Basic Information

Gene Symbol
-
Assembly
GCA_028554725.2
Location
CM053022.1:51349799-51352895[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.37 49 5.7 3.2 1 23 175 198 175 198 0.90
2 16 0.099 13 7.5 0.0 3 23 204 225 202 225 0.90
3 16 0.011 1.4 10.6 0.8 1 23 231 253 231 253 0.97
4 16 0.011 1.4 10.6 0.0 1 23 276 298 276 298 0.97
5 16 0.002 0.26 12.8 0.9 1 23 300 323 300 323 0.97
6 16 0.0011 0.15 13.6 1.5 1 23 539 562 539 562 0.97
7 16 1.6 2.1e+02 3.7 0.6 2 23 572 593 571 593 0.89
8 16 0.0045 0.6 11.7 0.6 2 23 600 621 600 621 0.95
9 16 1.1e-05 0.0015 19.9 0.3 2 23 628 649 627 649 0.97
10 16 0.0039 0.52 11.9 2.3 1 23 744 767 744 767 0.97
11 16 1.6 2.1e+02 3.7 0.6 2 23 777 798 776 798 0.89
12 16 0.0065 0.86 11.2 0.3 2 23 805 826 805 826 0.95
13 16 1.6e-05 0.0022 19.4 0.2 2 23 833 854 832 854 0.97
14 16 0.004 0.52 11.9 3.9 1 23 860 882 860 882 0.97
15 16 5e-05 0.0066 17.9 1.5 2 23 888 909 887 909 0.92
16 16 1.9 2.5e+02 3.5 0.5 1 10 915 924 915 928 0.83

