACAAGCGCTAGCGCACGGCTCAAGTAGCATCGCCAATAGCCATCATATGTTGTTGAATGCTGCCGGCGCTGCACTCGGACCACTGGGCCCTCCTAATGCGCTCCAGTTTCCATTCAGTCAATTGGGTCAGTCCACGAACATTAACGGCACCGCTGAAGATGATGAGCCCAAATTGATTATTGACGAGGATGACGAAGATGATGATGTCGAGGAGATACTTGACGACAATGAAGAAGACGAAGAGTTGCAGTTGTCAAATGAACACTACGACAATATGCGCAAATTTCAAACGCCAGCACCCGTTGTGGAGGAAGTGAAGACTGCACCTTCAACCGCCAGTGAGTCGAACAATGAGACCGCCAAAAAGGTTGCCGAAACCATACTGGAACAGGCGAAGAAAACTGGTCAGAAGCCAAATCAAACCACTAGCAAGTCCAACCCCAACTTTGCCGCCAAGCCCACAACAACTAAAACCGTTGCAACAGCTACCACACCGGCAGCTCCAGCGGCGCCTGTCACGCCAGCCAACACAATGAAAGCCATGATCGCACGAGCCGAGTCCGTGGGCAAGTTTCTGAAAGAGGTGGCCAGTTCACCCTTCAAAGATGAATCGCAAGATCTGGTGCCGGTTGCCAAACTGGTAGACAATGCTACCAGCAATGCCGTttcattcaacaattatttccgTCCCAGCGATGTAGCCAATCATATGGAACAAAGTGACGAAGAGGGACTGGTGGCCTCCGGCAGCGCCAGTGAAAGTAATCACTCTGGCACCGAAGACGTCGCTGCACCGGCCGAGCCGAAAAAGAAATCAGCCTATAGTCTGGCGCCAAACCGTGTCTCATGCCCCTACTGCCAACGCATGTTCCCCTGGTCCAGCTCGCTGCGACGCCACATACTAACGCACACCGGCCAAAAACCCTTCAAGTGTTCGCACTGTCCACTGCTCTTCACCACAAAAAGCAATTGTGATCGACATTTGTTGCGCAAGCATGGCGACGTTGAGTCCGCGGTGTCGGTCTATGTGCCAACCGAAGATGTCAGCGAGCCGATACCGGTGCCAAAATCAGTGGAGGAGatcgaacaacagcaacggcaACGCGAAGAAGAGGAGCGCAAACGCAAAGCTGAAGAGGCGAAATTGGAGCGTGAACGCCGTGAGAAGGAGCAGCGCTTACAGCAGGAGAAGgaacaacaaaataaactcTTAAAACAATTGGCTGTCgcacaactgcaacaacagctCAATGTCTCAATGAGCGCCGCCGCCGCAAACGCGAACAGCAGCGCCGAGGCTGATGCACGCGCCAAAGAGAATCTCTCACAGCTCAACGCCGATTTGCCATACAAGTGTCATTTATGTGAAAACTCTTTCGCCGAGCGCTTCAACTGCCTGGAGCACATCAAGAAGCAACATGCGCCCGAATTCACCTTACTGCTAAGCAAGGGTGCCATCGTCAGCGATGCCGAAGCCAACCAGACACAACTGCTCGAAGAGGAGGAACGACGTGTGGGCGAAGAAGCGAATAACTTTGCGCTACTGCCAAAACTACCGGCCTACACAAACAGAAAAGTGATTTGCGCCTTCTGCGTGCGTCGCTTCTGGTCCACCGAAGACTTGCGCCGACACATGCGCACACATTCTGGTGAGCGGCCCTTTCAGTGCGAGATCTGCCTGCGCAAATTCACGCTGAAGCACAGCATGTTGCGACACATGAAGAAGCACACAAGTCGCGGACAAAATGGCGTCGGCGGTGGTGATGGCACCTGCGCATTGGGTAACAGTGGCTCGGACTTCTCGGATGACGAACAAATGCCAACACCAACTTCCACTTCGACGGATACCTCATCCAACGCGACTACagcaactacgacaacttcggCGCCCACAGCGACAGCTGCCGCGCAGCGTACCAACAAAATACAGGAGCTGCTGAGCAAAACCAACGAATGGCGCAGCTCAAACTTGGCTGGCGAACAAAAGGAGAATATCGGCGAAGAACAACCGAATGGGCTGCACAGCGATTTGATTGGGAATCTGTTGGGCATCAGCGATCAAGGTATACTCAATAAATTACTCTCATCTCCCGATGAAGCGGCCAAACTGTTGGGTGTGGAGAAGTAA
