Basic Information

Gene Symbol
-
Assembly
GCA_963966045.2
Location
OZ014503.1:24287558-24289413[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 7.2e-06 0.00058 21.7 0.4 1 23 76 98 76 98 0.95
2 16 2.8e-05 0.0023 19.8 1.8 1 23 104 126 104 126 0.98
3 16 0.00015 0.012 17.6 7.3 1 21 132 152 132 154 0.93
4 16 9.4e-06 0.00076 21.3 0.1 1 23 160 182 160 182 0.99
5 16 2.5e-06 0.0002 23.1 2.8 1 23 188 210 188 210 0.98
6 16 9.1e-06 0.00073 21.4 2.1 1 21 216 236 216 238 0.96
7 16 0.00015 0.012 17.6 4.7 1 23 244 266 244 266 0.97
8 16 0.00031 0.025 16.6 2.2 1 21 272 292 272 294 0.95
9 16 2.8e-06 0.00023 23.0 1.6 1 23 300 322 300 322 0.96
10 16 0.0066 0.54 12.4 6.9 1 21 328 348 328 350 0.95
11 16 1.9e-05 0.0016 20.3 3.5 1 21 356 376 356 378 0.93
12 16 1e-05 0.0008 21.3 1.9 1 21 384 404 384 406 0.95
13 16 4.2e-06 0.00034 22.4 2.3 1 23 412 434 412 434 0.97
14 16 3.7e-05 0.003 19.5 1.3 1 20 440 459 440 462 0.95
15 16 1.4e-06 0.00011 24.0 6.8 1 23 468 490 468 490 0.98
16 16 0.0024 0.19 13.8 1.2 1 23 509 531 509 532 0.95

Sequence Information

Coding Sequence
ATGTCCTTTTGCGATCCGATTAAAACTGAATTAGAAACAGAATGGGTTGAAATAAAGATGGAAGAAAAATTTGTAATTGAGGAACAAGAGTCGATGAAAGAATCGGTTGTTACGTCAGATTTTTGTATAGAGGACAAAAAGGCGGTGATTATTCTGAATGCAAATaacgatgaaataaaaaatgaatctAATCTTCAAAGAAAAACTGATAATAGCACAAAGAAATTCAGATGTCCCGATTGTCCGAAAGTCTTTGTCTACAACTCCTCGTTGAAATACCATGCAACATTACATACAgGAAAGAGACCATACGAATGTGATCAATGTGAGAAAGCGTTCAATCATCCCAACACTTTAAAGAACCACAAGATTACCCACACTGACAAGAGACCGCACGCATGCTTAGTATGTAATAAAACGTTCCGTCAGAAATCACATCTGAATACTCATATGAGGTGCCATACGGATGAGAGACCGTACAAATGTGGCATATGTGATGAAGCATTCCGTCAACCCAACCCTTTAAAGATGCATATGCTGAGCCACTCGGATGAGAGGCCCTACATCTGCGAAGTGTGTAACAAAACGTTCCATCAGCCCAGCTTTTTAAAGAAGCACATGATGAGCCACACAGATGAGAGACCCTACAAATGTGGAATATGTGATAAAGCATTCCGCTATAAATGGAATCTAAATGATCATATGATGTGCCACACGGAAGAGAGGCCTCATACCTGCGAAATATGTAACAAAGCTTTCCATCAACTCAGCTCTCTGACGAAGCATAAGATCAGGCACACGGGTGACAGGCCCTACACCTGTGAAGTATGCAACAAAGCATACCGTTATAAATGGAATCTAAGTGATCATATGTTGTGCCACACGGATGTGAAGCTCCACGCCTGTGAAATATGTAACAAGGCATTCTATCAGCTCAGCTATCTAAAGAAGCACATGATAAGCCATACGGATGAGAGACCccataaatgtgaaatatgtaacaaAGCATTCCACTATCAGTTTACTCTAAATAATCATATGATGTGCCATACGGATGAGGGGCACCACATTtgtgaaatatgtaataaaGTGTTTAACCAGTCCAGCTCGTTAAAGAAGCATATTATGTGCCACACAGATGAGAGACCCTACAGTTGCGAAATATGTGACAAAGCATTCCGTTACAAATGGAATCTAAATGAGCATATGATGTGCCACACGGGTGAGAAGCCCCACACCTGCGACATTTGTAACAAAGCTTTTTATCAACCCAGCTCTCTGAAGAAGCACAAGATTAGTCACACAGACAATAGGCCCTACGTGTGTGAAGTATGTAACGCGGCATTCCGTTATAAATCAAATCTAAATAAACATATAATATGTCACTCGGATGAGAGAAACCACACGTGTGAAACATGTAAAAAGTCGTTTCGTTATAAAACGAATCTGAATCGCCACATGAGGCGCCACAAGTCCTCGAATCTAAACAATCAAATGACACACCAGAGAAGCGGCAAAAGATCATATCGCTGCCAAATATGCGCGATGGTTTTTAATCGGAAAGGTGAACTCGATGAACATTTTAATAATCATCATAAAGGTAATACGGGCACAAAGCCAGAGAAGTTAAAATTCGTTGGATTAGAAGAAGGAATTAAAGCTGAAGAAAGTCAAATTGATGAAGTTGTGAAGAAAGAAGACACATTTTGA
Protein Sequence
MSFCDPIKTELETEWVEIKMEEKFVIEEQESMKESVVTSDFCIEDKKAVIILNANNDEIKNESNLQRKTDNSTKKFRCPDCPKVFVYNSSLKYHATLHTGKRPYECDQCEKAFNHPNTLKNHKITHTDKRPHACLVCNKTFRQKSHLNTHMRCHTDERPYKCGICDEAFRQPNPLKMHMLSHSDERPYICEVCNKTFHQPSFLKKHMMSHTDERPYKCGICDKAFRYKWNLNDHMMCHTEERPHTCEICNKAFHQLSSLTKHKIRHTGDRPYTCEVCNKAYRYKWNLSDHMLCHTDVKLHACEICNKAFYQLSYLKKHMISHTDERPHKCEICNKAFHYQFTLNNHMMCHTDEGHHICEICNKVFNQSSSLKKHIMCHTDERPYSCEICDKAFRYKWNLNEHMMCHTGEKPHTCDICNKAFYQPSSLKKHKISHTDNRPYVCEVCNAAFRYKSNLNKHIICHSDERNHTCETCKKSFRYKTNLNRHMRRHKSSNLNNQMTHQRSGKRSYRCQICAMVFNRKGELDEHFNNHHKGNTGTKPEKLKFVGLEEGIKAEESQIDEVVKKEDTF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01537497;
90% Identity
iTF_01537497;
80% Identity
iTF_01537497;