Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 6.2 4.7e+03 -1.7 0.0 24 43 106 125 99 133 0.73

2 7 0.0028 2.2 9.0 0.1 23 52 133 162 123 164 0.84

3 7 3.8 2.9e+03 -1.0 0.1 22 38 160 176 156 187 0.74

4 7 0.24 1.8e+02 2.8 0.1 24 47 190 213 179 219 0.88

5 7 2.6 2e+03 -0.5 0.0 22 44 216 238 211 242 0.82

6 7 4e-05 0.031 14.9 0.0 21 45 243 267 240 274 0.86

7 7 0.021 16 6.2 0.4 23 48 273 297 270 301 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	6.2	4.7e+03	-1.7	0.0	24	43	106	125	99	133	0.73
2	7	0.0028	2.2	9.0	0.1	23	52	133	162	123	164	0.84
3	7	3.8	2.9e+03	-1.0	0.1	22	38	160	176	156	187	0.74
4	7	0.24	1.8e+02	2.8	0.1	24	47	190	213	179	219	0.88
5	7	2.6	2e+03	-0.5	0.0	22	44	216	238	211	242	0.82
6	7	4e-05	0.031	14.9	0.0	21	45	243	267	240	274	0.86
7	7	0.021	16	6.2	0.4	23	48	273	297	270	301	0.84

Coding Sequence: ATGACAAGCGAACCACCTTACATCCGAGAGGGAATAATAGAAGAAAAAATGATAATCGAACCcgaaatttcatttattaaaattgaatgcGGTGCATTTGACGAGAATGACGATTTGTACGACATGGGAACGGTGAAAAACGAAGAGGACGATGGTATAAATAGAGTCCCTGACTCTCGAGAACAAAGTAGAATCAAACaagatactaataaaaaacaaaatacaaacaaacaaatgaacagtgTCGGTGATGGAAGAACTATAGTTGACAAGAGAAGAATTAGTGTTAAAAATGGAAGTAGTACCGATAAGAAAAACATCAtgtgtgatatttgtaaaaaaaaatttagtaatatGAACGGTCTTCGATCGCACAACCTAATCCATATGAATATGAAACCATTTAAATGCAATGTTTGCGATAAATCGTTCAGACAATCGGGCATTTTAAAAAGACATAAATTAATTCATTCCGGTGATAAACCGCACGTTTGCGATGTCTGTAAGAGATGCTTCCGATTACCGAGTATACTAAATTCGCATCGGCTGCTTCACACCGACGTGACACCTTACCAGTGCGAAGTCTGCCAGAAATTTTTCACTCAGCAAACGGCACTAAAGCTTCACTTAAAAATGCACAGCGGTGACAGACCGCATAACTGCGAAGTCTGCGGTAAAAGTTTTAGGTTAATGGGCGACTTAAAATCACATTTCTTAATACATACAGGGGAGAAACCGTTTAAATGTGATATTTGCGGTATGGAATTTAGACAGTCAAGTAATCTAAGAAGCCATCAGATGATTCATACGGGATTAAAACCGTATCGGTGCGATCTCTGTCATAAGACTTACGGACGGTCGTCGAATTTGAAAAGGCATCGATTGAGTCACATACGTAAAGGAATTTAA
Protein Sequence: MTSEPPYIREGIIEEKMIIEPEISFIKIECGAFDENDDLYDMGTVKNEEDDGINRVPDSREQSRIKQDTNKKQNTNKQMNSVGDGRTIVDKRRISVKNGSSTDKKNIMCDICKKKFSNMNGLRSHNLIHMNMKPFKCNVCDKSFRQSGILKRHKLIHSGDKPHVCDVCKRCFRLPSILNSHRLLHTDVTPYQCEVCQKFFTQQTALKLHLKMHSGDRPHNCEVCGKSFRLMGDLKSHFLIHTGEKPFKCDICGMEFRQSSNLRSHQMIHTGLKPYRCDLCHKTYGRSSNLKRHRLSHIRKGI

Sequence clustering based on sequence similarity using MMseqs2