Basic Information

Insect: Zaprionus nigranus
Gene Symbol: zfh1
Assembly: GCA_018903425.1
Location: JAEIGD010000003.1:3376602-3400599[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.022 2 9.3 1.5 2 23 79 101 78 101 0.95

2 9 0.0012 0.11 13.3 0.1 2 23 232 253 231 253 0.95

3 9 1.3e-05 0.0012 19.5 0.6 2 23 267 288 266 288 0.97

4 9 5.9e-05 0.0054 17.4 6.0 1 23 297 319 297 319 0.99

5 9 0.00019 0.017 15.8 1.4 3 21 327 345 325 346 0.94

6 9 0.0063 0.57 11.0 0.7 2 21 584 603 583 604 0.92

7 9 9.1e-06 0.00083 19.9 0.7 1 23 953 975 953 975 0.94

8 9 6.4e-05 0.0058 17.3 7.3 1 23 981 1003 981 1003 0.98

9 9 0.0023 0.2 12.4 4.3 1 21 1009 1029 1009 1030 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.022	2	9.3	1.5	2	23	79	101	78	101	0.95
2	9	0.0012	0.11	13.3	0.1	2	23	232	253	231	253	0.95
3	9	1.3e-05	0.0012	19.5	0.6	2	23	267	288	266	288	0.97
4	9	5.9e-05	0.0054	17.4	6.0	1	23	297	319	297	319	0.99
5	9	0.00019	0.017	15.8	1.4	3	21	327	345	325	346	0.94
6	9	0.0063	0.57	11.0	0.7	2	21	584	603	583	604	0.92
7	9	9.1e-06	0.00083	19.9	0.7	1	23	953	975	953	975	0.94
8	9	6.4e-05	0.0058	17.3	7.3	1	23	981	1003	981	1003	0.98
9	9	0.0023	0.2	12.4	4.3	1	21	1009	1029	1009	1030	0.96

