Zcap013430.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Zaprionus capensis
Gene Symbol
BTBD3
Assembly
GCA_018903675.1
Location
JAEIFN010000964.1:78927-81871[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.8e-23 4.4e-21 75.0 0.0 4 108 149 257 147 259 0.93
2 2 3.4 8.7e+02 0.0 0.0 76 108 257 289 255 291 0.83

Sequence Information

Coding Sequence
ATGTCACACTTAAACGGTGCATGGATAAATGTGGAGACGCTTAACAATGGCAACGGATTATTGCACTCGCCACCGCACAATCATCAACAACAACGTAGCACCACAGCTACTTCTCCCGGTGTAAGTTCTGGGAGTACTACGGATCAGAATATTCAAATAACACAGCCTATTAGCGCACCATCATCGCCGCTGGCATCGCCAAGCACATGCTCCACTACATTTTGTTTACCCTCGAGTTCTGCGGGTGCAGCAAGTCTGCAAGTTGCTTCACCTGCATCAGTGGCAAACGCAGCGATCACAATCCCAAATACCGGTAGTGCATCATATGTGTGTACATCTGGAAGCAATAGCAGCTACGCTGCTGTAGGCGCTTCTAATGCAATCGACACAGCTGATCCTAATTGGCAAGCAAGCAAAGCCACTGTGTTAGAGCGAAATGCGGCAATGTTCAACAACGAGCTTTTGTCTGACGTCAAGTTCATTGTGGGTAGCGATTTTGATTTTGATCCGATTCAAACTATACCCGCTCATAAGTACATACTCGCCACGGGCAGCTCCGTTTTTTATGCAATGTTCTACGGAGGATTGGCGGAGAATAAGCTGGAGATTAAGGTACCAGACGTGGAGCCCACAGCCTTCCTTACACTTCTAAGATATCTTTATTGCGATGAAATCAAATTGGAACCTGAACATATATTGGCTACCTTGTATGCGGCCAAGAAATATATTGTTCCACATTTGGCTCGGGCTTGCGTTAACTATCTGGAAGTTAAACTGACTGCAAAAAACGCCTGTCTTCTTCTCAGTCAATCACGCCTTTTTGAGGAGCCTGAACTGATGCAGCGTTGTTGGGAAGTCATTGACGCCCAGGCCGAAATGGCAGTTAAATCCGAGGATTTTGTAGATATTGACCTCAAAACCTTTGAATCAATACTGTCACGCGAAACCCTCAATTGTAAGGAGATACACCTCTTTGAGGCTGCCCTTAATTGGGCAATGAATGCATGTGAAAAGAAGAGCATAGATGAAACGTCTCAGAACAAGCGACGGGTCTTGGGACAAGCCTTGCATTTGATTCGCATTCCAACTATGACACTGGAGGAATTTGCTAATGGTGTAGCTCAAACTGGAATACTTACATCCCAAGAGACAATAGATATGTTTTTACATTTCACCGCAAAAGTAAAGCCGAACTTAAGTTTTCCCACACGACCGCGTGCCGGTCTTAAAACTCAAGTATGTCATCGCTTTCAATCATGCGCTTATCGCTCGAATCAGTGGCGATATCGAGGTCGTTGTGATTCCATACAGTTCTCAGTCGATCGACGAATTTTTATTGTTGGCTTCGGTTTATACGGTTCCTCAACGGGTGCGGCCAACTACAATGTTAAAATTGAACTTAAGCGCTTAGGCCGCACTTTGGCGGAAAATGACACGAAGTTTTTTTCAGATGGCTCTAGTAATACATTTCATGTGTTCTTTGATAATCCCATACAAATTGAACCAGAATGCTATTACACTGCTTCTGTTATACTTGATGGAAACGAGCTTAGCTTTTTTGGGCAAGAGGGCATGTCCGAAGTGCTTATGGGCAACGTTACATTCCAATTCCAATGCTCATCAGAAAGCACCAACGGAACTGGCGTACAGGGTGGACAAATACCAGAATTAATCTTTTATGGACCCACTACGGTAACGGCCTTAAGCTCGCCTGCAAACTCAATTTGCGCTACAACTATAGGATCGGCTCCTATAATCACAAATGGAGGTAATGTACAAGCTGGAACTATAAGTACCCTCGTAAACAATGCTTCCGATGAACCGACTCCAAACAGTGTGGCTGCTCTTAGTGATGCAAACAATACTTGA
Protein Sequence
MSHLNGAWINVETLNNGNGLLHSPPHNHQQQRSTTATSPGVSSGSTTDQNIQITQPISAPSSPLASPSTCSTTFCLPSSSAGAASLQVASPASVANAAITIPNTGSASYVCTSGSNSSYAAVGASNAIDTADPNWQASKATVLERNAAMFNNELLSDVKFIVGSDFDFDPIQTIPAHKYILATGSSVFYAMFYGGLAENKLEIKVPDVEPTAFLTLLRYLYCDEIKLEPEHILATLYAAKKYIVPHLARACVNYLEVKLTAKNACLLLSQSRLFEEPELMQRCWEVIDAQAEMAVKSEDFVDIDLKTFESILSRETLNCKEIHLFEAALNWAMNACEKKSIDETSQNKRRVLGQALHLIRIPTMTLEEFANGVAQTGILTSQETIDMFLHFTAKVKPNLSFPTRPRAGLKTQVCHRFQSCAYRSNQWRYRGRCDSIQFSVDRRIFIVGFGLYGSSTGAANYNVKIELKRLGRTLAENDTKFFSDGSSNTFHVFFDNPIQIEPECYYTASVILDGNELSFFGQEGMSEVLMGNVTFQFQCSSESTNGTGVQGGQIPELIFYGPTTVTALSSPANSICATTIGSAPIITNGGNVQAGTISTLVNNASDEPTPNSVAALSDANNT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01558383;
90% Identity
iTF_01554051; iTF_01548944; iTF_01552540; iTF_01553320; iTF_01558383; iTF_01559847; iTF_01551816; iTF_01555497; iTF_01557649; iTF_01554790; iTF_01559124; iTF_01556920; iTF_01550363;
80% Identity
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