Basic Information

Gene Symbol
Aef1
Assembly
GCA_018903425.1
Location
JAEIGD010000009.1:941585-942675[-]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.012 82 3.7 0.1 22 46 43 67 38 69 0.86
2 4 1e-05 0.074 13.4 0.0 21 52 70 101 68 102 0.89
3 4 0.012 82 3.7 0.1 21 48 98 125 96 129 0.85
4 4 3.3e-05 0.24 11.8 0.1 21 47 126 152 124 159 0.88

Sequence Information

Coding Sequence
ATGATGCATATTAAGAGCCTGCCACACGCACATCAGGCCGCTGCGGCAATGAGCAATTGTGACATTGGTAATGGCTCGAGCAGCAGTGGTGGCGGCGGCGGCGGTGGTGGTGGTGGCCGAGAACAGGATAAGCCGTTCCATTGCACTGTTTGCGATAGACGCTTCAGGCAACTGAGCACACTAACCAACCATGTGAAAATCCATACCGGGGAAAAGCCCTATAAATGCAACGTTTGTGATAAGACGTTCCGTCAGTCGTCGACTTTGACGAATCATCTGAAAATTCATACGGGCGAAAAGCCTTACAATTGCAACTATTGCCCCAAGCATTTCCGCCAGCTGAGCACATTGGCCAATCATGTCAAGATTCACACGGGTGAAAAGCCGTTCGAGTGCGTCATATGCAAGAAACAGTTCCGGCAATCCAGCACGCTCAACAATCACATAAAAATCCACGTCATGGACAAGGTCTACGTTCCTGTGAAGATCAAAACCGAGGAGGACGAGGGGTGA
Protein Sequence
MMHIKSLPHAHQAAAAMSNCDIGNGSSSSGGGGGGGGGGREQDKPFHCTVCDRRFRQLSTLTNHVKIHTGEKPYKCNVCDKTFRQSSTLTNHLKIHTGEKPYNCNYCPKHFRQLSTLANHVKIHTGEKPFECVICKKQFRQSSTLNNHIKIHVMDKVYVPVKIKTEEDEG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01557036;
90% Identity
iTF_01557036;
80% Identity
iTF_01557036;