Basic Information

Gene Symbol
-
Assembly
GCA_963582015.1
Location
OY757051.1:5833715-5856019[+]

Transcription Factor Domain

TF Family
AF-4
Domain
AF-4 domain
PFAM
PF05110
TF Group
Unclassified Structure
Description
This family consists of AF4 (Proto-oncogene AF4) and FMR2 (Fragile X syndrome) nuclear proteins. These proteins have been linked to human diseases such as acute lymphoblastic leukaemia and mental disabilities [1]. The family also contains a Drosophila AF4 protein homologue Lilliputian which contains an AT-hook domain. Lilliputian represents a novel pair-rule gene that acts in cytoskeleton regulation, segmentation and morphogenesis in Drosophila [2].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 7.5e-10 2e-05 24.6 0.0 5 81 28 106 26 117 0.82

Sequence Information

Coding Sequence
ATGAGGTTAAGGTACGACAAGTGGGACCGGGACcggggcgggggcggcggcAGTGGCGGTGGCTCGGGCGCGTGGTCCAGCCGCGATCGCGAGCGCGAGCGCGAGCGGCAGGCGCGCGCGCATCAGATGTCGCACGCGCACGCCGCCGAGCCCGACGCCTCGTCTCTCTTCCCGGCGCCAGTTAGGGTGACAGGGCACCGCGACAAAGTCAGCCAGCAGATCCAGCACAAGCTCGGCGACTACTTGCTCGCGCAGACCTTCATCGACGACCCCAGCAAGTCGATCGGCATCTGCGCGGAACCACCAAGTCCTGCACCATGTATACTACGAATGAGAATGGACACGAAGGTCCGTTAG
Protein Sequence
MRLRYDKWDRDRGGGGGSGGGSGAWSSRDRERERERQARAHQMSHAHAAEPDASSLFPAPVRVTGHRDKVSQQIQHKLGDYLLAQTFIDDPSKSIGICAEPPSPAPCILRMRMDTKVR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

90% Identity
iTF_00662233;
80% Identity
-