Sequence Information

Coding Sequence
atgcacTGTCGTGCCTGTATGCAAGTAGATTGTGAGAAGGCTGTGGATATGAATTATGCCACATCTGGAGATGATGGTAAAACTTTATACGATTACTTCAATGAGTGCACGCAACTACAAGCTACATCGCACGATGAACTTCCACAAATATTATGCAGTACCTGCATAGAAGATCTATATGATGcctataattttataaacaggGCTCGTACATCAGATGGAGAACTTAAAAAGTTGCTGACATTACAAAAAGCCGACACAGACATATATACTACTACTCAAACTACACAGTATGTAGTGGAATGCATAAATGATCCCTTAGCGACACCGGAACGAGAAATTGCCGTAACTGAAACTTTCATTACTGCAGAGGGCGCTGAAGTGGCTATACCCGCCTCTGAAATAAAAATAGAGCTGGAGCTGCCTGAAGATTTTGAAAACACAGTTGAGGATCATGCTGTCAAAAGTTACTCCGATTCTTCACTACAGGGTAACAGTGACGTTGTCATGCCTGTAGTAACTCATTCTTGTGAACTATGCGATTGTTCATATTTAACGCAAAAGGAACTGAAAGATCATATATTTGATATGCACAAGTCTGATATAATCTGCATGAAATGTCCGAAAGTATATGAGCTTCCTACGGAACTACGGCTACATGAATCACTTGTACATAGCACGGAAACATCATTTCAATGTGTATGGTGTAAGGAATCTTTTCAACGTGAAGAACTACCTAAACATATACGGAAGAAGCATAGAcattcttatttaaaatattttccgcgCATAAGAATCCATTGTAATAATGACAAGACGAATAGTTTTCGTTGTGATGACTGTCAAATAGCCTTTCCATCCATACTAGAATTAGCCTCCCATGTAAAGGATCATAAATTTGAATGTCCATTATGTCTGATGAGCTTTACAAAATATGGTTCGTATCGGGTGCATGTTAAACGCACACATAACCATTCCATAAGTAGTTTAAAAGCTGCGGTAGAAACTTTGCTTGTAGAACCTTTGATGGAATTTCCAAATGGAACTATTTCTGTAGAAAAATCATGTAAATCTCCAAATCGATCGTTTGAGGAAGCGCAAATGGAAATTGTAAAGGAGGTCGTACCAGTGACCATCACAGAACCACAAGATACCTCATTGCAGACCAAAGATAAACACACAAATGTAGTCACGACAAATGACTCTGTAAATAATTGTACAGGAAGCTTATTTAGATCGTTAGTTGTCGATGAAGGTGAAGATAAACCAATTGAATGTAAACCTCGCAACAAAAGCTATACAAGATTATGCTCAAACAATTATCACAAAATAACTGAATCAACCGATATAAATGATATGGAAGAAACTACTGATAATGAAATTGTGGATATTCTGGATATTGAAGCATATAAAGCGTCGATAGCTAAAACAGAATCGGAACGGAGCTTCTCACTTGCAGATTTAGCGTGGgaagctgaatccaaaaaagttgaatccgatgaaaatattttaggaaGTGAAGAAAATAATCTTGTTGATCAAGTGCCAAAGGAATCGgttcaaaagcaacaacaaaaacagaaaactaTTCCACAGTCAAAGGGAAAAAAGGGGTATTTTTGTTCATTTTGCCCACGTGTGTTAACTTCCAATAGGTCGTTGCAAACACACGAAAAAACTCAGCATCTCGGTAGAAAAAAAGATATTATGAAAGAGTGTCCCATCTgtcagaaaaaaatgtatatggaCTACATTAagaaacatattagaaatgtaCACGTAGGGGAACGTAATAACGTTTGCGATATATGTGGCGGCAGATACAAAACATTTAATACACTCCAACGGCACAAACTGTTGCATATGGCAGATCGCCAATGGCAATGCAGTGCATGTGATATGAAATTTGTGGACAAATATGCACTCAATAGACATATGCGCCTTCATACAGGCGAAATGCCATTAAATGATATGGAAGAAACTACGGATAATGAAATTGTGGATATTCTGGATATTGAAGCATATAAAGCGTCGATAGTTAAAAAAGATTCGGAGGAGATCCCCTCACTTGCAGATGTAACGTGGgaagctgaatccaaaaaagttgaatccgatgaaaatattttaggaaGTGAAGAAAATAATCTTGTTGATCAAGTGCCAAAGGAATCggttaaaaagcaacaacaaacaaagaaaaccaTTCCACATTCAAAGGGAAAAAAGGGGTATTTCTGTTCGTTTTGCTCACGTGTGTTAACTTCCAATAGGTCGTTGCAAACACACGAAAAAACTCAGCATCTCGGTAGAAAAAAAGATATTATGAAAGAGTGTCCCATCTgtcagaaaaaaatgtatatggaCTACATTAagaaacatattagaaatgtaCACATAGGGGAACGTAATAACGTTTGCGATATATGTGGCGGCAGATACAAGACAATTAATACACTCCAACGGCACAAACTGTTGCATATGGCAGATCGCAAATGGCAATGTAGTGCATGTGATAAGAAATTTGCTGAAAAATCTGCACTCAATATACATATGCGCCTTCACACAGGCGAAAAGCCATTTGCTTGTCATCTATGTGACCGACGATTTCGCATAGGGAGTCATCTTACCTATCATTTAGAGAGACatgataatataaagaaaaagtgCAACGTTTGTGGCAAAGAATTCACCAGCGCTACATCATTGCGAAAACACTCATTCCTGCATACTGGCGATATGCCGTATAAATGCACTGATTGCGACTATGAAACGGCTAAACGTGAATAG
Protein Sequence
MHCRACMQVDCEKAVDMNYATSGDDGKTLYDYFNECTQLQATSHDELPQILCSTCIEDLYDAYNFINRARTSDGELKKLLTLQKADTDIYTTTQTTQYVVECINDPLATPEREIAVTETFITAEGAEVAIPASEIKIELELPEDFENTVEDHAVKSYSDSSLQGNSDVVMPVVTHSCELCDCSYLTQKELKDHIFDMHKSDIICMKCPKVYELPTELRLHESLVHSTETSFQCVWCKESFQREELPKHIRKKHRHSYLKYFPRIRIHCNNDKTNSFRCDDCQIAFPSILELASHVKDHKFECPLCLMSFTKYGSYRVHVKRTHNHSISSLKAAVETLLVEPLMEFPNGTISVEKSCKSPNRSFEEAQMEIVKEVVPVTITEPQDTSLQTKDKHTNVVTTNDSVNNCTGSLFRSLVVDEGEDKPIECKPRNKSYTRLCSNNYHKITESTDINDMEETTDNEIVDILDIEAYKASIAKTESERSFSLADLAWEAESKKVESDENILGSEENNLVDQVPKESVQKQQQKQKTIPQSKGKKGYFCSFCPRVLTSNRSLQTHEKTQHLGRKKDIMKECPICQKKMYMDYIKKHIRNVHVGERNNVCDICGGRYKTFNTLQRHKLLHMADRQWQCSACDMKFVDKYALNRHMRLHTGEMPLNDMEETTDNEIVDILDIEAYKASIVKKDSEEIPSLADVTWEAESKKVESDENILGSEENNLVDQVPKESVKKQQQTKKTIPHSKGKKGYFCSFCSRVLTSNRSLQTHEKTQHLGRKKDIMKECPICQKKMYMDYIKKHIRNVHIGERNNVCDICGGRYKTINTLQRHKLLHMADRKWQCSACDKKFAEKSALNIHMRLHTGEKPFACHLCDRRFRIGSHLTYHLERHDNIKKKCNVCGKEFTSATSLRKHSFLHTGDMPYKCTDCDYETAKRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01563977;
90% Identity
iTF_01563977;
80% Identity
-