Sequence Information

Coding Sequence: ATGTTGTCCTGTTTGGCGCCATCGTCGACACGTTTTGGCCAAGAGGATAACATTATACAGCAGAGCATGCCATCATCCACAGCCTTCTCCATGCAGTTTCCCTCTTTGGCCTCCAGTCTACACCATCACCAAGCACACAGCAAGCCCAGCAATGTGGCTGCCCCAAGCGAGGAGGAGGAACACGGTCATCACACCGCCAGCACGATGGGCAGCGCAGGCGAGGATTACCTGGTCAAGTGCACGCAGTGCCACCAGCGCTTTAATGAGTTCCAGTCCCTTAGCGATCACATTGCCAGCGAACATCCGCACGACAAGCTCAACTACGAGCCGAGTCTGCGTGCTGCGGGCGCAGTGCAGCCCGAGAGCGAGGCGGAGGAGGACGAACAGAGCAATTTGAGCTGCAGCAGTCGCCGCTACGCCAAGTCGCCGTCGAGCAGCAGCAACAACAACAACAACAGTGAAACAACTAAAAACCAAAATCAGAACCCGAGCAACAGCAACAGTCGCTCGCCGCTCTGCTCACCTGTTGTTGTTGCCGCAACGCACCCGGCGCACTCGAGCGATCTATTTGCCCACCTGCCGCACCCGCCACCACAGCTGCCAGCCCACTTGCATGCCCAGTTCATGGCAGCCGCCGCCTCCCTGGCCATGCACCCCGGCTCGACGACGGGCGATCTCGGCGGTTCCGCCATTCCCTGCATGCAGTGCACCGCGTCCTTTGCGACCCGCGAGCAACTCGAGCAGCATCAGCTGCTGCACTCCCCCAGCGGGCAGCCAACAACCCACAACGTGACGCAGACATGCAAAATATGCAACAAGGCGTTCGCGAATGTTTACCGCCTGCAGCGGCACATGATCAGCCACGACGAGTCGGCGCTGCTGAGGAAATTCAAGTGCCAACTGTGCGAGAAGGCGTTCAAGTTCAAGCACCACCTGAAGGAGCACGTGCGCATCCATTCCGGCGAGAAGCCCTTCGGCTGCGACAAGTGCGGCAAGCGCTTCTCGCACTCGGGCAGCTTCTCCTCCCACATGACCTCGAAGAAGTGCACCAACATGACCCTCAAAGTGAGCAACCCCACCAACGGCAGCAACACCAGCAGCAGCAGTAATCGGCAGCTCCTCAAGAGCTTGGATAAAAATGCCAATGCTGGACGCTCTCCCTCAGATCTGCAGCCACTGTTGCCGGGCAAGCGAGGGTGCAAACTGCCCGATCCGCTGCTGCCCAATCCCATGAACTACTTTGCGGGAGAGGCACAGATGTCGGTGCCGGCGGGGCCCAATGGACCCGGAGCCTTCTATCCCAATTACAGTGCCATGAACGCGGCCTTGATGGCATTCCCAAATGCCTTTATGGCCGCTCTGGACCCACGCATGCATCCGTTTGGCATACAGCGACTGCTGGAGATGACAGCCGTCGGGCAACAGCATCGTGAGGTGCAGCATCAGCAGCAACAGCAGCAGCACGAGGAGCCGCTGTACGAGCCCAGCAAGGATGAGGATGAGACGCCCGATGAACCCAAGCTGGTAATGGATCTCGGGGACTCCGAGATCAAGCCAGCGACACCAGCTCCAGAGACGCCCGCGGTTGCTGAGCCAGTTGCCGATGCCGGCTCGTTCAAGCAGGAGCCCAGCCGGGAGCCAACGCCTGTGCTGGAGAGTGCTCCAGGCACGCCCAAGTCCATCAAAGTAGAGCAGGAGGAGGAAGCGGCGCCTGCAGAGGAGTCGCGTGCCCAAACCCCACAAGATCTGCGCTGCAGTCGCTGCTCAAAGCAATTCAATCATCCAACTGAGCTGGTACAGCACGAGAAGGTTCTCTGCGGGCTTATCAAAGAGGAGCTGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGCGGACGAGGATGATGAGGAGGAGGAAGAGCCACGCCAGGACTTTAATGCCGGCAGCAGCGACAGCGGCGAACGCAAGGTGCGCGTACGCACCGCCATCAACGAGGAGCAGCAGCAGCAGCTGAAGCAACACTACGCCCACAATGCACGTCCGAGTCGGGACGAGTTCCGCCTGATCGCGGCTCGGCTGCAGCTCGACGCGCGTGTCGTGCAAGTCTGGTTCCAGAACAATCGCTCGCGAGAGCGCAAGATGCAGAGCTATGTGAGCAACGGTGAGCAACACGCCGCCGCCGCCACCACGGCAGCAGCTCAGCCACGCGCTGCTGGTGAGGATCAGCCATTGGACTTGTCTGTGAAGCGCGATGCATCGCCACTCTATGGTCTGGCTCCACAGCAGACAACGGCGAGCGAAGCGCCCGTTGACTTTCAGGAGACAATGGCCATCAATCTGAGCCGCAAGCTATCCAGCTCGGCCTCCATGTCGCCGTCCTCGCTGTCACCCTGCTCGGGTGCCTCGTCGCTGCAGCAATCGGCTGCTGCTGCCGCCGCTGCGGCCATCTACTTTGCCCCGCCCTCGCCGCCCAGCTTGCACGAGGCGGCACCCTCGATGCCGCCACATGGGGCAGCCATGGCGCGTGTGCAATCCTTTCCGGGCCTGCCGCCCTACATGATGCCACGCCTGCCCATGGAGGCGCTCTTCCAGATGCGTCCCGGCGGCGAGTACGCGCCCAATCCCCTGATGAACAGTATTAAGCTGCCCGACTATCGCGGCACCAGCCTGAGTCCAGGAGGCTCCGAGAAGCGTTCCTGGCGCGACGACGACTCGCGCATTTCGCACGAGGATGACTACGTGCTGGGCGTTGGCGGCGGACTGCTGCCCCCCAAGCCGAAGCGCGCCAAGGCCGAGACGCATGGCCACGCCGGCGATCCGGATCTGCCCTTTGTGTGCAATCAGTGCGACAAGGCGTTCGCCAAGCAGAGCTCCCTGGCGCGTCACAAATACGAGCATTCCGGTCAGCGTCCCTATCAGTGCATGGAATGTCCCAAGGCGTTCAAGCACAAGCACCACTTGACGGAGCACAAGCGTCTGCACTCTGGGGAGAAGCCCTTCCAGTGCTCCAAGTGCTTGAAACGCTTCTCCCACTCGGGCAGCTACAGCCAGCACATGAACCACCGTTACTCCTACTGCAAGCCATACAGGGAATAG
Protein Sequence: MLSCLAPSSTRFGQEDNIIQQSMPSSTAFSMQFPSLASSLHHHQAHSKPSNVAAPSEEEEHGHHTASTMGSAGEDYLVKCTQCHQRFNEFQSLSDHIASEHPHDKLNYEPSLRAAGAVQPESEAEEDEQSNLSCSSRRYAKSPSSSSNNNNNSETTKNQNQNPSNSNSRSPLCSPVVVAATHPAHSSDLFAHLPHPPPQLPAHLHAQFMAAAASLAMHPGSTTGDLGGSAIPCMQCTASFATREQLEQHQLLHSPSGQPTTHNVTQTCKICNKAFANVYRLQRHMISHDESALLRKFKCQLCEKAFKFKHHLKEHVRIHSGEKPFGCDKCGKRFSHSGSFSSHMTSKKCTNMTLKVSNPTNGSNTSSSSNRQLLKSLDKNANAGRSPSDLQPLLPGKRGCKLPDPLLPNPMNYFAGEAQMSVPAGPNGPGAFYPNYSAMNAALMAFPNAFMAALDPRMHPFGIQRLLEMTAVGQQHREVQHQQQQQQHEEPLYEPSKDEDETPDEPKLVMDLGDSEIKPATPAPETPAVAEPVADAGSFKQEPSREPTPVLESAPGTPKSIKVEQEEEAAPAEESRAQTPQDLRCSRCSKQFNHPTELVQHEKVLCGLIKEELXXXXXXXXXXXXXXXXXXXXXXXXXXADEDDEEEEEPRQDFNAGSSDSGERKVRVRTAINEEQQQQLKQHYAHNARPSRDEFRLIAARLQLDARVVQVWFQNNRSRERKMQSYVSNGEQHAAAATTAAAQPRAAGEDQPLDLSVKRDASPLYGLAPQQTTASEAPVDFQETMAINLSRKLSSSASMSPSSLSPCSGASSLQQSAAAAAAAAIYFAPPSPPSLHEAAPSMPPHGAAMARVQSFPGLPPYMMPRLPMEALFQMRPGGEYAPNPLMNSIKLPDYRGTSLSPGGSEKRSWRDDDSRISHEDDYVLGVGGGLLPPKPKRAKAETHGHAGDPDLPFVCNQCDKAFAKQSSLARHKYEHSGQRPYQCMECPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01549047;
90% Identity: iTF_01549047;
80% Identity: iTF_01556729;