Xxan060111.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Xestia xanthographa
Gene Symbol
egg
Assembly
GCA_905147715.1
Location
LR990667.1:9375261-9413426[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.2 9.9e+03 -1.8 0.1 28 38 322 338 292 340 0.65
2 2 2.1e-13 1.7e-09 39.1 0.0 4 73 370 432 367 436 0.88

Sequence Information

Coding Sequence
ATGAAACATCTTCCAACCCGGCTGGTCACCGTGGAAGATTATGACCAAAACCCTCCAAAAGAAACCACACAAACAGagaacagaaacaataaacgaTCAACTCAATTAAAAATTGCAACATATAACGTCCGGACCTTATCGTCATACGAACGCTTACTCGAACTAGAAGAAGCAATAAAGGAAATTAATTACGACATTATAGGTATCTCAGAAGTGAGACGACTTGGTAACAAGATAGAGGAATACGAGAACTTAATACTCTGCCACATAGGTTGTACACCAGGTACGCGTCTCATAGCTCTGTTCAAGGATTCGAATAAGCGTGAGTCTTACTACTCAGGCGTAGTCGCTGAAATACCGAATCCGGTCAATAATTATAGATACCTAGTATTCTTCGACGATGGCTACGCTCAATACGTACAGCATCAGTACACCCGCCTAGTTTGCGAGAGCTCCAATCATGTATGGGATGAAGTGCATCCATTCTCGCGGGAGTTCGTACACAATTACCTGAAAGCGTACCCTGAGAGACCCATGGTCAGACTGCACACGGGGCAGCATCTGAAGACTGAGTGGAACGGAAAATGGTGGCCATCCCGAGTAACCCGGGTAGACGCATCATTAGCTCAGGTGATGTTCGTGGAGGACGGACGGCGCGAGTGGATCTACCGTGGTTCAACACGACTCGCACCCTTGTACCTGGAGCTACAAGCCGCGGAAAGACATCGGCCCCGACCCTTACCCCGGGGCAAGGCGCCACCTAGGCTAAATATGCCATACGTGGAGTACATTCGGTCAGATGAGCAGGAGTCCAGCAAGCCAACAGACGCACAGGTGCAGGCTCAACAGGAAATGCAAAAACAACAGCTGCAGCGAGATGAGGAGATTCGTCGCCAACGCGCCGTGGCCAAGAAGTCCACATCAGCGCCTCCTCAAGTGTACCCGCCGGCGCATCCGGTGCCGCCGCCCGTTAACACAGATCCCGTCACCAGCAGAGTTGTGTACTACACACCGAAGAATGCAGTCAGGCCATTGAAGATGGTCCCACATAGATGCACTCCTAAATGCAAGAGAGGCGACGTGCTTTCATTAAAGGAGTTGAGGACTTACAACCCGCTGGCCAAACCACTGCTTAGCGGATGGGAAAGACAAATAGTCCGCTTCAAGGGCCACAAGGACGTAATGTACCGCGCGCCGTGCGGGCGACGCATACGCAACATGCGCGAGCTACATCACTACTTACGTTCTATAGACAGTGACCTGCCCGTAGATCTCTTCGACTTCCACTACTCCACGCACTGTCTGGCGGAGTTCGTGTTGAACAAGTGTCTTGTGGGGAAAAAGGACCTTTCCCACGGCAAAGAGAACGTCCCGGTGCCGTGCGTGAACTACTACGACGACTCGCTGCCGGAGTTCTGTTCGTACAACACCGAGCGCACtcccaccgccggggtgccgcTCAACTTGGAGCCCGAGTTCCTGTGCGGCTGCGACTGTACTGACGATTGTCAGGATAAATCAAAATGCGCTTGCTGGAAGATGACTCTAGAGGGCGCTCGGACTATCGGCCTGGTCGGGCCAAATGTGGGTTATGTCTACAAACGACTGCCCGAACCGTTACCTTCTGGAATATATGAGTGTAATTCTAGATGTAAATGCAAGCATACGTGTCTAAATCGCGTCGCACAGCATCCACTACAATTGAAGTTGCAGGTATTCAAAACTCCAAACCGCGGTTGGGGTATCCGCGCACTGAACGACGTTCCCAAAGGATCCTTCCTCTGCGTGTACGCAGGTAACCTGCTCACAGATGCTACGGCTAACTTGGACGGGTTGAATGAAGGCGACGAATATTTAGCAGAACTGGATTACATAGAAGTTGTCGAACAAATGAAGGAAGGATATGAAGAAGACATTCCTGAGGCCCATAAGAAATCAGACAAGAAAGAATCAGGTAAGGATGGTGAAGACAGTGATGAAGAGCAATCGTCATCATCTGAAGATGAGGACACCGCCTCCAAGACTGACAAGGAAGATTACGACTTTAGACCTGGGAGCATTGGACTGGGGGCTGGCGTTGCGGAGTTCAACAAACGCCTCCGTAAACGCGAGAAATCAAAGAAAGATAAAGCAAATGCGGCGGCTGACGATAAAGATGTAACTAAAGATACAACAAAAGATAATAAAGAACAAAAGGAAGAAATGAAGAATGCTGAAGATGATTGTATTACCATTAGTGATGATGAAGAAGtACGAGAACCTTCAAGATTCATGGCACAAACAAAAATGGGAGCTAACGAGTATATATCTAAATACAAATCTGTTCGCACACTTTTCGGTAAGGACGAGGCGTGCTATATCATGGACGCTAAGGTTCAAGGCAACATTGGCAGATATCTCAATCACTCCTGCTGCCCCAACGTATTCGTACAGAACGTCTTCGTGGACACCCACGACCCTCGTTTCCCCTGGGTGGCGTTCTTCGCGCTATCTCACATTAAGGCGGGCACAGAGCTCACGTGGAACTACAACTATGACGTGGGTTCGGTTCCCGGCAAGATACTGTACTGTTACTGCGGCGCCGTCAATTGTAGGGGGCGACTTTTGTAA
Protein Sequence
MKHLPTRLVTVEDYDQNPPKETTQTENRNNKRSTQLKIATYNVRTLSSYERLLELEEAIKEINYDIIGISEVRRLGNKIEEYENLILCHIGCTPGTRLIALFKDSNKRESYYSGVVAEIPNPVNNYRYLVFFDDGYAQYVQHQYTRLVCESSNHVWDEVHPFSREFVHNYLKAYPERPMVRLHTGQHLKTEWNGKWWPSRVTRVDASLAQVMFVEDGRREWIYRGSTRLAPLYLELQAAERHRPRPLPRGKAPPRLNMPYVEYIRSDEQESSKPTDAQVQAQQEMQKQQLQRDEEIRRQRAVAKKSTSAPPQVYPPAHPVPPPVNTDPVTSRVVYYTPKNAVRPLKMVPHRCTPKCKRGDVLSLKELRTYNPLAKPLLSGWERQIVRFKGHKDVMYRAPCGRRIRNMRELHHYLRSIDSDLPVDLFDFHYSTHCLAEFVLNKCLVGKKDLSHGKENVPVPCVNYYDDSLPEFCSYNTERTPTAGVPLNLEPEFLCGCDCTDDCQDKSKCACWKMTLEGARTIGLVGPNVGYVYKRLPEPLPSGIYECNSRCKCKHTCLNRVAQHPLQLKLQVFKTPNRGWGIRALNDVPKGSFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGYEEDIPEAHKKSDKKESGKDGEDSDEEQSSSSEDEDTASKTDKEDYDFRPGSIGLGAGVAEFNKRLRKREKSKKDKANAAADDKDVTKDTTKDNKEQKEEMKNAEDDCITISDDEEVREPSRFMAQTKMGANEYISKYKSVRTLFGKDEACYIMDAKVQGNIGRYLNHSCCPNVFVQNVFVDTHDPRFPWVAFFALSHIKAGTELTWNYNYDVGSVPGKILYCYCGAVNCRGRLL*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01030263;
90% Identity
-
80% Identity
-