Basic Information

Insect: Yponomeuta padella
Gene Symbol: Arhgef12
Assembly: GCA_947311075.1
Location: OX371254.1:11756337-11779662[+]

Transcription Factor Domain

TF Family: RFX
Domain: RFX domain
PFAM: PF02257
TF Group: Basic Domians group
Description: RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.0031 26 6.0 0.1 16 46 626 656 618 665 0.91

2 18 0.023 1.9e+02 3.2 0.1 19 46 656 683 655 685 0.93

3 18 0.0044 37 5.5 0.1 16 46 680 710 669 716 0.87

4 18 0.0034 29 5.8 0.1 15 46 730 761 714 770 0.84

5 18 0.0085 72 4.6 0.1 17 46 759 788 756 791 0.91

6 18 0.0062 52 5.0 0.1 16 46 785 815 778 818 0.89

7 18 0.0042 36 5.5 0.2 15 46 811 842 795 845 0.84

8 18 0.004 34 5.6 0.1 15 46 838 869 823 872 0.84

9 18 0.0053 45 5.2 0.2 16 46 866 896 858 905 0.88

10 18 0.0058 48 5.1 0.1 16 46 893 923 884 925 0.87

11 18 0.0037 31 5.7 0.1 15 46 919 950 904 956 0.85

12 18 0.0039 33 5.6 0.1 16 46 947 977 933 983 0.86

13 18 0.0052 44 5.3 0.2 16 46 974 1004 966 1013 0.88

14 18 0.005 42 5.3 0.1 16 46 1001 1031 991 1034 0.87

15 18 0.004 33 5.6 0.2 15 46 1027 1058 1013 1067 0.85

16 18 0.0052 44 5.3 0.2 16 46 1055 1085 1047 1093 0.88

17 18 0.03 2.5e+02 2.8 0.0 16 46 1082 1112 1070 1114 0.86

18 18 0.0047 40 5.4 0.1 15 46 1108 1139 1101 1148 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.0031	26	6.0	0.1	16	46	626	656	618	665	0.91
2	18	0.023	1.9e+02	3.2	0.1	19	46	656	683	655	685	0.93
3	18	0.0044	37	5.5	0.1	16	46	680	710	669	716	0.87
4	18	0.0034	29	5.8	0.1	15	46	730	761	714	770	0.84
5	18	0.0085	72	4.6	0.1	17	46	759	788	756	791	0.91
6	18	0.0062	52	5.0	0.1	16	46	785	815	778	818	0.89
7	18	0.0042	36	5.5	0.2	15	46	811	842	795	845	0.84
8	18	0.004	34	5.6	0.1	15	46	838	869	823	872	0.84
9	18	0.0053	45	5.2	0.2	16	46	866	896	858	905	0.88
10	18	0.0058	48	5.1	0.1	16	46	893	923	884	925	0.87
11	18	0.0037	31	5.7	0.1	15	46	919	950	904	956	0.85
12	18	0.0039	33	5.6	0.1	16	46	947	977	933	983	0.86
13	18	0.0052	44	5.3	0.2	16	46	974	1004	966	1013	0.88
14	18	0.005	42	5.3	0.1	16	46	1001	1031	991	1034	0.87
15	18	0.004	33	5.6	0.2	15	46	1027	1058	1013	1067	0.85
16	18	0.0052	44	5.3	0.2	16	46	1055	1085	1047	1093	0.88
17	18	0.03	2.5e+02	2.8	0.0	16	46	1082	1112	1070	1114	0.86
18	18	0.0047	40	5.4	0.1	15	46	1108	1139	1101	1148	0.89

