Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 1 1.7e+03 0.8 0.0 23 44 87 108 84 112 0.86

2 7 0.00081 1.3 10.7 0.8 20 52 112 144 94 146 0.80

3 7 0.0064 10 7.9 0.1 21 53 141 173 137 174 0.89

4 7 6.3e-05 0.1 14.3 0.1 21 46 169 194 166 199 0.92

5 7 0.00012 0.2 13.4 0.2 21 44 227 250 220 255 0.91

6 7 0.17 2.7e+02 3.4 0.2 22 44 256 278 252 282 0.88

7 7 0.048 77 5.1 0.1 22 49 284 311 280 315 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	1	1.7e+03	0.8	0.0	23	44	87	108	84	112	0.86
2	7	0.00081	1.3	10.7	0.8	20	52	112	144	94	146	0.80
3	7	0.0064	10	7.9	0.1	21	53	141	173	137	174	0.89
4	7	6.3e-05	0.1	14.3	0.1	21	46	169	194	166	199	0.92
5	7	0.00012	0.2	13.4	0.2	21	44	227	250	220	255	0.91
6	7	0.17	2.7e+02	3.4	0.2	22	44	256	278	252	282	0.88
7	7	0.048	77	5.1	0.1	22	49	284	311	280	315	0.89

Coding Sequence: ATGTCTTTTTATGATCAAGTTAAATTTGAGATTGACGAGAAATATATAGTTGAAGAAGAATCTATAAAAGAGTCTTATGATTGTACAGAAAACAAAAAGAGTGACCAACATGCCGGTCTTTCCGGACGCTCGGAGATTTCATCCGATATAGGTgatgaaataaaaattgaaccGACGGAAACTAACGTGAACAAATTCAAATGTCCCAATTGTCCGAAAGTTTTCGCCACCAATTACGGGTTGATACATACGGGCAAGAAGCCGTTCGAATGCAAGATATGTAAAAAAGCGTTCCGTTGGCCCAACGGTTTAAAAACCCACATGTTCGTGCACACGGGCGAGAAGCCCCATAAATGTGGAATATGTAAACGAGCGTTTCGTCAGCCGCACGGCCTATGTCGTCATATGATGAGTCACAAGGTGGAGAGACCGCAcgtatgtgaaatatgtaaaatggCATTTCGCTTGCTCCAAACTTTAAAAAACCACATGTTATTGCACACTGGCGAGAAGCCCCAcgtatgtaaaatatgtaaaaaagggtACCGCTCTCGCCAAAATCTAAGGAAGCATTTTGAAATGCACACGGGGGGAAGAACTCATAAGTTCAAGTGCTGCCATTGTTCGAAAGCATTCTTCGCCAAGGGCGCGTTGACAAATCATTTGTCAGTACATGGGGGCGAGAAACCACATGCATGCGAGATATGTAAAAAGACGTTTCGTCTGGCACACTCTCTAAGAAGACACTTGATGTGCCACACCGGCGAGATGCCGTACAAGTGCGAATTATGCGAGAAAGCTTTCAGACAACAGGCGCATCTAACCCATCATATATTGATTCACACGGACGAGATGCCATTCAAATgcgaattttgtgaaaatgcGTTTCGTAAGGTTACGCAACTACGCTATCATATTATGGTTTGCCACGGGGACAAGAAATCTGATAAACGGGAAGAGGAAGAACCGCTTTCTGAGTCACAGCAAGTAAGTTGTACTGCTGGTATCGAGTGGTCGACGTAA
Protein Sequence: MSFYDQVKFEIDEKYIVEEESIKESYDCTENKKSDQHAGLSGRSEISSDIGDEIKIEPTETNVNKFKCPNCPKVFATNYGLIHTGKKPFECKICKKAFRWPNGLKTHMFVHTGEKPHKCGICKRAFRQPHGLCRHMMSHKVERPHVCEICKMAFRLLQTLKNHMLLHTGEKPHVCKICKKGYRSRQNLRKHFEMHTGGRTHKFKCCHCSKAFFAKGALTNHLSVHGGEKPHACEICKKTFRLAHSLRRHLMCHTGEMPYKCELCEKAFRQQAHLTHHILIHTDEMPFKCEFCENAFRKVTQLRYHIMVCHGDKKSDKREEEEPLSESQQVSCTAGIEWST

Sequence clustering based on sequence similarity using MMseqs2