Basic Information

Gene Symbol
-
Assembly
GCA_018904595.1
Location
JAEIHA010000905.1:15332336-15347617[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 24 2.8e-05 0.002 18.4 2.1 1 23 132 154 132 154 0.97
2 24 9.1e-06 0.00065 19.9 0.4 1 23 160 182 160 182 0.97
3 24 0.0013 0.096 13.1 0.9 1 23 188 210 188 210 0.95
4 24 1.9e-05 0.0014 18.9 3.1 1 23 216 238 216 238 0.97
5 24 4.4e-05 0.0031 17.8 4.7 1 23 244 266 244 266 0.99
6 24 8e-05 0.0057 16.9 5.7 1 23 272 294 272 294 0.97
7 24 3.9e-07 2.8e-05 24.2 4.3 1 23 300 322 300 322 0.98
8 24 1.4e-07 1e-05 25.6 2.4 1 23 328 350 328 350 0.97
9 24 8.2e-05 0.0058 16.9 6.7 1 23 356 378 356 378 0.97
10 24 1.9e-05 0.0013 18.9 8.4 1 23 384 406 384 406 0.97
11 24 6.4e-05 0.0046 17.2 5.1 1 23 412 434 412 434 0.97
12 24 6.6e-05 0.0047 17.2 8.7 1 23 440 462 440 462 0.97
13 24 6.4e-05 0.0046 17.2 5.1 1 23 468 490 468 490 0.97
14 24 0.00012 0.0088 16.3 9.4 1 23 496 518 496 518 0.96
15 24 8.2e-05 0.0058 16.9 6.7 1 23 524 546 524 546 0.97
16 24 0.00014 0.01 16.1 6.5 1 23 552 574 552 574 0.98
17 24 1.3e-05 0.00091 19.4 4.5 1 23 580 602 580 602 0.98
18 24 9.3e-06 0.00066 19.9 8.1 1 23 608 630 608 630 0.98
19 24 7.5e-06 0.00054 20.2 7.6 1 23 636 658 636 658 0.97
20 24 8.4e-07 6e-05 23.2 7.7 1 23 664 686 664 686 0.98
21 24 0.00026 0.019 15.3 9.5 1 23 692 715 692 715 0.95
22 24 9.4e-05 0.0066 16.7 0.9 1 23 721 743 721 743 0.98
23 24 0.001 0.073 13.5 3.4 1 23 753 775 753 775 0.97
24 24 1.2e-05 0.00083 19.6 1.6 1 23 781 804 781 804 0.96

Sequence Information

Coding Sequence
ATGCAGCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTTTCGGCACCGGTGGTGACCACTGGCGGTGGCACCACCATCACCTTGGGCGGAGGACCACCCCCAATAGCCAGTAAAATAACCGGCGGACACGGCGGCGTCAGCGATAATCATCATAATCATAAGGAGGACGGTAGCGGTAAACCGCCGCACGGCATTGAAATGTATAAAGTGAACATTGAGGATATATCACAGTTATTTACGTATCACGAAGTCTTTGGTAAAATCCATGGCGATGTGGTTAATCATGTGGCGGCGTTGCTAATGCCTAAAATGGAGGGCGGCATACATGGCGTCGATGGTCAGTCGAGTGTATCACTGGCGCCAGATGGGACGCCCATAGCGACTGGTACGCATGTATGCGATATTTGTGGCAAGATGTTCCAATTTCGTTATCAGCTGATTGTGCACCGTCGCTACCACAGCGAGCGTAAGCCGTTCATGTGTCAGGTGTGCGGTCAGGGTTTTACCACATCCCAGGATTTAACCCGTCATGGTAAAATTCATATTGGCGGTCCCATGTTCACCTGCATTGTCTGCTTCAATGTGTTCGCAAATAACACAAGCCTGGAGCGACATATGAAGCGACATTCGACAGATAAACCATTCGCCTGCACTATTTGCCAAAAGACTTTTGCACGCAAAGAGCATCTGGACAATCATTTTCGTTCCCATACGGGCGAAACGCCGTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTCAATCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTTACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACACCGCATCAGTGCGATGTCTGTGGCAAGAAATACACACGCAAGGAGCATCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGTGAGATCTGCGGCAAGAGCTTTAGCCGCAAGGAGCACTTCACCAATCACATACTCTGGCATACAGGTGAGACGCCACATCGGTGCGATTTTTGTTCAAAGACGTTTACGCGCAAGGAACACCTGTTGAATCACGTGCGCCAACACACTGGAGAGTCGCCACATCGCTGCACATACTGCCCGAAGACGTTTACGCGCAAGGAGCATCTTACGAATCACATACATCAGCACACGGGTGAGACGCCGCATCGGTGCGAGTTCTGTTCCAAGGCGTTTACACGCAAGGAGCATTTGGTTAATCACGTGCGCCAACATACGGGAGAGTCCCCACATCGTTGCACATACTGCTCGAAGACGTTTACCCGAAAGGAACATCTCACAAGCCACACATATACGCACACGGGTGAGACGCCGCATCGGTGCGAGTTCTGTTCCAAGGCGTTTACACGCAAGGAGCATTTGGTTAATCACGTGCGCCAACACACAGGAGAATCGCCACATCGTTGCACATACTGCTCGAAGACGTTTACCCGCAAGGAGCATCTCACGAATCACTTACATCTGCACACGGGCGAGACGCCACATCGGTGCGATTTCTGCTCCAAGACGTTTACGCGCAAGGAACATCTGTTGAATCACGTGCGTCAGCACACCGGGGAGTCGCCGCACCGCTGCTCGTATTGCATGAAGACGTTTACGCGCAAGGAGCATCTGGTGAATCATATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTACTGCACGAAAGCGTTCACTCGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACATACTGCACCAAGACGTTTACACGCAAGGAGCATTTGACGAATCATGTGCGTCAGCACACGGGCGATTCGCCGCATCGTTGCAGCTATTGCAAGAAGACCTTTACCCGCAAGGAGCATTTGACGAATCATGTTCGTCTCCATACAGGTGATTCGCCGCACAAATGTGAATACTGTCAGAAGACGTTTACGCGCAAGGAGCATCTCAATAATCATATGCGCCAACATTCGAGTGACAATCCCCATTGCTGCAATGTGTGCAACAAGCCGTTCACACGCAAGGAGCATCTGATCAATCATATGTCACGTTGCCACACCGGCGATCGTCCCTTCACCTGTGAGACATGTGGCAAATCGTTCCCCCTCAAAGGCAATCTGCTATTCCATCAGCGCAGCCACACCAAGGGACAGGAGTGTGAGCGTCCGTTTGCCTGTGAGAAGTGCCCCAAGAATTTCATATGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGTGAGAAACCACACGCGTGCACACTGTGCAGCAAGGCTTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCGTGCATCCGCATCCGCAAATACCGGCTGGTGTGCTGACCCAAGTCAAGCAGGAAGTGAAACCGATCATAACACCTACGCAGCAGCGCAGTTCCCTACTGCAGCTAAACGACGATGTCCTGGCCCTGATTGTGTCCCAGCTGAATGTGTATCAACAGTTCGAGCTGTCACAGCTCCACAGCCGCTTACGGAACATTGTCCAGTCATTGTGGCGGACGCGCGTGCGCAATGTAGCGCTGCAGGAGGAACAGCTACAGCGTGCCTCCTCGCGACAGTACCTGACGTTCATGTTACGCCTGGCACCGCATCTGGAGCGCCTGAGTTGCCATCAAATGGAAGTGCGCCGACTGCGACAGCTGAGTGATCAAACGTTGCGTGGCGTCACTAGCCTGGAATGGCTTGGAGGCGATCCTCCGCCGCGTGGACGTGGTGGCGGACGCTCCCGCTTTGTTGACGAGGATGTGCGCCTCTTGAAGCGTGTCTTTCCTGCGTTGCGCAAATTGAAACTGCGTAGTTGCCGCATTACTGGCAAATACCTTTGCGAACTGGAGCTACTCACCGATCTCTGCCTGGATGACTGTCAGTATCTGGAATCTCAGAACTTTCGCGACATCTTCCGCCAGCTGCGGCTGCGCAAGTTCGATATCATGGAGGATTGCGATGAGGTCAATTGCTGTGACCTGGCCGATGTGCAGCTGTGCCCCACGCTGGAGCACATCAAGATCGCCGACTATCATCTGTGCATGGAGTCGGACATTATGCAGCAGCTGCTGAGTCTGCCACGCCTGCAGAAACTATCGATATACTCCAAGAACTTCATCTTCGATGTGCTGGCTCGCGTGGCACGTCCTGGTCCTGGTGGCGCAGCGGTCAAGCAGATCGAAGGATTTCGCTTTGCCGGCATGCTACACGATTATGGACGTTTCTTTGATGAACTGAGTAATCTGCGCCAGCTACGTCGCCTGGAGGTGCACGCCCAGTCGGAGGAGGAGGGAGCACAATTGCAGTGTCTGAGTGATCAGATGCTCAGCCGCTTGGCGCCACAATTGCCGGAGCTGTGCGAGCTGCATTTGTGCGGCTATCAGCTGGAGAGTTCAGCCGGGCTGCTCCAATTTCTGAGCAACTGCCGCCAGCTGCGTCTGCTGAACATGAACAGATCCCGTTGCATTGGTGATGCCTTTGTCGCACGTTGCCTGGCACTGCTGATGAAGCAGAGCTGGCGCACGCAACCACTGGAGTTGTGGATCAGGCACAGTGACATCAGTGCCAGTGTAGCCCAGAATCCACGTTACCTGGTCAGCAACAAGTGGCTGCGAATCGATGCCCAACAAATGTCTCCACATCTGGGCAACCTGCCTGGCGTTCTTAAGTTTAGTTTTCTAAGATGA
Protein Sequence
MQHVSAASSAPSVVSAPVVTTGGGTTITLGGGPPPIASKITGGHGGVSDNHHNHKEDGSGKPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAALLMPKMEGGIHGVDGQSSVSLAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCTYCPKTFTRKEHLTNHIHQHTGETPHRCEFCSKAFTRKEHLVNHVRQHTGESPHRCTYCSKTFTRKEHLTSHTYTHTGETPHRCEFCSKAFTRKEHLVNHVRQHTGESPHRCTYCSKTFTRKEHLTNHLHLHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIITPTQQRSSLLQLNDDVLALIVSQLNVYQQFELSQLHSRLRNIVQSLWRTRVRNVALQEEQLQRASSRQYLTFMLRLAPHLERLSCHQMEVRRLRQLSDQTLRGVTSLEWLGGDPPPRGRGGGRSRFVDEDVRLLKRVFPALRKLKLRSCRITGKYLCELELLTDLCLDDCQYLESQNFRDIFRQLRLRKFDIMEDCDEVNCCDLADVQLCPTLEHIKIADYHLCMESDIMQQLLSLPRLQKLSIYSKNFIFDVLARVARPGPGGAAVKQIEGFRFAGMLHDYGRFFDELSNLRQLRRLEVHAQSEEEGAQLQCLSDQMLSRLAPQLPELCELHLCGYQLESSAGLLQFLSNCRQLRLLNMNRSRCIGDAFVARCLALLMKQSWRTQPLELWIRHSDISASVAQNPRYLVSNKWLRIDAQQMSPHLGNLPGVLKFSFLR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01552579;
90% Identity
iTF_01552579;
80% Identity
-