Basic Information

Gene Symbol
-
Assembly
GCA_018904105.1
Location
JAEIFR010000295.1:8748221-8752837[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 25 0.002 0.14 12.5 2.3 1 23 216 238 216 238 0.98
2 25 0.012 0.81 10.1 3.1 1 23 244 266 244 266 0.97
3 25 0.11 7.6 7.1 0.4 2 23 298 319 297 319 0.96
4 25 0.0097 0.67 10.4 1.3 1 23 393 416 393 416 0.93
5 25 1.6 1.1e+02 3.4 1.5 2 22 427 447 426 447 0.95
6 25 0.023 1.6 9.2 1.8 1 23 491 513 491 513 0.98
7 25 0.019 1.3 9.4 0.9 2 23 592 614 591 614 0.95
8 25 0.00029 0.02 15.2 0.1 1 22 622 643 622 643 0.96
9 25 0.046 3.2 8.2 4.3 1 23 652 675 652 675 0.96
10 25 0.0078 0.54 10.7 0.2 2 23 705 726 704 726 0.97
11 25 1.1e-05 0.00073 19.7 2.5 1 23 734 756 734 756 0.98
12 25 0.027 1.9 9.0 1.6 1 23 910 933 910 933 0.94
13 25 0.0024 0.17 12.3 2.9 2 22 941 961 941 961 0.96
14 25 0.34 24 5.5 0.4 1 23 970 993 970 993 0.89
15 25 2.4e-05 0.0017 18.6 4.6 1 23 1019 1041 1019 1041 0.98
16 25 0.0004 0.027 14.8 0.7 1 23 1048 1070 1048 1070 0.98
17 25 0.013 0.87 10.0 0.0 2 22 1097 1117 1096 1117 0.95
18 25 0.072 5 7.6 5.2 1 23 1162 1185 1162 1185 0.96
19 25 0.0053 0.37 11.2 2.7 1 23 1222 1245 1222 1245 0.97
20 25 0.001 0.072 13.4 3.9 1 23 1269 1292 1269 1292 0.97
21 25 1e-05 0.00071 19.7 0.1 2 23 1317 1338 1316 1338 0.95
22 25 0.00021 0.014 15.7 3.1 1 23 1344 1366 1344 1366 0.99
23 25 2.8e-06 0.00019 21.5 2.7 1 23 1372 1394 1372 1394 0.97
24 25 5.1e-08 3.5e-06 27.0 2.4 1 23 1400 1422 1400 1422 0.99
25 25 0.0012 0.086 13.2 0.3 1 22 1428 1449 1428 1452 0.91

Sequence Information

Coding Sequence
ATGTTGCCGACAGATATATGTCGCACTTGTGCACGCCAAGCTGACAATCTGCTGGCGCTTTCAATGTGCATTGAAAAATACATGAACAAAAGAATAAGCGATATGCTACACGAATTGACTCACAACGATCCAATGGAACTCGCAACTGATGATCTGCCTGAAAACCTTTGCGAAGACTGCTTGCACCAGCTGCAAAATGCCTATGGTTTTGTGTTGCAGGCACGTCAGGCGCAGGAGCAATTGTTGCTTAAACTACGCAAGGAATTGCTGTCACCAAAATGCTTAGATGAGACACCTATCGAAATGGCAGTGCAGCCTATTAAGACTGAATCAGACCTTGAATTTGGTGAGGAAACTGAAAATGCTGATCAAATGGACCCAGAGGACGATTGTGCAGTTAGTCCACTTGTTTGTGTTGCAGCGTTAAAATTGCAACCAGAAAGTGACAGTGATAGTAACCGCGACGATGCAGACTGTAAGGATCTCCAACCCATGCAACTGAGGCGAAGTGTGCGCAATGCCAAACCTTCAAACAGCAGCGAAGATGAAGCAGCATCTGGAAGCACAAATCCAACACCAATAAAACGTAGGCGTGGCCGTCCAGCTCGTGTCACTAAGGATCAAACAACAAATGAAGAAGGACGTTTTACTTGCGACGTCTGCCAGAAAACGTTCTCATGGCACCGCGACATGCAACGTCATGCCCGCATCCACTACGAGAAGCCGTCTCATGTGTGCGAGAACTGTGGAAGGAGTTTCTTGCGTAAGGACAAGTACATATTTCATATGCGCACTCATGAGAAGCATCGTGCCAAATCCCATACCCCAACGCTGAACCTGGAGTGGCAATTCGCTGAGCGGCTGTATAGTTCAGGACTACTAAAAAGTGTTGAATGTAAGCTGTGCGGCTTAAGGTGTCAACGCATTCTGGAGCTGCGTGAGCATATTGCTAGCCATGCCAGACCTGAAACGTTGTCCGATCTTAGTCCCGAAAGCGAAGTTATCAGAGAACAGTTTCCCAACCATAAAGACATGACACAAATCAGGCAACTGGTGTGTGCAGACATTGCTAAAGGACGGGAGTACCTGGATAAATACTGTTCAGTGGTTAATATCCATGGTTATGAGCTCTGCCTGAGTGATTCCGACGAGGAAATTCTTGGCATAACGCCTCCTTATAAATGCTTACCCTGTAACGCATCTTTTACTCGCAAATATCGTTTAATGCGTCACACACTAGAGTCGCACACACCATCAAATAATGAAGCTGACTGGCAGCGTTGCAATAAATGCAAAATTGGCTTTGTATGTGTAAAGTTGTTGGAGCAGCATCAGCGTACCCAGTGTTACAGTCAATTCAAGCGCTATAGCTGTACTGACTGTCCAGGCAAATTTTTATGGCAACAAAATCTCAAACTGCACGATTGCTGCAGGGGAAACAGGATTGCAGCGGATGAAGACCGTCGTCAGTTCTATTGTTGTCTGTGTGATGAGCAATTGGAAAGCATGTCGTCTCTGAGAAGCCACTTACTCACCCATCGGGATGGACGCACTGGCATAGATCAAAAACAATCTTCTACATTTTTTCGTTACTTTTATCCCAATGGCCTGGATTGTAACTGGACGGAACTAAGTGGGCGCATTGCGAATGATTTTGAAGTTGGGGATTATGGAAGATATTTTAATGCCTGTACAGCTGCTGGCCAGGAGCTAGACTTCTTAGCTTCGGATACTGACTTAAGTGATAATGAAACAACATCCTCAGTGGTGCTTACTTGTGATTTGTGTGGCGGGGCAACCACTCGCCTTACCTATTTGCATCGTCATCAAGAAAGTCAACATAGTGAGCTAAAGTCCATGCCTCATGTTTGTGCCACTTGTGGAAAAGGATTTGTTGCTAGATCATTGCTTCAGTGGCATCTTCGAACAGTATGCTGCAAGCAACATACAAATTATAAGTGTACGGACTGCAACCTTTGCTTTGTATGGCGGTCGAACCACGAGCGGCATATGAAGTTAGTGCACGAAAAGGTGATTGACGATGAGAGAGCGGAAGAGTTCAAACAGGTACTCCGGTTAAAGCCGAAACGTCAGCAGCCAATGGCCAAGCTGCAGTGCGGCGAATGCGAAAAGCTTTTCATTTGGCCGAAGGATCTAACCCGTCACAAACGCATTCATCAGTTGCAAACGGCGGCACAATATGATTGTTCCTTTTGCCAACGCAAGTTTTACCGAAAGGATGGGCTTAAGTCTCATATGCGGGTGCATGGAGAGCAACTGCAGCTGGAAACGAGCAGTAAATCAATTGGTAATCCAGATACTGCTATATTGCAAAATATGCCTGTTGTTTTGTCCCAACTATGCCGTCCCAATGGTTGCAAGCAAATAAAATGCATGATTTGTGCATCTTACCATACAAAGATTGCCGATCTACGCACCCATATAATTTCACATCAATTCGCGTTGCCTCCATTTAAGCATGCAAATACGGAAGAGATTGAAACCACTTGCCGCACACTATATCCGGAATTAGAATGTAATGATATGGACAGAGAACAATTAATTCAGCGCATTCAATTTGATCTAGCTAAAGGTGATGAACTCGAAAGATTCGTTTCAATTACAAATGAGGCAGGTATTGAGCTAAGCTTGGATAGTAGCGAAACCGAAACTGATTCGGACTCCACGGAATCTACCGAAAGAAACAGTAGAACTGCAAGCCGAACATACGACTGTGATCTGTGCCAACTAAAAGTGTCACGCAAACACAAACTTTATGCACACCAACTGGAGCAGCATGCTTGGCAAGAAGCAAGTCGTGTCTGCAGCCATTGCCAGGCAAGATTCGTTAATAAACACTTGCTGGAACATCATTATCGCACACTTTGCCGCAATGGCCTTAAGCGTTTCCTTTGCCGAAAGTGCCCCCTACGTTTTCGCTGGCGCAACAACCTCAAGTTACACGCGGATATTGCGCATCCGGAAGTTGTCACTGAGAAACAGCCGAATACAGGAATCCAATTGACTGGAACAAGTTTGCTACCGGTCGTCAGCTATGAATGTCACGAGTGTAAACGTAGCTTTAAAATGCAGAAGGATCTTACACGCCACAAGTTGATGCATGCCCAAGAATCGAGCATTTATCGTTGTCGCTGGTGTGCCAGGCGCTTTTATCGAGAGGCCAATCTTCTACAGCATATTGAGCGCCATGGCATTAATGCTGCTCAACTGCCTTACGCGGAGACCTTGCTAAATGCAAGCCGGCATCCGAATGGGTTAAAGTGCATTCAGTGCAAGGTGTGCAATGTGCAATTTGCCACCATTGCCGCACTGCGCTCACATTTGATGACAGCCCCCAGCGGAACACACCACGATGCCGAGTCAATGCTTAACTACTCGATTACCAACCAGTTTGGCTATGAGCTTCATCTAGAAGACTCGGAAACTGATGATGAGGCGAAACCTCCTGGCACACCACCACAATACACTTGCGGCATGTGTCAATTGCGTTGTAAGCGAAAATATGAGATGCATCAGCACCAGCAAGCGATGCATCGACTGGAACGGATAAGCGATGGCTGTGATCAATGCATTTTCAAGAGTGTTTCAGCTGACCTGATTGCCTACCACAAACGAGTGCAATGCAGCAATCTTGAGAAACAATTCAAATGTTCAAAATGTGGATATAAGTTTATGTGGGAATCAAATTTGTCGCTGCACATGCATCGAGAGCACTCAAACTGCAACATCCAGGCAAAGGAGGAGACTGTATCAGGCTCAGTTGAGAGTACCAGCAGCCAGACCTTTAAGTGCGGTCAGTGCCCACGTAAATACAATCGAAAGGATCGGTTGACTGCCCATGTAAAGAAGTGTCATGCACCAAACGCGATTGCTTTAAAAAAAACAACGAAGACGACATCAAGCGTGGCCAAACAGCAGAAAACTTTCCTATGTGCCTTTTGTGGCAAAGCCGTGAGCTCCTCCTCGAATCTGATCGTACACATACGACGTCACACTGGCGAGAAACCATTTAAATGCGACTTTTGTGACATGGCTTTTCCACGCTCCTCTGATCTTCAGTGTCATCGACGCACCCACACAGGCGAACGGCCCCACGTTTGCACGGTGTGCCAAAGGGGATTTTCGCGCTCATACAAGCTGCAGCAACACATGCGCATTCATAACGGCGAACGACCCTACAAATGTACCTATTGTGACAAGAGCTTTACACAGTCCAATGACCTGACACTCCACATCCGTCGGCACACAGGAGAACGGCCCTATCAGTGCGGCACCTGCGGCGAACGGTTTATCCAGGGCACAGCCCTTAAGAACCATCGTCAGCAGACTGGACACAAAGATAATACCGAGGATCAACCTAAAACTAACTAA
Protein Sequence
MLPTDICRTCARQADNLLALSMCIEKYMNKRISDMLHELTHNDPMELATDDLPENLCEDCLHQLQNAYGFVLQARQAQEQLLLKLRKELLSPKCLDETPIEMAVQPIKTESDLEFGEETENADQMDPEDDCAVSPLVCVAALKLQPESDSDSNRDDADCKDLQPMQLRRSVRNAKPSNSSEDEAASGSTNPTPIKRRRGRPARVTKDQTTNEEGRFTCDVCQKTFSWHRDMQRHARIHYEKPSHVCENCGRSFLRKDKYIFHMRTHEKHRAKSHTPTLNLEWQFAERLYSSGLLKSVECKLCGLRCQRILELREHIASHARPETLSDLSPESEVIREQFPNHKDMTQIRQLVCADIAKGREYLDKYCSVVNIHGYELCLSDSDEEILGITPPYKCLPCNASFTRKYRLMRHTLESHTPSNNEADWQRCNKCKIGFVCVKLLEQHQRTQCYSQFKRYSCTDCPGKFLWQQNLKLHDCCRGNRIAADEDRRQFYCCLCDEQLESMSSLRSHLLTHRDGRTGIDQKQSSTFFRYFYPNGLDCNWTELSGRIANDFEVGDYGRYFNACTAAGQELDFLASDTDLSDNETTSSVVLTCDLCGGATTRLTYLHRHQESQHSELKSMPHVCATCGKGFVARSLLQWHLRTVCCKQHTNYKCTDCNLCFVWRSNHERHMKLVHEKVIDDERAEEFKQVLRLKPKRQQPMAKLQCGECEKLFIWPKDLTRHKRIHQLQTAAQYDCSFCQRKFYRKDGLKSHMRVHGEQLQLETSSKSIGNPDTAILQNMPVVLSQLCRPNGCKQIKCMICASYHTKIADLRTHIISHQFALPPFKHANTEEIETTCRTLYPELECNDMDREQLIQRIQFDLAKGDELERFVSITNEAGIELSLDSSETETDSDSTESTERNSRTASRTYDCDLCQLKVSRKHKLYAHQLEQHAWQEASRVCSHCQARFVNKHLLEHHYRTLCRNGLKRFLCRKCPLRFRWRNNLKLHADIAHPEVVTEKQPNTGIQLTGTSLLPVVSYECHECKRSFKMQKDLTRHKLMHAQESSIYRCRWCARRFYREANLLQHIERHGINAAQLPYAETLLNASRHPNGLKCIQCKVCNVQFATIAALRSHLMTAPSGTHHDAESMLNYSITNQFGYELHLEDSETDDEAKPPGTPPQYTCGMCQLRCKRKYEMHQHQQAMHRLERISDGCDQCIFKSVSADLIAYHKRVQCSNLEKQFKCSKCGYKFMWESNLSLHMHREHSNCNIQAKEETVSGSVESTSSQTFKCGQCPRKYNRKDRLTAHVKKCHAPNAIALKKTTKTTSSVAKQQKTFLCAFCGKAVSSSSNLIVHIRRHTGEKPFKCDFCDMAFPRSSDLQCHRRTHTGERPHVCTVCQRGFSRSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCGTCGERFIQGTALKNHRQQTGHKDNTEDQPKTN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01554842;
90% Identity
iTF_01554842;
80% Identity
-