Basic Information

Insect: Zaprionus gabonicus
Gene Symbol: zfh1
Assembly: GCA_018903695.1
Location: JAEIFO010001222.1:8283086-8285668[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 9.2e-06 0.00065 19.9 0.6 2 23 25 46 24 46 0.97

2 7 9.5e-05 0.0067 16.7 5.5 1 23 55 77 55 77 0.98

3 7 0.00014 0.0098 16.2 1.4 3 21 85 103 83 104 0.94

4 7 0.0045 0.32 11.4 0.7 2 21 342 361 341 362 0.92

5 7 6.6e-06 0.00046 20.3 0.7 1 23 711 733 711 733 0.94

6 7 3.3e-05 0.0023 18.1 7.4 1 23 739 761 739 761 0.98

7 7 0.0016 0.12 12.8 4.3 1 21 767 787 767 788 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	9.2e-06	0.00065	19.9	0.6	2	23	25	46	24	46	0.97
2	7	9.5e-05	0.0067	16.7	5.5	1	23	55	77	55	77	0.98
3	7	0.00014	0.0098	16.2	1.4	3	21	85	103	83	104	0.94
4	7	0.0045	0.32	11.4	0.7	2	21	342	361	341	362	0.92
5	7	6.6e-06	0.00046	20.3	0.7	1	23	711	733	711	733	0.94
6	7	3.3e-05	0.0023	18.1	7.4	1	23	739	761	739	761	0.98
7	7	0.0016	0.12	12.8	4.3	1	21	767	787	767	788	0.96

Sequence Information

Coding Sequence: ATGTCAGCTGCTCAACTGCTGCCGGCAGTGGGAAGAGCCGGAATGCTGATGAATAAGAGGCAACAACCACAAACTTGCAAAATATGCAACAAGGCTTTCGCGAACGTTTACCGCCTGCAGCGGCACATGATCAGCCACGACGAGTCGGCGCTGCTGAGGAAGTTCAAGTGCCTGCTGTGCGAGAAGGCGTTCAAGTTCAAGCACCACCTGAAGGAGCACGTGCGCATCCATTCCGGCGAGAAGCCCTTCGGCTGCGACAAGTGCGGCAAGCGCTTCTCGCACTCGGGCAGCTTCTCCTCCCACATGACCTCGAAGAAGTGCACCAACATGACCCTCAAGGTGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCTCAAGAGCCTGGACAAAAATGCCAATGCTGGACGCTCTCCCTCAGATCTGCTGCCGGGCAAGCGAGGCTGCAAGCTGCCCGACCCGGTGCTGCCCAATCCCATGAACTACTTTGCGGGAGAAGCACAGATGTCGGTGCAGGCGGGACCCAATGGACCCGGAGCCTTCTATCCCAACTACAGTGCCATGAACGCGGCCTTGATGGCGTTCCCGAATGCCTTCATGGCTGCTCTGGACCCACGCATGCATCCCTTTGGCATACAGCGACTGCTGGAGATGACAGCCGCCGGACAACAGCATCGCGAGGTGCAGCACCAGCACCAGCAGCAACAACAGCAGCAGCACGAGGAGCCTGCTTACGAGCCCAGCAAGGATGACGACGAGACGCCCGATGAGCCCAAGCTTGTAATGGATCTCGAGGAGGCCGAGGCCAAGCCGGCGACACCAGCTCCAGAGGCACCTGCGGTTGTTGAGCCAGTGGCCGATGCCAGCTCGTTAAAGCAGGAGCCCAGCCGGGAACCAACGCCTGTGCTGGAGAGTGCCCCAGCCACGCCCAAGTCCATCAAAGTAGAGCAGGAGGAGGAAGCGGCGCCGGTGGAGGAGTCCCGTCCCCAAACCCCACAAGATCTGCGCTGCAGTCGCTGCTCCAAGCAGTTCAATCATCCAACTGAGCTGGTGCAGCACGAGAAGGTTCTCTGCGGGCTTATCANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGCAGACGAGGATGAGGAGGAGGAGGAAGAGCCACGCCAGGACTTCAATGCCGGCAGCAGCGACAGCGGCGAACGCAAGGTGCGCGTACGCACCGCCATCAACGAGGAGCAGCAGCAGCAGCTGAAGCAACACTACGCCCACAACGCGCGTCCGAGTCGCGACGAGTTCCGCCTGATCGCCGCTCGGCTGCAGCTCGACGCGCGCGTCGTCCAGGTCTGGTTCCAGAACAACCGGTCGCGTGAGCGCAAGATGCAGAGCTACGCGAGCAACGGTGAGCAACACGCCGCCGCCACCTCGGCAGCAGCTCAGCCACGCGCTGCTGGAGAGGATCAGCCGCTGGACTTGTCTGTTAAGCGGGATGCTTCGCCAATCTATGGTCTGGCACCTCAGCAGACAGCCGTGAGCGAAACAGCCGCTGACTTTCAGGAGACAATGGCCATCAATCTGAGCCGCAAGCTGTCCAGCTCGGCCTCCATGTCGCCGTCCTCGCTGTCGCCCTGCTCGGGTGCCTCCTCGCTGCAGCAGTCGGCCGCTGCTGCCGCCGCTGCGGCCATCTACTTTGCGCCGCCCTCGCCGCCCAGCCTGCACGAGGCAGCACCCTCGATGCCGCCACATGGGGCTGCCGTGGCACGTGTGCAATCCTTTCCGGGCCTGCCGCCCTACATGATGCCCCGCCTGCCCATGGAGGCGCTCTTCCAGATGCGACCCGGCGGCGAGTACGCGCCCAATCCGCTGATGAACAGTATTAAGCTGCCCGACTACCGCGGCACCAGCCTAAGTCCAGGAGGCTCGGAGAAGCGTTCCTGGCGCGACGACGACTCGCGCATCTCGCACGAGGATGACTACGTTTTGGGCGTCGGCGGCGGACTGCTGCCCCCCAAGCCGAAGCGCGCCAAGGCCGAGACGCATGGCCATGCTGGCGATCCGGATCTGCCCTTCGTGTGCAACCAGTGCGACAAGGCGTTCGCCAAGCAGAGCTCCCTGGCGCGTCACAAGTACGAGCATTCCGGTCAGCGTCCCTATCAGTGCATGGACTGCCCCAAGGCCTTCAAGCACAAGCACCACTTGACGGAGCACAAGCGTCTGCACTCCGGCGAGAAGCCCTTCCAGTGCTCCAAGTGCCTGAAACGCTTCTCCCACTCGGGCAGCTACAGCCAGCACATGAACCACCGTTACTCCTACTGCAAGCCCTACAGGGAATAG
Protein Sequence: MSAAQLLPAVGRAGMLMNKRQQPQTCKICNKAFANVYRLQRHMISHDESALLRKFKCLLCEKAFKFKHHLKEHVRIHSGEKPFGCDKCGKRFSHSGSFSSHMTSKKCTNMTLKVXXXXXXXXXXXXXXXXXLKSLDKNANAGRSPSDLLPGKRGCKLPDPVLPNPMNYFAGEAQMSVQAGPNGPGAFYPNYSAMNAALMAFPNAFMAALDPRMHPFGIQRLLEMTAAGQQHREVQHQHQQQQQQQHEEPAYEPSKDDDETPDEPKLVMDLEEAEAKPATPAPEAPAVVEPVADASSLKQEPSREPTPVLESAPATPKSIKVEQEEEAAPVEESRPQTPQDLRCSRCSKQFNHPTELVQHEKVLCGLIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXADEDEEEEEEPRQDFNAGSSDSGERKVRVRTAINEEQQQQLKQHYAHNARPSRDEFRLIAARLQLDARVVQVWFQNNRSRERKMQSYASNGEQHAAATSAAAQPRAAGEDQPLDLSVKRDASPIYGLAPQQTAVSETAADFQETMAINLSRKLSSSASMSPSSLSPCSGASSLQQSAAAAAAAAIYFAPPSPPSLHEAAPSMPPHGAAVARVQSFPGLPPYMMPRLPMEALFQMRPGGEYAPNPLMNSIKLPDYRGTSLSPGGSEKRSWRDDDSRISHEDDYVLGVGGGLLPPKPKRAKAETHGHAGDPDLPFVCNQCDKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01552352; iTF_01555312; iTF_01555586; iTF_01560022; iTF_01559662; iTF_01554233; iTF_01553860;
90% Identity: iTF_01552352; iTF_01560022; iTF_01559662; iTF_01554233; iTF_01553860;
80% Identity: iTF_01552352;