Zafr014416.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Zaprionus africanus
Gene Symbol
ftz-f1
Assembly
GCA_018151435.1
Location
JAECXB010002310.1:20512913-20528469[+]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 1.7 9e+03 -4.5 0.6 60 76 24 40 6 54 0.43
2 3 1.3e-19 7.2e-16 58.4 0.8 1 79 214 291 214 309 0.74
3 3 9.3e-70 5e-66 223.6 0.8 157 408 376 620 347 622 0.90

Sequence Information

Coding Sequence
ATGTTATTAGAAATGGATCAGCAACAGGCGACTGTACAGTTTATATCGTCGCTCAACCTGTCGCCGTTTAGCATGCAGCTGGAGCAGCAGCAGCCAGCGAGCTACCAGGAGACAAACTCCTCGCACTCGCAGCAGAGTGGCAACGGCGGCACCTCAGTCAGTGGCAACGCTGGCCAATTGTTGAACGGCATTGGCAGCGGCGCTGGCAACTCTGCTGGCGGTGGCAGCTACATGTTGCTGCCACCTGGTGCCGGTGGCAATTCAGGCTCCGGTGCTGGTCACATGTCCAGCGGCGGTGGTGGAGGCTCTAGTGGAACTGGTGTTGGCGGCACCGGAGCTGGCGGTGGTGGCCATCACGGGGGCACAAGTGCAACCTCAGGTGGCAACGGCACCGGCGAAGCCATCGATTTCAAGCATCTCTTCGAGGAGTTGTGCCCCGTCTGCGGAGACAAAGTTAGCGGTTACCACTATGGCCTGCTCACCTGCGAGTCCTGCAAGGGCTTCTTCAAGCGCACCGTGCAGAACAAGAAGGTCTACACCTGCGTCGCCGAACGATCCTGTCACATCGATAAGACACAGCGCAAGCGTTGTCCCTACTGCCGATTCCAAAAGTGCCTCGAAGTGGGCATGAAACTGGAGGCTGTACGAGCGGATCGCATGCGAGGCGGTCGCAATAAGTTTGGCCCCATGTACAAACGGGATCGGGCGCGAAAGCTGCAGGTGATGCGACAGCGGCAATTGGCGCTTCAGGCGCTGCGCACCTCGATGGGGACGGACATAAAGACGACGCCCCTGTCCCCGGGCTATCAGCAAGCATATCCAAATATGAACATTAAGCAAGAAATTCAAATACCTCAGGTATCCTCACTCACACAGTCACCAGACTCGTCGCCCAGCCCCATTGCCATTGCCCTGGGTCAGGTGAATGCGAGCGGAGGCGGCGGAGGAGGAGGTGGCGGCAATAATGCTGGCGGCGGTGGCAGTGGAAACAACAGCGGCGATGGTCTGCAACGCAATGGAAACGGCGGCAATGGCAACAGCAACAGCAGCTGTCATGAAACCGGCACGGGATCTCTGCAGAACACAGCCGAATCGAAATTGTGCTTCGATTCTGGCACACATCCATCGAGCACAGCCGATGCGCTCATCGAGCCACTGAGGGTCTCACCAATGATACGCGAATTTGTGCAATCGATCGACGATCGGGAATGGCAGACGCAGCTGTTCGCTCTGCTGCAGAAGCAGACGTACAACCAGGTCGAAGTGGATCTCTTTGAGTTAATGTGCAAAGTGCTCGATCAGAATCTGTTCTCGCAGGTCGATTGGGCAAGAAACACCGTCTTCTTTAAGGATTTAAAGGTGGATGACCAAATGAAACTTCTACAGCACTCGTGGTCCGACATGCTTGTCTTGGATCATCTGCATCATCGCATACACAATGGGCTGCCCGATGAGACGCAGCTGAACAATGGGCAAGTGTTCAATCTGATGAGCCTGGGCCTTTTGGGAGTCCCACAACTTGGAGACTATTTCAATGAGCTGCAGAACAAGCTGCAGGATCTGAAGTTCGACATGGGCGACTATGTGTGCATGAAATTCCTAATACTGTTAAATCCAGATGTGCGAGGCATTGTGAACAAGAAGACCGTGCAGGAAGGACACGAGAGTGTGCAGGCAGCGCTGCTCGACTACACGCTCACCTGCTACCCCTCAGTAAATGATAAATTCAAGAGGCTATTGGACATTTTACCGGGAATTCACGCCATGGCCGCACGCGGCGAGGCGCATCTGTACTCAATGCACTGCGATGGTGGAGCGCCGACGCAGACGCTGCTGATGGAGATGCTGCACGCCAAGCGGAAGGTGTAA
Protein Sequence
MLLEMDQQQATVQFISSLNLSPFSMQLEQQQPASYQETNSSHSQQSGNGGTSVSGNAGQLLNGIGSGAGNSAGGGSYMLLPPGAGGNSGSGAGHMSSGGGGGSSGTGVGGTGAGGGGHHGGTSATSGGNGTGEAIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRTSMGTDIKTTPLSPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASGGGGGGGGGNNAGGGGSGNNSGDGLQRNGNGGNGNSNSSCHETGTGSLQNTAESKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQDLKFDMGDYVCMKFLILLNPDVRGIVNKKTVQEGHESVQAALLDYTLTCYPSVNDKFKRLLDILPGIHAMAARGEAHLYSMHCDGGAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01550327;
90% Identity
iTF_01548906;
80% Identity
iTF_01548906;