Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 6.7e-05 0.54 10.3 0.0 14 48 66 100 60 103 0.88

2 7 0.0017 13 5.8 0.4 20 45 103 128 97 137 0.81

3 7 0.028 2.3e+02 1.9 0.4 20 45 131 156 128 159 0.80

4 7 0.0017 13 5.8 0.6 16 45 155 184 142 188 0.85

5 7 0.0015 12 6.0 0.9 17 44 184 211 180 214 0.89

6 7 0.00068 5.5 7.1 0.1 21 44 216 239 212 243 0.89

7 7 0.0032 25 4.9 0.2 21 45 244 268 241 274 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	6.7e-05	0.54	10.3	0.0	14	48	66	100	60	103	0.88
2	7	0.0017	13	5.8	0.4	20	45	103	128	97	137	0.81
3	7	0.028	2.3e+02	1.9	0.4	20	45	131	156	128	159	0.80
4	7	0.0017	13	5.8	0.6	16	45	155	184	142	188	0.85
5	7	0.0015	12	6.0	0.9	17	44	184	211	180	214	0.89
6	7	0.00068	5.5	7.1	0.1	21	44	216	239	212	243	0.89
7	7	0.0032	25	4.9	0.2	21	45	244	268	241	274	0.85

Coding Sequence: ATGGAGCAAGTGATTGATGTTGGTTGTGTCAAGGAGGAGCACTGTGAGGCAATCTGCAATATGTTCAGGACTCAGGATTGGCAATTAACAATGCGACATAGGGACTTAGGAATCGTGAAAATCGAACAGGACATGAGCATAGTCTGGCAAAGCACTAGCACTGCCACTGTGGACAATAAAGCAGCACATTTGGACAAACAAAAGAACGTCACATCCAGCGATAAACCATTTAAGTGTCCACATTGTACTAAGGATTTTGCCACAAGCAGCAATCTAAAGGTTCATCTCTCACGCACTCACTCCGGCGACCAGGAGCGTCCCTTTGAGTGCCCAACCTGCCCGAAGTCATTCGCCACCAATGACAACCTGCAAAAACATATTCGCAGGCATTCGAATGAGCGAAACCTCAATTGTCCACACTGCCCCAAGGCTTTTGCCACCAAGGACAATCTGCAGAAACACATTCGCCGTCACTCGAGCGAGCGCAACCACAATTGTCCGCATTGTCCCAAGGCATTTGCAACCAATGACAATCTGCAGAAGCACATCCGACGGCACTCGAGCGAAAGAAATCTACAATGCCCACACTGCCCCAAGGCTTTTGCGACAAACGATAATCTCCAGCGACACATACGTGGCCACACTGGCGAGCGTCCCTTTAAGTGTCCCTACTGCCCGAAACCGTTTGCCCAAAACAGAGATCTGAAGGCGCACATCTTGGAGCATACCGGGGAAAAGCCCTTCAAATGTCCGCACTGCCCCAAGGCGTGTGTGCGCAGCGAAGGACTAAAGAAACATATTTCGCGACTTCACAAAGATGTGGAGCCGCAAACGGTGGAGATTACGGCAGCTAAACAATGGCAGATACCGACCGAGGTCAAGTCCTACATCAACGATGCCAATGGCAGAGTCCTAATGTACAAATATGATCTGGCTAAGCAGACACGAATGCCCACAGGAGAGGCGTAA
Protein Sequence: MEQVIDVGCVKEEHCEAICNMFRTQDWQLTMRHRDLGIVKIEQDMSIVWQSTSTATVDNKAAHLDKQKNVTSSDKPFKCPHCTKDFATSSNLKVHLSRTHSGDQERPFECPTCPKSFATNDNLQKHIRRHSNERNLNCPHCPKAFATKDNLQKHIRRHSSERNHNCPHCPKAFATNDNLQKHIRRHSSERNLQCPHCPKAFATNDNLQRHIRGHTGERPFKCPYCPKPFAQNRDLKAHILEHTGEKPFKCPHCPKACVRSEGLKKHISRLHKDVEPQTVEITAAKQWQIPTEVKSYINDANGRVLMYKYDLAKQTRMPTGEA

Sequence clustering based on sequence similarity using MMseqs2