Zlac009164.1
Basic Information
- Insect
- Zaprionus lachaisei
- Gene Symbol
- zfh1
- Assembly
- GCA_018901815.1
- Location
- JAEIFI010000587.1:515856-540216[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.017 1.2 9.6 1.5 2 23 79 101 78 101 0.95 2 9 0.00026 0.018 15.3 0.2 1 23 124 146 124 146 0.97 3 9 1e-05 0.0007 19.8 0.6 2 23 160 181 159 181 0.97 4 9 0.0001 0.0072 16.6 5.5 1 23 190 212 190 212 0.98 5 9 0.00015 0.011 16.0 1.4 3 21 220 238 218 239 0.94 6 9 0.0072 0.5 10.8 0.8 2 20 442 460 441 462 0.92 7 9 7.2e-06 0.0005 20.2 0.7 1 23 771 793 771 793 0.94 8 9 3.6e-05 0.0025 18.0 7.4 1 23 799 821 799 821 0.98 9 9 0.0018 0.12 12.7 4.3 1 21 827 847 827 848 0.96
Sequence Information
- Coding Sequence
- ATGTTGTCCTGTTTGGCGCCATCGTCGACACGTTTTGGCCAAGAGGATAACATTATACAGCAGAGCATGCCATCGTCCACAGCCTTCTCCATGCAGTTTCCCTCTTTGGCCTCCAGTCTGCACCATCATCAAGCACACAGCAAGCCCAGCAATGTGGCTGCCCCAAGCGAGGAGGAGGAACACGGCCCGCACACAGCCAGCACGATGGGCAGCGCAGGCGAGGATTACCTGGTCAAGTGCACGCAGTGCCACCAGCGCTTCAATGAGTTCCAGTCCCTTAGCGAGCACATTGCCAGCGAACATCCGCACGACAAGCTCAACTACGAGCCGAGTCTGCGCTCGACGACGGGCGATCTCAGCGGCGCCGCCTTTCCCTGCATGCAGTGCACCGCGTCCTTTGCGACCCGCGAGCAACTCGAGCAGCATCAGCTGCTGCACTCCCCCAACGGGCAGCCAACAACCCACAACGTGACGCAGACATGCAAAATATGCAACAAGGCGTTCGCGAATGTTTACCGCCTGCAGCGGCACATGATCAGCCACGACGAGTCGGCGCTGCTGAGGAAATTCAAGTGCCTACTGTGCGAGAAGGCGTTCAAGTTCAAGCACCACCTGAAGGAGCACGTGCGCATCCATTCCGGCGAGAAGCCCTTCGGCTGCGACAAGTGCGGCAAGCGCTTCTCGCACTCGGGCAGCTTCTCCTCCCACATGACCTCGAAGAAGTGCACCAACATGACCCTCAAAGTGAGCAACCCCAGCAACGGCAGCAACACCAGCAGCAACAGCAGTAATCGGCAGCTCCTCAAGAGCTTGGATAAAAATGCCAATGCTGGACGCTCTCCCTCAGATCTGCAGCCACTGTTGCCGGGCAAGCGAGGCTGCAAACTGCCCGATCCGCTGCTGCCCAATCCCATGAACTACTTTGCGGGAGAGGCACAGATGTCGGTGCCGGCGGGGCCCAATGGACCCGGAGCCTTCTATCCCAATTACAGTGCCATGAACGCGGCCTTGATGGCATTCCCGAATGCCTTCATGGCCGCTCTGGACCCACGCATGCATCCCAAGGATGAGGATGAGACGCCCGATGAACCCAAGCTCGTAATGGATCTCGGGGACTCCGAGGTCAAGCCAGCGACACCAGCTCCAGAGACGCCCGCGGTTGCTGAACCAGTTGCCGATGCCGGCTCGTTCAAGCAGGAGCCCAGCCGGGAGCCAACGCCTGTGCTGGAGAGTGCTCCAGACACGCCCAAGTCCATCAAAGTAGAGCAGGAGGAGGAAGCGGCGCCTGCAGAGGAGCCGCGTGCCCAAACCCCACAAGATCTGCGCTGCAGTCGCTGCTCAAAGCAATTCAATCATCCAACTGAGCTGGTGCAGCACGAGAAGGATGATGAGGAGGAGGAAGAGCCACGCCAGGACTTTAATGCCGGCAGCAGCGACAGCGGCGAACGCAAGGTGCGCGTACGCACCGCCATCAACGAGGAGCAGCAGCAGCAGCTGAAGCAACACTATGCCCACAATGCACGTCCGAGTCGGGACGAGTTCCGTCTGATCGCGGCTCGGCTGCAGCTCGACGCGCGTGTCGTGCAAGTCTGGTTCCAGAACAATCGCTCGCGGGAGCGCAAGATGCTGAGCTATGTGAGCAACGGTGAGCAACACGCCGCCGCCACCACGGCAGCAGCTCAGCAACGCGCTGCTGGTGAGGATCAGCCATTGGACTTGTCTGTGAAGCGCGATGCATCGCCACTCTATGGTCTGGCTCCACAGCAGACAACGGCAAGCGAAGGGCCCGTTGACTTTCAGGAGACAATGGCCATCAATCTGAGCCGCAAGCTATCCAGCTCGGCCTCCATGTCGCCGTCCTCGCTGTCACCCTGCTCGGGTGCCTCGTCGCTGCAGCAGTCGGCTGCTGCTGCCGCCGCTGCGGCCATCTACTTTGCTCCGCCCTCGCCGCCCAGCTTGCACGAGGCAGCACCCTCGATGCCGCCACATGGGGCAGCCGTGGCACGTGTGCAATCCTTTCCGGGCCTGCCGCCCTACATGATGCCACGCCTGCCCATGGAGGCTCTCTTCCAGATGCGACCCGGCGGCGAGTACGCGCCCAATCCGCTGATGAACAGTATTAAGCTGCCCGACTATCGCGGCACCAGCCTGAGTCCAGGAGGCTCAGAGAAGCGTTCCTGGCGCGACGACGACTCGCGCATTTCGCACGAGGATGACTACGTGCTGGCCGTCGGCGGCGGACTGCTGCCCCCCAAGCCGAAGCGCGCCAAGGCCGAGACGCATGGCCACGCTGGCGATCCGGATCTGCCCTTTGTGTGCAATCAGTGCGACAAGGCGTTCGCCAAGCAGAGCTCCCTGGCGCGTCACAAATACGAGCATTCCGGTCAGCGTCCCTATCAGTGCATGGACTGTCCCAAGGCGTTCAAGCACAAGCACCACTTGACGGAGCACAAGCGTCTGCACTCTGGGGAGAAGCCCTTCCAGTGCTCCAAGTGCCTGAAACGCTTCTCCCACTCGGGCAGCTACAGCCAGCACATGAACCACCGTTACTCCTACTGCAAGCCATACAGGGAATAG
- Protein Sequence
- MLSCLAPSSTRFGQEDNIIQQSMPSSTAFSMQFPSLASSLHHHQAHSKPSNVAAPSEEEEHGPHTASTMGSAGEDYLVKCTQCHQRFNEFQSLSEHIASEHPHDKLNYEPSLRSTTGDLSGAAFPCMQCTASFATREQLEQHQLLHSPNGQPTTHNVTQTCKICNKAFANVYRLQRHMISHDESALLRKFKCLLCEKAFKFKHHLKEHVRIHSGEKPFGCDKCGKRFSHSGSFSSHMTSKKCTNMTLKVSNPSNGSNTSSNSSNRQLLKSLDKNANAGRSPSDLQPLLPGKRGCKLPDPLLPNPMNYFAGEAQMSVPAGPNGPGAFYPNYSAMNAALMAFPNAFMAALDPRMHPKDEDETPDEPKLVMDLGDSEVKPATPAPETPAVAEPVADAGSFKQEPSREPTPVLESAPDTPKSIKVEQEEEAAPAEEPRAQTPQDLRCSRCSKQFNHPTELVQHEKDDEEEEEPRQDFNAGSSDSGERKVRVRTAINEEQQQQLKQHYAHNARPSRDEFRLIAARLQLDARVVQVWFQNNRSRERKMLSYVSNGEQHAAATTAAAQQRAAGEDQPLDLSVKRDASPLYGLAPQQTTASEGPVDFQETMAINLSRKLSSSASMSPSSLSPCSGASSLQQSAAAAAAAAIYFAPPSPPSLHEAAPSMPPHGAAVARVQSFPGLPPYMMPRLPMEALFQMRPGGEYAPNPLMNSIKLPDYRGTSLSPGGSEKRSWRDDDSRISHEDDYVLAVGGGLLPPKPKRAKAETHGHAGDPDLPFVCNQCDKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01552672;
- 90% Identity
- iTF_01555312;
- 80% Identity
- iTF_01555312;