Basic Information

Insect: Wyeomyia smithii
Gene Symbol: -
Assembly: GCA_029784165.1
Location: CM056644.1:27578996-27580936[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.0041 0.45 12.8 3.3 1 23 59 82 59 82 0.93

2 15 0.00093 0.1 14.8 3.2 1 23 105 127 105 127 0.96

3 15 5.2e-06 0.00057 21.9 2.3 1 23 133 155 133 155 0.99

4 15 1.3e-05 0.0014 20.7 3.4 1 23 161 183 161 183 0.98

5 15 0.00015 0.017 17.3 0.2 1 23 189 212 189 212 0.97

6 15 9.7e-06 0.0011 21.0 0.9 1 23 240 262 240 262 0.97

7 15 1e-05 0.0011 20.9 0.1 1 23 273 295 273 295 0.96

8 15 2.1e-05 0.0022 20.0 1.5 1 23 300 322 300 322 0.98

9 15 0.0031 0.33 13.2 0.1 3 23 330 350 328 350 0.96

10 15 0.0095 1 11.6 0.2 1 19 356 374 356 376 0.86

11 15 2.1e-06 0.00023 23.1 0.8 1 23 384 406 384 406 0.99

12 15 5e-05 0.0054 18.8 0.5 1 23 412 434 412 434 0.98

13 15 9.4e-05 0.01 17.9 0.4 1 23 440 462 440 462 0.98

14 15 9.8e-05 0.011 17.9 1.0 1 23 468 490 468 490 0.98

15 15 0.0047 0.51 12.6 4.8 1 23 496 518 496 519 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.0041	0.45	12.8	3.3	1	23	59	82	59	82	0.93
2	15	0.00093	0.1	14.8	3.2	1	23	105	127	105	127	0.96
3	15	5.2e-06	0.00057	21.9	2.3	1	23	133	155	133	155	0.99
4	15	1.3e-05	0.0014	20.7	3.4	1	23	161	183	161	183	0.98
5	15	0.00015	0.017	17.3	0.2	1	23	189	212	189	212	0.97
6	15	9.7e-06	0.0011	21.0	0.9	1	23	240	262	240	262	0.97
7	15	1e-05	0.0011	20.9	0.1	1	23	273	295	273	295	0.96
8	15	2.1e-05	0.0022	20.0	1.5	1	23	300	322	300	322	0.98
9	15	0.0031	0.33	13.2	0.1	3	23	330	350	328	350	0.96
10	15	0.0095	1	11.6	0.2	1	19	356	374	356	376	0.86
11	15	2.1e-06	0.00023	23.1	0.8	1	23	384	406	384	406	0.99
12	15	5e-05	0.0054	18.8	0.5	1	23	412	434	412	434	0.98
13	15	9.4e-05	0.01	17.9	0.4	1	23	440	462	440	462	0.98
14	15	9.8e-05	0.011	17.9	1.0	1	23	468	490	468	490	0.98
15	15	0.0047	0.51	12.6	4.8	1	23	496	518	496	519	0.96

Sequence Information

Coding Sequence: ATGGAAGAATCCACTCAGATCAAAGTAGAAGAGCTTGTAATACTCGACACAAAGGatgagaaaactttttttgctaACAGCGAACTGTGTTCCGATGAAACCAACGTCCTAAGGAAAGTTTCTACGGATACTGATCTCCTAGACCATATGCCCCGGCACAGTAATGAGCGACCCTTTAAATGCACAATCTGTAGCAGAACGTTTAAGAATTCCAGAGGATTGAGGTTTCATGAAAACAAATACCACAAGGTCGATCCGTCCTCAAGTAATTGGAACAGTTCGAAATCGTGGAAGGGCAACGGGAAACTACTTTTCGCATGTGATATCTGCAGCAGAACATGCGTCACACCGGAGAGTTTGCACCACCATATGAGTGCTCATACAGGAGACCGGAACTTCCAGTGTGACATATGCGGACGACGATTCAGCGTTAAAAGACATATATCGACTCACATGAGAATACACCGCACAGATTGCAGGCATAAGTGCTCGGTTTGCAATAAAAAATTCACAAGTAATTTCAGTCTCGCAGATCATATGCTCCGTCACAGCGATGAGCGTCCCTTCAAATGTGACATCTGCGACACATTAATCAAGAGATCGGCAGATTTAATGCGTCATATGCAGAATGTCCATAATGTCGATCTCTTCTCAAGCAATGCGAAGAGTTTGGAACCAAGCCAAACTGATAAAAGCCGAAGCGAAGGTTCAGGGGAATACAACTGCGACATATGCGGGAAACAGTATACAACAAAAAATTCTCTTCGCTTACATCAGGAACTTCATCAGAGCACTGCAGTAAGATCCGAACGGAAATTTCAATGTGACATCTGTAGCGAAGCATTCACACAAGAATCAACATTAGCGCGACACATTGCAGATCACAGCACAAAGCGACACCAGTGTAAGATTTGTGGAAAAGGATATGCTCGCGCACACTGGCTCCTACTGCATATGACTTCTCATACAGAGGAAATACCTATTAATTGTGATATTTGTGGTATATCATGTGAGTCAGCTAAAGCTTTGATAGAACATAAAGCAACACACACCTCAAAGAGGTCGTATAAATGCAAAgtttgtggaaaaggattttcAGCAGTTCGGAGGCTCAGGGAGCATTCGATTTGCCATACTGAAGAGCGGCCTTTTAAATGTGATATTTGCGGGTCTGTATATAAGTCGTCTGATAGTTTGAGAGAGCATCAAAAAACGCACGCCCTTTGGAACCCATATAAATGCGATATTTGTGGGAGGAGCTGTTCGGGTCCTGGACGGCTCGAAATGCATATGACTAGTCATACTGAAGAACGACCTTTTAATTGCGACATTTGCGGGTCCGCATATAAGTCAGTTGCTAGTTTGAAAACACATCAGAAAACGCACATCTCTGAGAGACCACATAAATGCGAAATCTGCGGAAGAGGCTTTCTTCTTCCTTCCCAGGTAAAGCGGCACATGCGTAGTCATTCTGACGAACGGCCTTTCAAATGCAACATGTGCGACGGATCATATAAGTCAACTTTTATGCTGAAAATACATAGAAAAAAACACCATGACGGGTGTGACCCCTGA
Protein Sequence: MEESTQIKVEELVILDTKDEKTFFANSELCSDETNVLRKVSTDTDLLDHMPRHSNERPFKCTICSRTFKNSRGLRFHENKYHKVDPSSSNWNSSKSWKGNGKLLFACDICSRTCVTPESLHHHMSAHTGDRNFQCDICGRRFSVKRHISTHMRIHRTDCRHKCSVCNKKFTSNFSLADHMLRHSDERPFKCDICDTLIKRSADLMRHMQNVHNVDLFSSNAKSLEPSQTDKSRSEGSGEYNCDICGKQYTTKNSLRLHQELHQSTAVRSERKFQCDICSEAFTQESTLARHIADHSTKRHQCKICGKGYARAHWLLLHMTSHTEEIPINCDICGISCESAKALIEHKATHTSKRSYKCKVCGKGFSAVRRLREHSICHTEERPFKCDICGSVYKSSDSLREHQKTHALWNPYKCDICGRSCSGPGRLEMHMTSHTEERPFNCDICGSAYKSVASLKTHQKTHISERPHKCEICGRGFLLPSQVKRHMRSHSDERPFKCNMCDGSYKSTFMLKIHRKKHHDGCDP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01525591;
90% Identity: iTF_01525591;
80% Identity: iTF_01525591;