Basic Information

Gene Symbol
-
Assembly
GCA_963966045.2
Location
OZ014502.1:26714052-26715455[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 5.6e-05 0.0045 18.9 0.2 1 23 72 95 72 95 0.95
2 13 0.73 59 5.9 7.5 1 21 101 121 101 123 0.94
3 13 7.2e-05 0.0058 18.6 3.6 1 21 129 149 129 151 0.95
4 13 0.0022 0.17 13.9 7.1 1 21 157 177 157 179 0.95
5 13 0.002 0.16 14.0 6.5 1 20 185 204 185 207 0.95
6 13 1.6e-06 0.00013 23.7 6.7 1 23 222 244 222 244 0.98
7 13 1.4e-05 0.0012 20.7 2.5 1 23 250 272 250 272 0.98
8 13 0.00038 0.031 16.3 8.1 1 23 278 300 278 300 0.98
9 13 6.1e-05 0.0049 18.8 5.4 1 21 306 326 306 328 0.95
10 13 2.8e-07 2.2e-05 26.2 3.6 1 23 334 356 334 356 0.98
11 13 0.39 32 6.8 5.0 1 20 362 381 362 384 0.95
12 13 2.6e-05 0.0021 19.9 3.6 1 23 390 412 390 412 0.97
13 13 0.00063 0.051 15.6 1.9 2 23 419 440 418 440 0.97

Sequence Information

Coding Sequence
ATGTCTCTTTCTGAACGAAGCGAAGCATCAGTTTTTTATGTAGAGGACAAAAAGATAACCGAGTTCCGTTCAGAAATGTCAGTTTGCGATCCAGTTAAAGTGGAATTAAAAAATGATTTAAGCGACATAGATAtagaagaaaaatttattgtagacGAAGGAGGGTCGGAATTGAAAAATGAACCAGAGGAAACTGTTAAACAAAAAAGGAAATTTAAGTGTTCCGAGTGCCCGAAAGTGTATGTCAGCAAAGGTGCgttgaaattgcattttttgtcGATACACGTGGGCGATAAAATGCACAAGTGCGAGATATGTAGTAAAACGTTCCATTGGCCGCATGTCCTGAGACGTCATATGAAGTGTCACGCGAATAGGAAACCCCACAAGTGTGTAATTTGTGAAAAAGTGTTTCGTGATTCCGAAAATCTAAAGTACCACATGATGTGTCACACGGGGgagaagcctcacaaatgtgactTATGCGATAAGTTGTTTCGGCACTCTCAAAACCTGAAGACTCACATgctgtgccacacaggcgagaaacctcacaaatgcgaaatttgtaaaaaagaGTTCCGTTACTCCCGAACTCTCAAGCGTCACTTGACGTGTCACGATGATAAGAAGCGTCAAGTGACACGTCACGATGAGAAGCGCCATAAGTGCGAAACGtgtaaaaaagcgttctctcatcCACAGAATCTGAAGAGGCATATGAAGCGTCACACGGcggagaagccccacaaatgtgaagttTGCAAAAAAGGCTTCCCTTATTTACAAAGCCTGAAGCGTCACATGATGTCTCACACGAACGAGTGGCCCCATAAATGCGAAATTTGTAACAAAGGCTTTTGTCACCTCCAGAATCTGAAGCACCACGTGATGGTCCACGCGGACCAGAGATCCCACAAGTGCGACGTCTGCAAAAAAGTGTTCCGTCAGCCCGCGCATCTAACCGATCAcatgaagtgccacacagacgacaagcctcacaaatgcgaaatttgtaACAAAATGTTTAGTCGTTCCCGAAATTTAAAAACGCACATGATCAGTCACACCgacgagaagccccacaaatgtgaaatatgcgaTAGCACATTCGGTTGCTCCTCGAACCTAATCGTTCACATGTTTTGTCACACGGGAGAGAAGCCGCATAGATGTGACATTTGTAAGAAAGATTTCCGTTACTCCCAAGACCTGAAAAGACATTTGTTGTCCCACACCAACGAGATACCCAACCAATGCCACATTTGCAAGAACGGGTTCAGTTCCAAACAATATTTAAAGATTCATTTAATGGGCCATgcaaaagaaaaacaagattTGTAA
Protein Sequence
MSLSERSEASVFYVEDKKITEFRSEMSVCDPVKVELKNDLSDIDIEEKFIVDEGGSELKNEPEETVKQKRKFKCSECPKVYVSKGALKLHFLSIHVGDKMHKCEICSKTFHWPHVLRRHMKCHANRKPHKCVICEKVFRDSENLKYHMMCHTGEKPHKCDLCDKLFRHSQNLKTHMLCHTGEKPHKCEICKKEFRYSRTLKRHLTCHDDKKRQVTRHDEKRHKCETCKKAFSHPQNLKRHMKRHTAEKPHKCEVCKKGFPYLQSLKRHMMSHTNEWPHKCEICNKGFCHLQNLKHHVMVHADQRSHKCDVCKKVFRQPAHLTDHMKCHTDDKPHKCEICNKMFSRSRNLKTHMISHTDEKPHKCEICDSTFGCSSNLIVHMFCHTGEKPHRCDICKKDFRYSQDLKRHLLSHTNEIPNQCHICKNGFSSKQYLKIHLMGHAKEKQDL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01537482;
90% Identity
iTF_01537482;
80% Identity
iTF_01537482;