Vger004974.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Vespula germanica
Gene Symbol
Hr39
Assembly
GCA_905340365.1
Location
HG996532.1:9116693-9120136[+]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 5 4 1.4e+04 -6.2 5.8 131 157 64 88 24 115 0.52
2 5 1.3 4.8e+03 -3.7 5.9 76 163 273 386 219 406 0.56
3 5 4 1.4e+04 -11.9 14.3 68 145 404 487 358 530 0.42
4 5 5.8e-08 0.00021 20.5 0.1 1 22 599 620 599 641 0.87
5 5 9.3e-70 3.3e-66 224.1 0.5 201 408 790 996 623 996 0.89

Sequence Information

Coding Sequence
ATGTCGGAGCAAAACGGGCCTGGCGATGGCCCGGGACCTGGTCCAGGTTGGTGGCCGTCGACACAATCTTGGAAGTCGTCTGGTTCCGTCGGATCAAACTCCTCGTCGTCTTCTACCTCCGGTACAAGCGGCGGCTCCACTTCCGTTTCTGCCTCCtgcgccaccgccgccgccaccgcacCCACCACCGGATCGGCCTCGTCAGTCTCACCGACGTCCTCCTCCACCTGCTGTTCCTCCTCATCCATCGGCAATTCTACGATGACTACTACTCGTTCTACGGAGGCAGGGAAGAACGTTTCTGTAACTGCGATCAATGTCCCACCTACTCATGAAATGCATGAtgGCAAAGGCATCTGTAAGTATCTAGGAGGTCAAAATGGCGTGACGGTGTCCGTAGTTTCAAATTGCGGCTCGGTACTTGGCTGTACGAGTAGTACCAGCAGCGTGGGCTCGCATGGCATCGGTATCGGTATTCTCGGTTCAAATGCCACGGATATCGACGACGCGGACGACAGCGACGGTGAAATAAGCAAGATCGACTTCCGTGGTGTCAATCTGCGAAccaagaagaaacgagatatCTCGGTAAATCAGAGCGGTGAGAAAATCGGCGATTGCGATGGCGAAGGTGAAAGCGGAGCTTGCGACGGTAACGATACGTCCCAACAGCAACAACCAGAGAGACCTATGTCATGGGAAGGAGAGCTGTCCGATCAAGAGATGTCTTCGAACACCCTCACTAATCAGGATCAACATGAGGAAACATCGATGGAAGGTGTTCAAGTTTGCGGTTCCAGTCCCGGACCTGTAGAGCAAAAGTTTCCGATAAAGCCAGAACCAGACTTTCGGTCAAGTCCAGGATACACGCTTGGTTCTTTTCACGAAGGGAATTTGTCTTTAAGTCACAACCAACAATTACAGCAACAACGTGGTATCGAAAATCTTGAACAAACGCAACAGAGCGACCTACCTCTTCTCGTGGGAAAACTACTTGGTGGATACAATAGTTCCACTCCAAATCACAGTCCGGTTCTTAATCCGAGACATCACTTGACCAAGCACAGTCACACGCGATCGCAGGTACCATCACCGGATTCCGCGATTCATTCTGCCTACAGTGTCTTCAGTTCTCCAACCCAAAGTCCTCACGCTGCGAGACATTCCGCCTTAGGAGCAGGAAGCCCCATTCCTTCTTCCTCGCTCTCCTTATCTCGACATAGCTTCAATAATTCGACGTCCTCCTtatcactctccctctctcactcgctctcGCGTAATAATTCAGATGCTTCGAGCAGCTGTTACAGTTATGGCTCTTTGAGTCCACCTACGCATTCTCCCGTCCAACAGCCTCGACATCCGCACGCTCACTCGCAACATCAGCATCAGCAAGTAGCACAAGGTAGTCCTTTGCATCTCCCAACGGTTGCTGCTTCGGCCGTGAGCGCGCACCATTACTCCTCTTCCGCACCAGGGTCAGAGCTTTCCTCGGATGGACATCCTGGAACGGAAGATCAAGAAGACTGTAGAATACCTGCTGCACCATCGGGTATCTCCACACGACAGCAGTTAATTAATAGCCCCTGTCCGATCTGCGGCGATAAGATCAGTGGATTTCATTACGGTATCTTCTCGTGTGAATCGTGCAAGGGCTTTTTCAAGAGGACCGTCCAGAACCGCAAAAACTATGTGTGCCTTAGGGGTGCAGGTTGTCCTGTTACCGTTGCCACAAGAAAGAAATGCCCCGCTTGTCGATTCGACAAATGCCTCAATATGGGAATGAAACTCGAAGCGATTAGAGAGGATCGTACCAGAGGTGGTAGGAGCACTTATCAATGTACATATACTTTACCGGCAAATCTCGTTGGTAGTCCTGCGAACAACATGACGGCGAGCGATAAGATGAACGCTGCTGGTAACTGCAGTCCTGCACCGCCCGGTAGCGAACATCATTATTCCGTTAGACATCATTCGAATCACTCGTATAAAGTACAAGTAGTACCGCAGCTTTTGCAGGACATCATGGATGTGGAACATCTTTGGCATTACAATGACAGTGATCGTATAACTGGTATTCAATCTGGTGTGATAACTTCTGGTGGAACTAGGAGCGCTCCTGCCAGTGACATGTTGTTAGGAAGCGGAAACGGTGGAGGAACTGGCGCTTCTGCCGGTCGAAATGGATCCGCTACCAATGGCTCTGGTACTGATTGTCCCACCAACGGGCATGCTagtaacaatattaatagtaGAAGGGAAGATAATACCGCAAGACCTTGTCCGACTGGCTCGGCTTCCACCGGTAGCCACGAACAATTATCCGCTAACGCTGGTAATGTTAGCAACTGTAATTCCCAAATGTGCGGGAATTCTAATGGTAATCCATCGCAACATCCGGACTTTCTTTCGAATCTTTGCAATATCGCCGATCATCGTCTGTATAAGATAGTTAAATGGTGTAAGAGTTTGCcacttttcaaaaatatttcaatcgacGATCAGATCTGTTTACTGATCAATTCATGGTGCGAGTTGCTGCTCTTCTCTTGTTGTTTCCGTAGTATGAGCACTCCTGGTGAAATAAGGGTATCTCTCGGCAAGTCGATCACTTTAGAGCAAGCAAGGCAACTTGGTTTAGCGACTTGCATCGAGAGGATGCTCGCTTTCACCAATAATTTGAGAAGGCTAAGGGTGGATCAATACGAATACGTAGCGATGAAGGTGATAGTGTTACTTACGTCCGACACCAGTGAGTTAAAAGAACCCGAGAAAGTTAGAGCTTCTCAAGAAAAGGCTTTACAGGCGCTTCAACAATATACCATTGCCAGGTATCCAGAAATGCCTGCCAAATTTGGTGAACTCTTATTGAGGATTCCGGATTTACAAAGGACGTGTCAAGCAGGAAAGGAATTATTAAGTGCAAAGCGTGCGGAAGGAGAAGGCAGCTCGTTCAACTTATTAATGGAATTATTGAGAGGTGATCATTAA
Protein Sequence
MSEQNGPGDGPGPGPGWWPSTQSWKSSGSVGSNSSSSSTSGTSGGSTSVSASCATAAATAPTTGSASSVSPTSSSTCCSSSSIGNSTMTTTRSTEAGKNVSVTAINVPPTHEMHDGKGICKYLGGQNGVTVSVVSNCGSVLGCTSSTSSVGSHGIGIGILGSNATDIDDADDSDGEISKIDFRGVNLRTKKKRDISVNQSGEKIGDCDGEGESGACDGNDTSQQQQPERPMSWEGELSDQEMSSNTLTNQDQHEETSMEGVQVCGSSPGPVEQKFPIKPEPDFRSSPGYTLGSFHEGNLSLSHNQQLQQQRGIENLEQTQQSDLPLLVGKLLGGYNSSTPNHSPVLNPRHHLTKHSHTRSQVPSPDSAIHSAYSVFSSPTQSPHAARHSALGAGSPIPSSSLSLSRHSFNNSTSSLSLSLSHSLSRNNSDASSSCYSYGSLSPPTHSPVQQPRHPHAHSQHQHQQVAQGSPLHLPTVAASAVSAHHYSSSAPGSELSSDGHPGTEDQEDCRIPAAPSGISTRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAGCPVTVATRKKCPACRFDKCLNMGMKLEAIREDRTRGGRSTYQCTYTLPANLVGSPANNMTASDKMNAAGNCSPAPPGSEHHYSVRHHSNHSYKVQVVPQLLQDIMDVEHLWHYNDSDRITGIQSGVITSGGTRSAPASDMLLGSGNGGGTGASAGRNGSATNGSGTDCPTNGHASNNINSRREDNTARPCPTGSASTGSHEQLSANAGNVSNCNSQMCGNSNGNPSQHPDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITLEQARQLGLATCIERMLAFTNNLRRLRVDQYEYVAMKVIVLLTSDTSELKEPEKVRASQEKALQALQQYTIARYPEMPAKFGELLLRIPDLQRTCQAGKELLSAKRAEGEGSSFNLLMELLRGDH*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01513512;
90% Identity
iTF_01234404;
80% Identity
iTF_01513512;