Yplu007500.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Yponomeuta plumbellus
Gene Symbol
ZEB2
Assembly
GCA_947310845.1
Location
OX371220.1:1121078-1132104[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 2.7e-06 0.00025 22.2 2.2 1 23 8 30 8 30 0.98
2 13 0.2 18 6.9 0.1 1 23 34 57 34 57 0.91
3 13 0.019 1.7 10.1 1.2 1 21 70 90 70 91 0.95
4 13 2.7e-05 0.0025 19.0 3.1 1 23 95 117 95 117 0.99
5 13 0.0036 0.33 12.3 0.8 1 20 126 145 126 147 0.94
6 13 0.13 12 7.4 1.5 1 20 159 178 159 182 0.87
7 13 0.00031 0.028 15.7 2.6 1 23 188 211 188 211 0.95
8 13 3.7e-07 3.4e-05 24.9 3.8 3 23 224 244 223 244 0.98
9 13 0.00069 0.064 14.6 0.2 1 23 250 273 250 273 0.96
10 13 0.0009 0.083 14.2 2.7 1 23 288 311 288 311 0.94
11 13 8.4e-05 0.0078 17.4 1.1 1 23 317 340 317 340 0.95
12 13 1.4e-05 0.0013 19.9 4.5 1 23 348 370 348 370 0.98
13 13 0.021 2 9.9 0.4 2 23 378 400 377 400 0.93

Sequence Information

Coding Sequence
ATGTTTCAGAGCGCGGGCAATTACCAATGCAACCTCTGCAAATATCGCTTCGACACACAATCCACCCTTCAGCAGCATATAGAGAAGCACTACCTGATGTACAAATGCCGCGTCTGCACGTACGAAAGCCGCAGTTGGAAACCAATGCAGGTCCACTGGGCAGAAGCGCACAAGAAAGTTGTTGAGAAGGCGCCGAAACTGAGTTCCTATCAGTGTAAGAGGTGTAAAGATAGTTTTGCAACTTTTCCACTCCTGCGCAAGCACAGACTTAAATGCTCGACGTACAAATGCGGCCAGTGCGAGAAGACGTTCAAATACCACTCGTCGTTGTATGAACACGCTCGGATACACAAGGAGGGGGCGCAGGACCAGATGTACTATTGTCAGGTGTGCGACACTCAGTTCAAGAGCGCGCGGTGGTACAAACAACACTTCAGCATCAGCTTGAAACATGTCTCTAGAGACGCTTTCAAACACGAGTGCCCGCACTGCCAGATGCGGTTCCACATCCCGCGGCGCTTGCGGGAGCATGTGGGCGCAGTGCACCTCAAACACGGGATCTACGCTTGCAGCCTTTGCCCGAAGACTTACATGACCAAGCTGCACTTGAAGAAACACCGAGCCAAGCTGCACAACATCGGCGATGTGGTGGTCGCCCGGGACAAGATCTGTGACCACTGCGGGAAGGCGTTCACGTCCAACCACCTCCTAAACAATCACATGCGCTCTCACACGGGCGAGAAGCCATACAAATGCCAGCTGTGCCCGGCCGCCTTCGCTCAGAACGGGACTCTGTACACTCACAACAAGAGTGTGCATCGGAAGAAGCTTAGTAAAGATGGCCATACGGATTCGCCTGCTTACCAGTGTGAGGAGTGCGGCAAGGAGTTCCCGACCAACTGCAAGCGGCAAGCCCACTACGAGTATTTCCATCTGAAACAGTCCAAGTTCACCTGCGAGGTTTGCAATAAGATTTTCATGTCATCGACATCTCTCAAGAACCACAACGCGACGCGACACGGCATGCTTTCCAGCAAGAGCTTCAACTGCGAGACTTGCGGAAAGAGATTCAATACATCGTCAGCGCGTTGCAACCATATGAAAACACACCTGGCAGACGGTAGCGGTCTGAAATGTCGTTCCTGCGACGCGGAGTTCAAAAACCCGGGCGCCCTCTACATGCATTTCAAACTCAAACACCTAAAGCTCAAACGTAGCGATAAAGTCAGTATTAAGAACCTGTGCAAGTCTGATAAAGAACTCATTGTTAACAGGGAGCCGCAGTGA
Protein Sequence
MFQSAGNYQCNLCKYRFDTQSTLQQHIEKHYLMYKCRVCTYESRSWKPMQVHWAEAHKKVVEKAPKLSSYQCKRCKDSFATFPLLRKHRLKCSTYKCGQCEKTFKYHSSLYEHARIHKEGAQDQMYYCQVCDTQFKSARWYKQHFSISLKHVSRDAFKHECPHCQMRFHIPRRLREHVGAVHLKHGIYACSLCPKTYMTKLHLKKHRAKLHNIGDVVVARDKICDHCGKAFTSNHLLNNHMRSHTGEKPYKCQLCPAAFAQNGTLYTHNKSVHRKKLSKDGHTDSPAYQCEECGKEFPTNCKRQAHYEYFHLKQSKFTCEVCNKIFMSSTSLKNHNATRHGMLSSKSFNCETCGKRFNTSSARCNHMKTHLADGSGLKCRSCDAEFKNPGALYMHFKLKHLKLKRSDKVSIKNLCKSDKELIVNREPQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01546867;
90% Identity
iTF_01546867;
80% Identity
-