Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.38 6.1e+02 2.2 0.0 11 44 12 43 7 47 0.64

2 9 0.0021 3.5 9.4 0.7 21 44 48 71 45 75 0.92

3 9 5.1e-08 8.1e-05 24.2 0.2 21 51 76 106 72 107 0.88

4 9 0.021 34 6.2 0.0 21 52 104 135 102 137 0.86

5 9 0.6 9.6e+02 1.6 0.0 22 46 133 157 128 163 0.80

6 9 0.31 5e+02 2.5 0.0 21 44 160 183 152 187 0.85

7 9 0.003 4.9 8.9 1.4 21 48 188 214 185 216 0.92

8 9 0.2 3.2e+02 3.1 0.9 22 48 217 242 213 244 0.86

9 9 0.0043 6.9 8.4 0.3 18 43 241 266 240 268 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.38	6.1e+02	2.2	0.0	11	44	12	43	7	47	0.64
2	9	0.0021	3.5	9.4	0.7	21	44	48	71	45	75	0.92
3	9	5.1e-08	8.1e-05	24.2	0.2	21	51	76	106	72	107	0.88
4	9	0.021	34	6.2	0.0	21	52	104	135	102	137	0.86
5	9	0.6	9.6e+02	1.6	0.0	22	46	133	157	128	163	0.80
6	9	0.31	5e+02	2.5	0.0	21	44	160	183	152	187	0.85
7	9	0.003	4.9	8.9	1.4	21	48	188	214	185	216	0.92
8	9	0.2	3.2e+02	3.1	0.9	22	48	217	242	213	244	0.86
9	9	0.0043	6.9	8.4	0.3	18	43	241	266	240	268	0.90

Coding Sequence: ATGTTTAGTaatgaaataattaatgaaccggaggaaactgaaaaagaaaaaggaaaagaCCGAAATAAATTCGTATGTCCCGAATGTCCAAAAGTCTACACCACTGTCAGAGGGTTCAAATACCATTTATTGATGCATACTGGTGAAAAACCGAACAAATGCGAGATATGTAATAAAGCGTTCTGTCAGCCGCATATTTTAAGACGTCATATGATGTGTCACTCGGACGAGAAGCCCCATACCTGCGAAATCTGCAAAAAAGTCTTCCGTTGCTCCAGAAATCTAAAGACTCACATGATGTTGCATACAGGCGAGAAGCCCTACAAATGCGAAGTATGCGAAAAGGGGTTCCGTCAGGCCGTGCATCTAACTAACCATATGGGGCGCCATACAGTCGGGAAGCCGCATAAATGTGACATTTGCGAAAGAGGCTTCCTCTCCTCCCAATATCTAAAGGACCACATGAAGTGTCACACGGATGAGAAGCCCTTCAAGTGCGAGATTTGCGATATACAGTTCCGCGCCTTAAAATATATAAAGAATCacatgatgtgccacacaggtgaGAGACCGCACAAGtgcgaaatatgtaaaaaagcgttCCGTCGAGCGGCGCATCTGGAGAGACACATGCTGCGTCACGGACGCGAGAACTCCAACGAATGCGAGATTTGCAAAAGACTCTTCTGTTACGAACAAACTTTAAAGCGTCACATGTTGCGCCACACCGACGAGAAGCCTTACGAATGCAAAATTTGTAAAAAGATGTTCCGTCACTCGCAAACTCTAAAGTGTCATTCGTGTCGTCCGGACAAGCTTTAA
Protein Sequence: MFSNEIINEPEETEKEKGKDRNKFVCPECPKVYTTVRGFKYHLLMHTGEKPNKCEICNKAFCQPHILRRHMMCHSDEKPHTCEICKKVFRCSRNLKTHMMLHTGEKPYKCEVCEKGFRQAVHLTNHMGRHTVGKPHKCDICERGFLSSQYLKDHMKCHTDEKPFKCEICDIQFRALKYIKNHMMCHTGERPHKCEICKKAFRRAAHLERHMLRHGRENSNECEICKRLFCYEQTLKRHMLRHTDEKPYECKICKKMFRHSQTLKCHSCRPDKL

Sequence clustering based on sequence similarity using MMseqs2