Basic Information

Insect: Vespula pensylvanica
Gene Symbol: -
Assembly: GCA_014466175.1
Location: CM025337.1:2308882-2315701[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 9.8e-17 3e-13 48.7 0.2 10 70 269 327 263 331 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	9.8e-17	3e-13	48.7	0.2	10	70	269	327	263	331	0.90

Sequence Information

Coding Sequence: ATGGACGGAACCGATGTGAATGGCGGGAACGCTAAAGTGGCGCGCGACGTTTCTAACCTAAACAGTGTTAGTATGCCGGATTTACAGGAATCTGAGAACGAAACGGCCGTCGTCGAGACCGTTGCTGATACCGCCACTGATATGGACGGTCAAGAAGTGAACGGTGATTTGAAAGGTTCTTCGAAGAAGACTCCTTCGACGGCGGTTAAAACTAAATTGCGCAAGTTCAAGGCCAATTCAACGAGCAGTATCGAGAACGATGTAAGCCTTTCCACAACGAGGGGGGGACGTAAGCGTAAGCTTTCGGAACCTGACGATGCTAGTTCCGAGGAATCCACCGAGTTTAATGGATTCGATTTACAAGGGATCGATGAATTCGATACGGGAAATCATTCATTGAAGAAGCTCATTGCTGAGGCAGATATTGCAGAGGCTCAATTTATGAAACGCTGTAGGTATTTGGTGCCAAAAAAGAACTTCGACGGTAGAAAAGATGAAGATCAAGACTCGGATGAAAATAAAATACGTGTATATGACATGGAACAATTCGATATTGATAAAATCAAAAAAGAAAGAGAATCTGATACAGATTCTATCGGTATAGCAAATAGCATAGAATTAGAAATGGAACAGCAGAAGACCGAAGAATCGTCTATTAAGTCTGTAAATTCGTCGTCTACTACAAGTAGTCCATCTGCGGTATCGCTGAAGTCTAAAGGAGGTAGGATATCGCGCGGCGCAAGTCCGGGAAGTGCGTTAAAACAAAAAACAACGATCGACATGTCAAATCCAGCTTTTAAGGAACCATTCAAGTATGGATGGAAACGGGAACTGGTATTCAGAGCTAGTAATGACTCGAGCCTTAAACGAATGGCTGATATATATTATTATACACCAAAGGGAAAAAAAGTAAGAAGTTTTAGAGAAGTAGCTGAATACCTTCATTCAAGAGAATTAACCATTGATAATTTTACATTCTTCAAAGAACCTATTGGCTTAGACGATCCTGAAAAAGAAATAATTCGAGATGCAAAGAGGATAAGGGGTTCAATAGGATCCGCATCTACGCCGCCGAGAAGGTCCTTCGGTTCTAAGAAAGTTATGAGCACGCGGAAACCTACCGAGGAATACGTTCCAGCATCGTCCCCCACACCAGCAGTTGCCGTTCCACAAACAGCAGTATCAACCACGCCTGCAAAAACCGCTGCCAGATCACCAAAAACAGCTAGCAGTTTCAAAGTTAAAGTGCCTGCAAAGAAAACTCCACAAATAACAGAAATAAAAACATCATCGGAGGAGAGAGATATGTTACCGCCACAACGAAACGCGGCGAGTACAAGAAGAAGTCAACAGCCAGTGGAAAAAGCACCACCTGTTAAAAGCAAACGATTATTAACGCCCAAAGTACAAGAACCATGCAGCATAAGATGTTCAACAAGTATGGGACTGATTCCCAGTTTACAGTGTCGCGTATGCCTTTGCTTATATCATCCTGAGTGCGTAGATGGCTTGGAATTTTCAGGAAGTGATGATTACATTTGTAAGAATTGTCAACAAGATTCTACAGAAACTCATCAACACCAATCGATGAATCCATCTTTAACACCACCTCCGTTGATTCCAATCAGCATGTTAGGCACACAAAATGCAAAACAAAAGCCACAAGCAAGCTTAACTCCACCAAAATTGCAAAGAATTCCAAAATCAGAGAACGCGGATATACAGTCACGTAGTACTAGTAAATTTTCTAAAACAGCAACAACAACGACAACGACAAGTTCGACATCGCCGTCGGAGAAGAAGGAGGATACTTGGTTTCCTCAATCAGAGAATGAATTTTTGCAAAGTCATGATGGAATATTACCAAAACCAGCGCAAAATATTGCTTTGATGGGAGGCAAAAGATATATAGTTGTACCAAAGAATAATGCAATGGCAGTTCAACCAGCCATTACAGTAAAACCTGATAAAATTGGTGACAAACCACCGATGTTACAGGAAAGTTCTTTAATTGATATATCCAATACAATGGAAAATTCAACCATTACAAATATAGGTATTTCACCTTCAACAAAAATATCTGGTGCCAATGATACGACTGAAAATGTCTATGATAGAGAATTGTCGAAAGACGTTTCTGCTTCGTGTGGATCTTCTGATGACACGAATGAAACGTTGGACAGTAATATTAATACGAATACTTTGATCAATACGAATACGTCTCTGTTAGAAAATCAAATTTTAAATGCAAAAGCATATTCATCGCTTGAAACAAGGAGAACGAGTACTAGATCACCTAATAAAAAACCAATGTCTTCAATGGCAATACAAAATAATATAAGTACATTTGGTATAGACAGTGAAGTGACTAAAACAGATATAAAACAAATAGTAATTAATACGAATGTAGTGCAGATGGGTAATAGAAGAAAACAAAATCAACAGGAGTCAAATCTACAACATCACTTTATGGATAATGTATGTGCGGGTTATCATGCATTATTACGAATTTTTCAATATCTCAAGGTGCAAGAGTTGTTACGCGCAGCTCGTGTTTGTAAAATGTGGCGAGATTTGGCTGCGCATCCTTCTTTGTGGAAAACAGTAAGAATGAAGAATAGCCAAGTAACGGATTGGGACGGTTTAGCAGATACATTACAAAGACACGGCACACAGCATTTGGATCTCAGGAAAATGCTTGTAGCTGGAGAATCAGATAGTATTTGGAGAAAGTTTCTCTCTGTAATACCTAGAGTAACCAGCCTCGTTAAGTTAGAGTTATGTAGATGCCCTGTTATGGTAGTAGAAGAAGTCATTAAAAGTTGTCCGCAATTACAAGTATTGAGTGCAATGACAATCAAATGTGACTCTTTAAATTTGCAATCTATTGGCAATCTTAAACATTGTCAAGAATTAAGACTCAAGGCAATAAGTGGAATGTCTTTGCAAGAAGATCTTACACCACTACAAGAATTAACGCAATTAACACAACTGAGTTTAACGTCAGTCAAAGAACTTGGAAAGAAGAAAATTGATATAATACAAACATTAATAAATTTAGAAACGTTGGAGTTGGGGGAGTGTTCAGATTTTCCAGACAAGTTTGGAACATCGGTTTTAATAAAATTACAAAAACTGGAACGCCTCCGACTCGAAAAGGGCCAAGGATCTTGCTGTACATTTGATATTTTAGAAGGTGTTTCAAAATTGGGAAATTTAAACCAAATGGAGTTAGTTAATTTTGATGTAAAAAATGGTTTTGATAAGTGTCTTGCTAATTGTAAAAATATTAAGAGGTTACTGATTATACCAACCTACATATCACAATCAGCTACTTCAAATAACATGGTACTTGGTGGCGTTACCGAATTGTCACACAATTTAACGCATTTTGTTTGGGGCGTAACTCTTGAATTACTGAGAGTTACGGAATTATTTGTTGACCAGTGCAATTTGATGAATAAACAGGTTACTGGTGATTCTATACCAGTTTTGAAACCAGTACCCTGTTTAAAATTAATCGAAGATGTCGAGGATGAAAATGATAACCAAAAAGGTGAAGATAAACAGTTAAATATGACGAGTCCACAAGTCGATATTCTACCATTACCACAACTTCAAAAACTTCTTTTAACTGCATTACCTAAGACACGTGTTAAAATTCTAAAGATTCCCTTCCATGCCACATGGCGACAGAGCATTTCTGATACTACTACACAATAA
Protein Sequence: MDGTDVNGGNAKVARDVSNLNSVSMPDLQESENETAVVETVADTATDMDGQEVNGDLKGSSKKTPSTAVKTKLRKFKANSTSSIENDVSLSTTRGGRKRKLSEPDDASSEESTEFNGFDLQGIDEFDTGNHSLKKLIAEADIAEAQFMKRCRYLVPKKNFDGRKDEDQDSDENKIRVYDMEQFDIDKIKKERESDTDSIGIANSIELEMEQQKTEESSIKSVNSSSTTSSPSAVSLKSKGGRISRGASPGSALKQKTTIDMSNPAFKEPFKYGWKRELVFRASNDSSLKRMADIYYYTPKGKKVRSFREVAEYLHSRELTIDNFTFFKEPIGLDDPEKEIIRDAKRIRGSIGSASTPPRRSFGSKKVMSTRKPTEEYVPASSPTPAVAVPQTAVSTTPAKTAARSPKTASSFKVKVPAKKTPQITEIKTSSEERDMLPPQRNAASTRRSQQPVEKAPPVKSKRLLTPKVQEPCSIRCSTSMGLIPSLQCRVCLCLYHPECVDGLEFSGSDDYICKNCQQDSTETHQHQSMNPSLTPPPLIPISMLGTQNAKQKPQASLTPPKLQRIPKSENADIQSRSTSKFSKTATTTTTTSSTSPSEKKEDTWFPQSENEFLQSHDGILPKPAQNIALMGGKRYIVVPKNNAMAVQPAITVKPDKIGDKPPMLQESSLIDISNTMENSTITNIGISPSTKISGANDTTENVYDRELSKDVSASCGSSDDTNETLDSNINTNTLINTNTSLLENQILNAKAYSSLETRRTSTRSPNKKPMSSMAIQNNISTFGIDSEVTKTDIKQIVINTNVVQMGNRRKQNQQESNLQHHFMDNVCAGYHALLRIFQYLKVQELLRAARVCKMWRDLAAHPSLWKTVRMKNSQVTDWDGLADTLQRHGTQHLDLRKMLVAGESDSIWRKFLSVIPRVTSLVKLELCRCPVMVVEEVIKSCPQLQVLSAMTIKCDSLNLQSIGNLKHCQELRLKAISGMSLQEDLTPLQELTQLTQLSLTSVKELGKKKIDIIQTLINLETLELGECSDFPDKFGTSVLIKLQKLERLRLEKGQGSCCTFDILEGVSKLGNLNQMELVNFDVKNGFDKCLANCKNIKRLLIIPTYISQSATSNNMVLGGVTELSHNLTHFVWGVTLELLRVTELFVDQCNLMNKQVTGDSIPVLKPVPCLKLIEDVEDENDNQKGEDKQLNMTSPQVDILPLPQLQKLLLTALPKTRVKILKIPFHATWRQSISDTTTQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01513475; iTF_01514825; iTF_01232999; iTF_01089996; iTF_01512186; iTF_01234345; iTF_01232401; iTF_01235027; iTF_01233656; iTF_01512830;
90% Identity: iTF_01514825;
80% Identity: -