Zvit005385.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Zaprionus vittiger
Gene Symbol
gcl
Assembly
GCA_018904025.1
Location
JAEIFQ010000344.1:10888918-10891703[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 3.3e-20 9.1e-18 64.3 0.1 1 107 58 165 58 168 0.91

Sequence Information

Coding Sequence
ATGGGTCAAATTGTTGGATCCATGCAAACGAATGTGTCAGAAGTGTTTGGCAGTCGGCGGAAGCGACGACGCAGCACGGATTCCACGTTGTCACAGGAGGAGCGTGAACGAGGCGAACTGGACAGTAAATCACCCAAAAAAAAGAAACTCTTGACGACCACTCAATATATTTACAATGCCCTGTTCAAGGAGGAGAAGAACTCGGACGTGGGTGTTATGGCACTGGACAAGGTGTGGCATTTGCATAAGGTCTACCTGAGTCAGAGTCCCTATTTCTACACGATGTTCAATGGATCGTGGAAGGAGGCACAACAGAGTTTCGTACACATTAAGATACTGGACGATCGTATCACTGTGGAGAGCCTGGACGCAGTATTCGGTTCCATGTACTCGGACGAGATTGAAATCGATGCCAAAGATGTGATACCAGTGCTGGCAACAGCGACACTCTTCCACTTGGACGGCATCATTGACAAGTGTGCCGAGGTGATGGTGGACACAATAAATGCCGAGACTGCCATACAGTACTATGAGGCTGCCTGCCAGTACGGTGTGCTGAGCGTCAAGAAGTCAACGTTCCAGTGGTTCCAAATCAATTTACTTAGCATTTACAATAAGCATCCCAATCTCTTGCGGCACATCTCGATTGAACTGATGACCGCCCTCACTGCCAGTCACAATTTGTATGTTATGCAAACGGAATTCTCATTGTACACACTGCTGCGAACATGGATGTTTCTGCAGCTGCATCCCAACTATGATCCCGAGGATCCGGTGCAACGTGCCGAGGCACAAAAGACACAAGAACGTCTATCAAATGCGGGTGTTGAGACTCACACGCCCAGTGGGGATGTGGTGCAGTGGACGTACTTTGCCAGTCGCATGGAGGAGCGCTCCTTCCTGGCCACGCCCGAGGGACAGCCATATGTGTGTGTCTTCCAGAAGCTGCGCACTCAGTACCTGACCAATCATTATATGGATCTAAAGATCATATTCAATGACAACATCATACCCAAGGAATGGCTCTACAAGCACATACACAGCCACTGGGACGCGCTGCTCAAGATCGATCACGGTCAGGATGATGGCAGCCCCAAACAGTTGGACGATGAACAGTTCTTTGAGAACTGCATGCGCTGTGGCCGCCTGCTGATGGAGCCCGGCTATCAGAAGTGGCGCTGGACGGGCTTCAATTATGGCATGGATCTCATACTCATTATGGACTCGCGTCGACTGAACATACGCCGACATCATCGGCACGAGCACGAGCGTGTGTTGAGCCTGCAGACGAGGCGTAAATTCATGATACGCACCACAGTTACCTCGATCAATGCCCAGCGACAGCCGATCTTCACACAGAAGTCGGAGATCACAACGTTGAGTCTGGAGAAGAACGAGGAGGTCTCACTGATGGTGCTCGACCCGAAGCTAGTGCATCCGTTGCTCATCTCCATCAATATGCTTGTTGTGATGCCGCCCAGCCAGAGCTTCAAGGAGATTGTGCCGCAATGTGAAGAGCCAGGATTGTCTGCAGCTGCTATACCCATTTCAGAGATAGGCGCCAGCTGTGAGCGACCCTTGACCCCAGCTAGTGCCGATGATTCGGCTGTGTGTGTGAGCAGCGGCGATGGTTTATCAGGGGCGTCGACGCCCTCTTCCCCGTCTCTGGGTCTGCGACCATCAGCACGTTTTAGTACCCAATACGTATCAAATCTCACGTCTCCAATCCTGTTTTACAATTAA
Protein Sequence
MGQIVGSMQTNVSEVFGSRRKRRRSTDSTLSQEERERGELDSKSPKKKKLLTTTQYIYNALFKEEKNSDVGVMALDKVWHLHKVYLSQSPYFYTMFNGSWKEAQQSFVHIKILDDRITVESLDAVFGSMYSDEIEIDAKDVIPVLATATLFHLDGIIDKCAEVMVDTINAETAIQYYEAACQYGVLSVKKSTFQWFQINLLSIYNKHPNLLRHISIELMTALTASHNLYVMQTEFSLYTLLRTWMFLQLHPNYDPEDPVQRAEAQKTQERLSNAGVETHTPSGDVVQWTYFASRMEERSFLATPEGQPYVCVFQKLRTQYLTNHYMDLKIIFNDNIIPKEWLYKHIHSHWDALLKIDHGQDDGSPKQLDDEQFFENCMRCGRLLMEPGYQKWRWTGFNYGMDLILIMDSRRLNIRRHHRHEHERVLSLQTRRKFMIRTTVTSINAQRQPIFTQKSEITTLSLEKNEEVSLMVLDPKLVHPLLISINMLVVMPPSQSFKEIVPQCEEPGLSAAAIPISEIGASCERPLTPASADDSAVCVSSGDGLSGASTPSSPSLGLRPSARFSTQYVSNLTSPILFYN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01356230; iTF_00514985; iTF_00474597; iTF_00611441; iTF_00564018; iTF_00580842; iTF_00473892; iTF_00574923; iTF_00471727; iTF_00484529; iTF_00536146; iTF_00480952; iTF_00517816; iTF_00487390; iTF_00603450; iTF_00601150; iTF_00485248; iTF_00492331; iTF_00613591; iTF_00505504; iTF_00600416; iTF_00483797; iTF_00501149; iTF_00577886; iTF_00591070; iTF_01319148; iTF_00339277; iTF_00832274; iTF_00901603; iTF_00520019; iTF_00502625; iTF_01549665; iTF_01556929; iTF_00545346; iTF_