Protein Sequence: MLATAAASTQSALDAIQTNVTKMERRDSTTSESSLEHLDLGRTPKKLSSHSSATSTPHTNTNSTSNNTNNNNRINSNDVLTKVATTAVSGATTTLLPHHQHGHINDSDEANDYDDDDEESPDDEQCGNKLNALNSRSQRHHKRRSTAPRLDKRTSVHLEFNADDPNSLRKKFRFNRSHSASEQMSNNNESGFVDASCSSHYLNASAVSLAAAAAVAAAAATTTTPSTTAKAISMTPALHNSSASVSGSGSVSATGSHSSSSAASSPRGCGAGLAASSASVSSPESGICDRDREDMKFVCTICDVVSATRHEFTNHIRCHNYASGDTENYTCAICSKVLSSASSLDRHVLVHTGERPFNCKYCHLTFTTNGNMHRHMRTHKQHQHNHHHRRNSNGTKQSSHSHNNNNNTASMLTSSGGTDAFASATNTYAQLSNGLLIGEGGVKTSTASAEALATAATTVPTANGVGVNGKRLHSSGVESCESDGGCSTDSSSSAISHSSNNNQRNNKNNDNDNINNNATNNYNNNMNAKRNRLGNFKRKSSEQHDEADGDADELAAAKRRMKTTINNNIIGEDVDEVDARIGGHNNDAGAMVTTKTSASSSASVMSADDHDVDDDEDVEQKPYFACPVCPVCNAGDFADTHALDNHLDSEHADIPAKCRHCEVVFRTHRQLSLHPCTQRLLGSRQMPLVECVKCGQSFENGDALELHARDCDTNELRHARRSRSLSDSFAPAHLTEAEIEDKTNQIRNNFLRQLYLQSQKPLCAQSLMSLPSPQHSTHDEVDSLNVSNTDIKVEAADAEPADQLTSNLLSQQSHDSKDLADIQSILNMTSSSSTSNFLKNFEQSVNTPSSNYSLDKDEEEAQDAFTSEFRKMKLRGEFPCKLCTAVFPNLRALKGHNRVHLSAVGPAGPFRCNMCPYSICDKAALVRHMRTHNGDRPYECAECNYAFTTKANCERHLRNRHAKTTRDEVKRAIIYHPSEDSTCDDPAKKLHMFSSPDFDDDMELQYQQHHPKDRSTPVSHLKEILTAESPAAKPLKIQVKSLEQLLDKSTGSVGSYNDSFEERTAASSNETAPIDLSMDVLDLSKKPTAKPVEKETITASAPQVTENVIDPEKKLDLFSYVKENLNMPKMLELWSLSTQLPFMPDFGPLMSQMFGGNPAAIPFLPPGLDLNKAGMQAPPNMTPPMLPNLNSLMADKLNTHPHSTPDVNLMNQMLPTSMMTPPPPNSGMNMARHSHIPPTVLPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQYYAQRHRTGHHSMRGRGASSATAMNSISHLQAAIAQAHTANQVQGNGLGASPISEQVKYAILAQQLKAHKDTDLLQQALAHGSSSIANSHHMLLNAAGAALGPLGPPNALQFPFSQLGQSTNINGTAEDDEPKLIIDEDDEDDDVEEILDDNEEDEELQLSNEHYDNMRKFQTPAPVVEEVKTAPSTASESNNETAKKVAETILEQAKKTGQKPNQTTSKSNPNFAAKPTTTKTVATATTPAAPAAPVTPANTMKAMIARAESVGKFLKEVASSPFKDESQDLVPVAKLVDNATSNAVSFNNYFRPSDVANHMEQSDEEGLVASGSASESNHSGTEDVAAPAEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGDVESAVSVYVPTEDVSEPIPVPKSVEEIEQQQRQREEEERKRKAEEAKLERERREKEQRLQQEKEQQNKLLKQLAVAQLQQQLNVSMSAAAANANSSAEADARAKENLSQLNADLPYKCHLCENSFAERFNCLEHIKKQHAPEFTLLLSKGAIVSDAEANQTQLLEEEERRVGEEANNFALLPKLPAYTNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHTSRGQNGVGGGDGTCALGNSGSDFSDDEQMPTPTSTSTDTSSNATTATTTTSAPTATAAAQRTNKIQELLSKTNEWRSSNLAGEQKENIGEEQPNGLHSDLIGNLLGISDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00191533;
90% Identity: iTF_01563987;
80% Identity: -