Basic Information

Gene Symbol
Aef1
Assembly
GCA_907269105.1
Location
OU026154.1:153291771-153292448[-]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.0016 19 6.5 0.4 20 46 96 122 81 125 0.80
2 4 1.1e-05 0.14 13.3 0.0 21 52 125 156 122 158 0.89
3 4 0.0039 48 5.2 0.1 21 51 153 183 150 184 0.87
4 4 0.00011 1.3 10.2 0.1 21 47 181 207 179 212 0.89

Sequence Information

Coding Sequence
ATGACTAATTGTGAAATCGTTATTGTTGCAACTACCGATGAACCAGCCACTGATTTACAAATACCCTTCAATGTAATAACATCGGCGGCAACAGTTTCAGCTACTGGTGTCACAACTACAACTCATCACCTCGCTCCACTGCAACAACATACagaacagcagcaacaacagcaacagcagcagcagcagcaacaacaacagcaacaacaattacTAACATCAGATGCTCTCCAGCAAGTGCAGGCGAGTGTGCTGCCACCTCATTTGGATCGTCCGCCCACCAATGGTCCCGAAAAGCCATTCCAATGTAACATTTGCGAAAGGCGATTTCGACAATTAAGCACACTAACGAATCATGTAAAAATTCACACCGGCGAAAAACCCTACAAATGCACGATCTGCGACAAAACCTTCCGACAATCGAGCACCCTCACGAATCACATGAAAATTCACACCGGCGAAAAACCCTTCATCTGTTCGTACTGTCCCAAGCAGTTCCGACAATTGAGCACACTAACTAATCACCTAAAAATCCATACGGGAGAGAAACCATTCGAATGTGCCGTCTGCAAGAAACAATTCCGCCAATCGAGTACGCTCAACAATCACATAAAGATTCACGTCATGGACAAGGTGTACATACCGGTGAAAATCAAAACCGAAGAAGACGAAGGGTGA
Protein Sequence
MTNCEIVIVATTDEPATDLQIPFNVITSAATVSATGVTTTTHHLAPLQQHTEQQQQQQQQQQQQQQQQQQLLTSDALQQVQASVLPPHLDRPPTNGPEKPFQCNICERRFRQLSTLTNHVKIHTGEKPYKCTICDKTFRQSSTLTNHMKIHTGEKPFICSYCPKQFRQLSTLTNHLKIHTGEKPFECAVCKKQFRQSSTLNNHIKIHVMDKVYIPVKIKTEEDEG*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01223723;
90% Identity
iTF_01521398;
80% Identity
iTF_01522097;