00585314; iTF_00546755; iTF_00608547; iTF_00610755; iTF_01323491; iTF_00506980; iTF_00558020; iTF_01322756; iTF_00551685; iTF_01327269; iTF_01552549; iTF_00559590; iTF_00584519; iTF_00583784; iTF_00599688; iTF_01325768; iTF_00506217; iTF_00550985; iTF_00617002; iTF_00478827; iTF_00563275; iTF_00587499; iTF_00528908; iTF_00537612; iTF_00573420; iTF_00473165; iTF_00531053; iTF_01554061; iTF_00516366; iTF_00575694; iTF_01322030; iTF_00561135; iTF_00582351; iTF_01321296; iTF_00523057; iTF_00554481; iTF_00598257; iTF_00549650; iTF_00567634; iTF_00586066; iTF_01551826; iTF_01554802; iTF_00544595; iTF_00569075; iTF_01324243; iTF_00475316; iTF_00540468; iTF_00579380; iTF_00806068; iTF_00476725; iTF_00512821; iTF_00538325; iTF_01553333; iTF_00493751; iTF_00510647; iTF_00495960; iTF_00526680; iTF_00586776; iTF_00534681; iTF_01320569; iTF_01326521; iTF_00479578; iTF_00508442; iTF_01557658; iTF_00533915; iTF_00572699; iTF_00601915; iTF_00470972; iTF_01327997; iTF_01556221; iTF_00532478; iTF_00547454; iTF_00519263; iTF_01325023; iTF_01570335; iTF_00490880; iTF_00568352; iTF_01559136; iTF_00336065; iTF_00596034; iTF_00521505; iTF_00528161; iTF_00548929; iTF_00499683; iTF_00593219; iTF_00514276; iTF_00485957; iTF_00577158; iTF_00616295; iTF_00497512; iTF_00498250; iTF_00543850; iTF_00558827; iTF_00522316; iTF_00542540; iTF_00518541; iTF_00560397; iTF_00553134; iTF_00607182; iTF_00525264; iTF_00501905; iTF_00482354; iTF_00557299; iTF_00564755; iTF_00574165; iTF_00583061; iTF_00513561; iTF_00511386; iTF_00566908; iTF_00576444; iTF_00619964; iTF_00495229; iTF_00570493; iTF_00496734; iTF_00598974; iTF_00610015; iTF_00597504; iTF_00481635; iTF_00550344; iTF_00580072; iTF_00539753; iTF_00515690; iTF_00619243; iTF_00546060; iTF_00566188; iTF_00615661; iTF_00488114; iTF_00591794; iTF_00539059; iTF_00477429; iTF_00504086; iTF_00614999; iTF_00476024; iTF_00498980; iTF_00917318; iTF_00562568; iTF_00589640; iTF_00472457; iTF_00509199; iTF_00553807; iTF_00595343; iTF_00614288; iTF_00520730; iTF_00556607; iTF_00602697; iTF_00338508; iTF_00805292; iTF_00802953; iTF_00803703; iTF_00527406; iTF_00337680; iTF_00804498; iTF_01555506; iTF_00336883; iTF_00494483; iTF_00512105; iTF_00588243; iTF_00588244; iTF_00618515; iTF_00571266; iTF_00604199; iTF_00503370; iTF_00555947; iTF_00612178; iTF_00555187; iTF_00523797; iTF_01319861; iTF_00606424; iTF_00490177; iTF_00478114; iTF_00489475; iTF_00565475; iTF_00561860; iTF_00581638; iTF_00592486; iTF_00483079; iTF_00486663; iTF_00536872; iTF_00548168; iTF_00525961; iTF_00605674; iTF_00480267; iTF_00533196; iTF_00531757; iTF_00596750; iTF_00593935; iTF_00609263; iTF_00612911; iTF_00504787; iTF_00541171; iTF_00594645; iTF_00604949; iTF_00578646; iTF_00609270; iTF_00617752; iTF_00488762; iTF_00491610; iTF_00607866; iTF_00571995; iTF_00507708; iTF_00524511; iTF_00590335; iTF_00919160; iTF_00919910; iTF_00916337; iTF_00914610; iTF_00915446; iTF_00918265; iTF_00530362; iTF_00588937; iTF_00509915; iTF_00529660; iTF_00493054; iTF_00541856; iTF_00552416; iTF_00500420; iTF_00535430; iTF_01551094; iTF_01558395; iTF_01550372; iTF_01548953;
90% Identity
iTF_01550372;
80% Identity
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