Vger004030.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Vespula germanica
Gene Symbol
gcl
Assembly
GCA_905340365.1
Location
HG996531.1:7822584-7824621[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 2.2e-17 4.4e-15 55.5 0.0 2 109 61 169 60 170 0.91

Sequence Information

Coding Sequence
ATGGGAAGCTATATGAGTAGAATTGCGTCTATGTCAAATACGGCAGTACATTCTGTTTATCGAGGTCGTAAACGAAAATGCATCGAAGAAGATGATTTCGATTCTGAATCTGAATACATCGATCGAACACTTCAAACGCCTAAAAAGAGAAAATTACTTACAACcgcacaatatatatataagacttTGTtccaagaagagaaaggaagtgATATAACTGTGCTCATGTTAGGAAGAGCATGGAGATTACATAAAGTTTATATTAGTCAaAGTCCATATTTTGCAAGTATGTTTTCTGGATCTTGGAGAGAAGCAAATGAAACTGTAATTAGCGTTGAAATTGCTGATCCTAATATCACATTAGATTcTCTTTTAACAGTATTAGGATCATTTTACCAAGACGAAGTCAGCTTAGAGCCAAAAGATGTCATTTCAATTTTAGCTACATCTACTTTATTTCAATTACAAGGATTGATTGATCAATGCACCGATATTATGATTGAAACTACAAACATTAAAACTGTTGTTCCATATTACAATGCAGCGGTTTCATATGGTGTACCTGCAGTTAAAATGGCTGCTAAAAGATGGTTGGAAGTTAATTTGTTAGGATACGGATGGTTACATCCAACATTTTTACAAGAAATTACTCCAGATTTAATGGCAGAATTAATTGTTAGTCCGGATTTGGTGGCTATGCAAACagaattttgtatatatatgatgctACGTGTAtgGCTGTTTGTACATCTAAAAAATAGAGATGAGACAGTAGAGATGGATGAATACTTTAGAAACCATACATGGACAGAACCTTTTCTAACGACAGAGGAAGGCAAAGAATATGCAACTCCTTTCAAAGCTTTAAGAATGAAATATCTACTTTTACATGATCAAgatgttaaaattttatacagtGATGATTTAATACCTCCTAGTTGGTTACATGATGCATATAAAGAACAATGGTTACATTTATTAAGAATTGATGCTAGCAAAGATAAAGGACCTAAACaaatgagtgagaaagaattttatcaAGAATGTTTTCGATGTGGCCGATGTGTTGAGAAACCCGGTGAACATATCTGGAGATGGACAGCATTTCATTTTGGACTGGATCTTGTTGTATGTTTAGATACTACAACTTTGCGTATCAAACGAAATCACAGATTAGATTCAGATCATATTAAAGCAAAtcataataaacataatattattttaaaggTAACATTGATTTCATTGGATGAACAACGGCAAATTAAACATATTCAATCTTCCGGAATGCTTAGGTTATCGCTACACAAAAATGAAGagAAACAGGTAATGTCTCTGGATAAACAATTAACGTATCCTTTGTACATATCTGTTAATATGCAAGTAGTAAcaccatttttatttaatgaggaagagaaattaaatgatGTTATGCTTGTGGATACTTAG
Protein Sequence
MGSYMSRIASMSNTAVHSVYRGRKRKCIEEDDFDSESEYIDRTLQTPKKRKLLTTAQYIYKTLFQEEKGSDITVLMLGRAWRLHKVYISQSPYFASMFSGSWREANETVISVEIADPNITLDSLLTVLGSFYQDEVSLEPKDVISILATSTLFQLQGLIDQCTDIMIETTNIKTVVPYYNAAVSYGVPAVKMAAKRWLEVNLLGYGWLHPTFLQEITPDLMAELIVSPDLVAMQTEFCIYMMLRVWLFVHLKNRDETVEMDEYFRNHTWTEPFLTTEEGKEYATPFKALRMKYLLLHDQDVKILYSDDLIPPSWLHDAYKEQWLHLLRIDASKDKGPKQMSEKEFYQECFRCGRCVEKPGEHIWRWTAFHFGLDLVVCLDTTTLRIKRNHRLDSDHIKANHNKHNIILKVTLISLDEQRQIKHIQSSGMLRLSLHKNEEKQVMSLDKQLTYPLYISVNMQVVTPFLFNEEEKLNDVMLVDT*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01514273; iTF_01514933; iTF_01232506; iTF_01090107; iTF_01233117; iTF_00633759; iTF_01003684; iTF_00380491; iTF_01006416; iTF_01005394; iTF_01004470; iTF_00382011; iTF_00381273; iTF_00379775; iTF_00379008; iTF_01454308; iTF_00864085; iTF_01498331; iTF_00391453