Sequence Information

Coding Sequence: ATGTCGGGCGGCGCGGGCGGCGCAGCGGGCGGCGAGGAGCTGCTCACGGTGACCGTGCTGCGCGACGAGCATGGCTACGGGATGAAGGTTTCCGGCGACAACCCCGTGTACGTCCAGTCGGTGAAGGAGCACGGCGCGGCGTGGCGGGCCGGTCTGCGGGCTGGCGACCGCATACTCCGTGTGGACGGGGTGCCAGTTCATCGGCACACGCACCAGCAGGTCGTCCTCATGATCAGAGCCAACCCGTCCACCGTCCTGACGGTACACCAGAATGTGCAGCGGCTCAAGACGCCCATCACCGCGCCACTGCCTGTCAATTCGGAGAAGCAGAGACAGCTGGAGGTGACGAAGGCCAACACGTTCCGTCTCATGATGGAGCAAGAGCAGAAACACATCAACGAATTGCGCAACGAGCTATCGAAAGTTCCCGATCTGAGGAAGCAGCAGCAGCTTGAGTCGAGCGAGAAGCGTTTGGTCATGATGCAGAGGGAGATGGAGACACTCTCCGCCGCGCAGCCAGACACCCAGCCGTCGACGCCCAAATCGAACCGGTGGAAACCGGATAAGACCGGCTCGCCGCCGCCCAACACCGGTTTCCTCAGCGGCCTGCCTAGATCTCTTAGCAACCTCACCGGGCAGAGCTTACGCAACCTGCGAGCCAAGAAACAAGAGAACGTCCCTCCAAACCAACCGACTATAATCCGGCAAAACAGCGATGAGTCAAACCACAAGCGTCGACATAACAACACAGTGCCAATGGTCCCAACGACTTGTCTAGACAATGTCACTCCACCGCCGTTACCTCCGAGGACCAGGCCGATGAACCCTCTAGCAAAGCCTACGTACTACGGTCCGGGGTCACCGATGCACCAGTCGATGCCCGGTCCAACGAGAGAGGACCGCCGAGGGCTGAGGAGGTCGTCTCACTCGCTGGACGGAGAACTGGAGGGGCCGCAGCCCAATTCTATAGCGATGCAGATGAGCTATCCGCTTGTGAACGCGCCGCCGCCGCCTCTGCAGATTGACAACCGGCCGCCGATCCTCCACGCGCGGAGTCAGTCCTCGCCAGAACACCTCGACCATGGCCTCACAAGATCTTCTGAGGCGTGGCAGAGCCCCCCGCCCCCCGGCACTCCGCCGCCGCCCTACGCACATAATACCCAGCCGTGCGCCGACCCGCAGCGTGCTATTATATCGATGGAGGAAGATGACTCGCCCACTTCTGAGAACTCATCGCACTCGGGTCTGTTCAGCAACCTACGCGCCGTCCGGGATTCTAAGGCGCGCACCGCCGTACTGCTCAATTGGCTGCTAGGAGAGCGGAGGAGCGCGTGCGCTTGCCTGCTGCTGATCCTCACGGACGCGTACCGCGCGGCCGCCGCGCCCGCCGCCACGCTGCGCCGCTGGGCGTACGAGCTGCACTCCACCTTCCTCATGCCGCACGCCGTTTTACAACTGAGCGGCGTCGATGAGAACATGGCGAATGAGATCGAACACGTACTTTCCAATGAGTACGAGAAGCAGGAGCTCCTCCGCAACGTGTTCCGCAAGGCGCGGCAGCGCGCGAAGGACGAGCTGGCGCAGCAGCTCAGCGAGTTCCAGGTGAAGCGGCAGGTCGGCCTCGGCACCCTCTACGGCCCCGACGACCTGGTGCTGGGGAAGTGTGACGCGGATAAGGCGCAGGAGCAAATCGTGGTGGACCGCCTCATGTGCGGCCGCCTGAGTGATCTCTGCGCCGAGCCGGCGGCGGCGGGGGCGGTGGGGGCGGTGGGGGCGGCGGGGGCGGCGGGGGGAGAGCTGCTGGCTGCGTTGGTCGCGGCTGCGCACGCGTTGCAGTGTCGCGCGGCGGCGGTGGCGGCGGCGGCGGGCGGCGCACGCGCATGCTTCCTGCAGCGCGACAAGCTGTACAAGCAGCGGCTCAAGCTGCTGGCCAAGCAGCACGCGCAGCCCGTGAGTACCGCTTACTTCCTGCAGCGCGACAAGCTGTACAAGCAGCGGCTCAAGCTGCTGGCCAAGCAGCACGCGCAGCCCGTGAGTACCGCTTACTTCCTGCAGCGCGACAAGCTGTACAAGCAGCGGCTCAAGCTGCTGGCCAAGCAGCACGCGCAGCCCGTGAGTACCGCTTACTTCCTGCAGCGCGACAAGCAGCGGCTCAAGCTGCTGGCCAAGCAGCACGCGCAGCCCGTGAGTACCGCTTACTTCCTGCAGCGCGACAAGCTGTACAAGCAGCGGCTCAAGCTGCTGGCCAAGCAGCACGCGCAGCCCGTGAGTACCGCTTACTTCCTGCAGCGCGACAAGCTGTACAAGCAGCGGCTCAAGCTGCTGGCCAAGCAGCACGCGCAGCCCGTGAGTACCGCTTACTTCCTGCAGCGCGACAAGCTGTACAAGCAGCGGCTCAAGCTGCTGGCCAAGCAGCACGCGCAGCCCGTGAGTACCGCTTACTTCCTGCAGCGCGACAAGCTGTACAAGCAGCGGCTCAAGCTGCTGGCCAAGCAGCACGCGCAGCCCGTGAGTACCGCTTACTTCCTGCAGCGCGACAAGCTGTACAAGCAGCGGCTCAAGCTGCTGGCCAAGCAGCACGCGCAGCCCGTGAGTACCGCTTACTTCCTGCAGCGCGACAAGCTGTACAAGCAGCGGCTCAAGCTGCTGGCCAAGCAGCACGCGCAGCCCGTGAGTACCGCTTACTTCCTGCAGCGCGACAAGCTGTACAAGCAGCGGCTCAAGCTGCTGGCCAAGCAGCACGCGCAGCCCGTGAGTACCGCTTACTTCCTGCAGCGCGACAAGCTGTACAAGCAGCGGCTCAAGCTGCTGGCCAAGCAGCACGCGCAGCCCGTGAGTACCGCTTACTTCCTGCAGCGCGACAAGCTGTACAAGCAGCGGCTCAAGCTGCTGGCCAAGCAGCACGCGCAGCCCGTGAGTACCGCTTACTTCCTGCAGCGCGACAAGCTGTACAAGCAGCGGCTCAAGCTGCTGGCCAAGCAGCACGCGCAGCCCGTGAGTACCGCTTACTTCCTGCAGCGCGACAAGCTGTACAAGCAGCGGCTCAAGCTGCTGGCCAAGCAGCACGCGCAGCCCGTGAGTACCGCTTACTTCCTGCAGCGCGACAAGCTGTACAAGCAGCGGCTCAAGCTGCTGGCCAAGCAGCACGCGCAGCCCGTGAGTACCGCTTACTTCCTGCAGCGCGACAAGCTGTACAAGCAGCGGCTCAAGCTGCTGGCCAAGCAGCACGCGCAGCCCGTGAGTACCGCTTACTTCCTGCAGCGCGACAAGCTGTACAAGCAGCGGCTCAAGCTGCTGGCCAAGCAGCACGCGCTGCCCGTGAGTACCGCTTACTTCCTGCAGCGCGACAAGCTGTACAAGCAGCGGCTCAAGCTGCTGGCCAAGCAGCACGCGCAGCCCGTGAGTACCGCTTACTTCCTGCAGCGCGACAAGCTGTACAAGCAGCGGCTCAAGCTGCTGGCCAAGCAGCACGCGCTGCCCTTCGTAGTCCGCGGGCACCATCTGCAGCTGCGCGCGCTGACGTCACTGGCGCACTGCCACGCCTGCGACCTGCCGCTCGCCGGCCTCGCGCCGCAGGCCGCCGTCTGCGTCGGTACGTACCACATACACACTCGCCTCACTGTCACTCATACTCACTGTCACTCATACTCACTGCCGCTCGCCGGCCTCGCGCCGCAGGCCGCCGTCTGCGTCGGTACGTACCGCATACACACTCGCCTCACTGTCACTCATACTCACTGTCACTCATACTCACTGCCGCTCGCCGGCCTCGCGCCGCAGGCCGCCGTCTGCGTCGGTACGTACCGCATACACACTCGCCTCACTGTCACTCATACTCACTGTCACTCATACTCACTGCCGCTCGCCGGCCTCGCGCCGCAGGCCGCCGTCTGCGTCGGTACGTACCGCATACACACTCGCCTCACTGTCACTCATACTCACTGTCACTCATACTCACTGCCGCTCGCCGGCCTCGCGCCGCAGGCCGCCGTCTGCGTCGACTGCAAGCTGCACGTGCACCGCGCGTGCGCGCGCCACGTGGAGGAGCCGTGCTGCCTCGAGCCCAGCGACCAGCCGCACAAGCGCAGGTCGCGCTTCATGGAGCGGATACACGCGCAGGGTGAGTGTCGGCATCCGCCTGCCGCTGCCGGCGATCCTCTGGTATCCACTCGAGAACCCCATCGACTTTCGGTTCTTCCGCAGATATGA
Protein Sequence: MSGGAGGAAGGEELLTVTVLRDEHGYGMKVSGDNPVYVQSVKEHGAAWRAGLRAGDRILRVDGVPVHRHTHQQVVLMIRANPSTVLTVHQNVQRLKTPITAPLPVNSEKQRQLEVTKANTFRLMMEQEQKHINELRNELSKVPDLRKQQQLESSEKRLVMMQREMETLSAAQPDTQPSTPKSNRWKPDKTGSPPPNTGFLSGLPRSLSNLTGQSLRNLRAKKQENVPPNQPTIIRQNSDESNHKRRHNNTVPMVPTTCLDNVTPPPLPPRTRPMNPLAKPTYYGPGSPMHQSMPGPTREDRRGLRRSSHSLDGELEGPQPNSIAMQMSYPLVNAPPPPLQIDNRPPILHARSQSSPEHLDHGLTRSSEAWQSPPPPGTPPPPYAHNTQPCADPQRAIISMEEDDSPTSENSSHSGLFSNLRAVRDSKARTAVLLNWLLGERRSACACLLLILTDAYRAAAAPAATLRRWAYELHSTFLMPHAVLQLSGVDENMANEIEHVLSNEYEKQELLRNVFRKARQRAKDELAQQLSEFQVKRQVGLGTLYGPDDLVLGKCDADKAQEQIVVDRLMCGRLSDLCAEPAAAGAVGAVGAAGAAGGELLAALVAAAHALQCRAAAVAAAAGGARACFLQRDKLYKQRLKLLAKQHAQPVSTAYFLQRDKLYKQRLKLLAKQHAQPVSTAYFLQRDKLYKQRLKLLAKQHAQPVSTAYFLQRDKQRLKLLAKQHAQPVSTAYFLQRDKLYKQRLKLLAKQHAQPVSTAYFLQRDKLYKQRLKLLAKQHAQPVSTAYFLQRDKLYKQRLKLLAKQHAQPVSTAYFLQRDKLYKQRLKLLAKQHAQPVSTAYFLQRDKLYKQRLKLLAKQHAQPVSTAYFLQRDKLYKQRLKLLAKQHAQPVSTAYFLQRDKLYKQRLKLLAKQHAQPVSTAYFLQRDKLYKQRLKLLAKQHAQPVSTAYFLQRDKLYKQRLKLLAKQHAQPVSTAYFLQRDKLYKQRLKLLAKQHAQPVSTAYFLQRDKLYKQRLKLLAKQHAQPVSTAYFLQRDKLYKQRLKLLAKQHAQPVSTAYFLQRDKLYKQRLKLLAKQHAQPVSTAYFLQRDKLYKQRLKLLAKQHALPVSTAYFLQRDKLYKQRLKLLAKQHAQPVSTAYFLQRDKLYKQRLKLLAKQHALPFVVRGHHLQLRALTSLAHCHACDLPLAGLAPQAAVCVGTYHIHTRLTVTHTHCHSYSLPLAGLAPQAAVCVGTYRIHTRLTVTHTHCHSYSLPLAGLAPQAAVCVGTYRIHTRLTVTHTHCHSYSLPLAGLAPQAAVCVGTYRIHTRLTVTHTHCHSYSLPLAGLAPQAAVCVDCKLHVHRACARHVEEPCCLEPSDQPHKRRSRFMERIHAQGECRHPPAAAGDPLVSTREPHRLSVLPQI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -