Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.22 1.7e+02 3.0 0.1 21 43 144 166 136 172 0.88

2 7 0.069 53 4.6 0.0 21 43 172 194 167 200 0.90

3 7 0.0086 6.6 7.5 0.0 21 44 200 223 197 231 0.87

4 7 0.23 1.8e+02 2.9 0.0 21 44 228 251 225 255 0.87

5 7 0.0056 4.3 8.1 0.0 21 43 256 278 249 287 0.87

6 7 1.3 1e+03 0.5 0.0 21 43 284 306 279 311 0.84

7 7 0.0046 3.5 8.3 0.1 21 47 312 338 309 342 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.22	1.7e+02	3.0	0.1	21	43	144	166	136	172	0.88
2	7	0.069	53	4.6	0.0	21	43	172	194	167	200	0.90
3	7	0.0086	6.6	7.5	0.0	21	44	200	223	197	231	0.87
4	7	0.23	1.8e+02	2.9	0.0	21	44	228	251	225	255	0.87
5	7	0.0056	4.3	8.1	0.0	21	43	256	278	249	287	0.87
6	7	1.3	1e+03	0.5	0.0	21	43	284	306	279	311	0.84
7	7	0.0046	3.5	8.3	0.1	21	47	312	338	309	342	0.88

Coding Sequence: ATGTTCACTTCAATGTCTAGTAACGAGGCTGAGGATAATAATAACATGTCGATGAACGAAGATAGTTATTCTAGTCAGAAAACAAAtctaacatttataaatatccCAACTAAGCATGAAGAAACAGAAAGTATTTGCTCGGACACTGCAAGTTTCAGtgaagaaacaaaaataataggTGCTACGAACACCACAATCGTTTGCGAAGGGACTGAAGGAAGTTTTAAaggttttaaagttttaaaactggATTTAGTGTGTTCCAGATATAAAATGCCACTGAACGCAGCATTAGATGAAAATCTTGTTATAAAATGTGACCCTTTTGAAAAGATCTATGTAAAACAAGAGAACGAAGATTACGACGCCTCATTGTTTTCCACGTATGACGATCACAATGACAGTGATAGCGAAAAACGTATTCATACCGGTGAGCAACAACATcattgtgacgtttgtaataagacaTTTTCCCGGTCAGGTCATCTGAATAGGCACAAACTTACGCATACTGGAGAAAAACCATACCActgtgatgtttgtaataaaactTTCACTCAACTAACTAATTTTAGTAGGCACAAACTtatacacactggtgagaaaccttataagTGTGAAATTTGTGATAAGACTTTCACCCAGGCAAGTAATTTTAGTAGACATAAGCTTACCCattctggtgagaaaccgtataagtGTGATGTTTGCAATAAAAAGTTCACCCAAACAAGTAGTTTACACAAACATAAACTtttacatactggtgaaaaaccgtaTAAATGTGATGTATGTAATGTGAGCTTCACCCAGTCCAGTAATTTAAATAGTCACAAacttacacatactggtgagaaaccatacaaatgtgacgtttgtgaTAAGACTTTCgcccattcaaattattttcgtaTACACAAACTTATACATAAAggggagaaaccgtatcaatgtgatatttgtgataaaaatttCACCCAGTCAGGTCATTTGCATAGACACAAACGTACCATGCATTCATTACAATTGTATACTATAGCTCAAGATACTGGATTAAAATGA
Protein Sequence: MFTSMSSNEAEDNNNMSMNEDSYSSQKTNLTFINIPTKHEETESICSDTASFSEETKIIGATNTTIVCEGTEGSFKGFKVLKLDLVCSRYKMPLNAALDENLVIKCDPFEKIYVKQENEDYDASLFSTYDDHNDSDSEKRIHTGEQQHHCDVCNKTFSRSGHLNRHKLTHTGEKPYHCDVCNKTFTQLTNFSRHKLIHTGEKPYKCEICDKTFTQASNFSRHKLTHSGEKPYKCDVCNKKFTQTSSLHKHKLLHTGEKPYKCDVCNVSFTQSSNLNSHKLTHTGEKPYKCDVCDKTFAHSNYFRIHKLIHKGEKPYQCDICDKNFTQSGHLHRHKRTMHSLQLYTIAQDTGLK

Sequence clustering based on sequence similarity using MMseqs2