; iTF_01394503; iTF_01389608; iTF_01392169; iTF_01390479; iTF_00200944; iTF_01391345; iTF_01392923; iTF_01393692; iTF_01255816; iTF_00393715; iTF_00734058; iTF_01512938; iTF_01512291; iTF_00230795; iTF_00221377; iTF_01102956; iTF_00140705; iTF_00216513; iTF_00798721; iTF_01419745; iTF_00414466; iTF_01102210; iTF_00059587; iTF_00215139; iTF_00862691; iTF_00982403; iTF_01057795; iTF_00058084; iTF_00962628; iTF_00983077; iTF_00217190; iTF_00088167; iTF_00217863; iTF_00232711; iTF_01069095; iTF_01234471; iTF_01299431; iTF_00231433; iTF_00141322; iTF_00142570; iTF_00219914; iTF_00263658; iTF_01497610; iTF_00225355; iTF_00905547; iTF_01169291; iTF_01421035; iTF_00084684; iTF_00118124; iTF_01056204; iTF_01235148; iTF_01066381; iTF_00652974; iTF_00841230; iTF_01057038; iTF_01424494; iTF_01539726; iTF_00625615; iTF_00966127; iTF_00051152; iTF_00226032; iTF_00873904; iTF_00963312; iTF_00215825; iTF_00222641; iTF_00262801; iTF_00266609; iTF_00397457; iTF_01101489; iTF_01129489; iTF_00141938; iTF_00863378; iTF_00983698; iTF_01100754; iTF_00184051; iTF_01233779; iTF_00963956; iTF_00964596; iTF_01067732; iTF_01070484; iTF_01103700; iTF_01420372; iTF_00684277; iTF_00721397; iTF_00228086; iTF_01067063; iTF_01418455; iTF_00087320; iTF_00228792; iTF_00226713; iTF_00398233; iTF_01207513; iTF_01364794; iTF_00220699; iTF_00229467; iTF_00961947; iTF_01417819; iTF_00439644; iTF_01509020; iTF_00085533; iTF_00088957; iTF_00265885; iTF_01065693; iTF_01306653; iTF_00227390; iTF_00232094; iTF_00316926; iTF_00629246; iTF_01069790; iTF_00219231; iTF_00222015; iTF_00761087; iTF_00829663; iTF_00058848; iTF_00230144; iTF_00233344; iTF_00828928; iTF_01068416; iTF_01419104; iTF_01123172; iTF_01122569; iTF_00086439; iTF_00866127; iTF_00865441; iTF_00860518; iTF_00861288; iTF_00762667; iTF_00763344; iTF_00864755; iTF_00862008; iTF_00866813; iTF_01130959; iTF_00773942; iTF_00306397; iTF_00223313; iTF_00676138; iTF_00218544; iTF_00223997; iTF_00224670; iTF_01000721; iTF_00687340; iTF_00996494; iTF_01002227; iTF_01560596; iTF_00997173; iTF_00452062; iTF_01001536; iTF_00024724; iTF_00183394; iTF_00938893; iTF_01413505; iTF_01412482; iTF_00060483; iTF_00718755; iTF_00939752; iTF_01303593; iTF_00159247; iTF_01049071; iTF_00174452; iTF_00719572; iTF_01200340; iTF_01414356; iTF_01411675; iTF_00175868; iTF_01048349; iTF_00175200; iTF_01120334; iTF_00882329; iTF_00879884; iTF_01538108; iTF_00770504; iTF_01199539; iTF_01198804; iTF_00754899; iTF_00361021; iTF_00360332;
90% Identity
iTF_01234471;
80% Identity
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