Basic Information

Insect: Vespa crabro
Gene Symbol: Znf423
Assembly: GCA_025728115.1
Location: JAITYU010009997.1:127784-139782[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 7.7e-06 0.00055 19.9 1.5 1 23 92 114 92 114 0.98

2 19 0.19 13 6.1 4.9 1 23 120 142 120 142 0.98

3 19 1e-06 7.2e-05 22.7 4.1 1 23 148 170 148 170 0.99

4 19 0.00021 0.015 15.5 0.2 1 23 176 198 176 198 0.99

5 19 0.001 0.074 13.2 0.7 1 23 354 377 354 377 0.96

6 19 0.28 20 5.6 0.0 2 23 388 410 387 410 0.88

7 19 0.17 12 6.3 0.1 3 23 474 494 472 494 0.97

8 19 0.0014 0.1 12.8 0.4 1 23 506 528 506 528 0.96

9 19 0.0075 0.54 10.5 0.4 1 23 537 560 537 560 0.93

10 19 3.5 2.5e+02 2.2 0.2 1 23 565 588 565 588 0.91

11 19 2.2 1.6e+02 2.8 0.3 2 23 662 683 662 683 0.95

12 19 0.0052 0.37 11.1 0.3 1 23 688 711 688 712 0.94

13 19 3.1 2.2e+02 2.3 0.1 2 23 777 800 776 800 0.81

14 19 2.4e-05 0.0017 18.4 1.1 2 23 817 839 816 839 0.97

15 19 1 73 3.8 0.6 1 12 848 859 848 871 0.76

16 19 0.01 0.74 10.1 0.1 2 23 1069 1091 1068 1091 0.94

17 19 0.92 66 4.0 0.2 1 23 1102 1125 1102 1125 0.93

18 19 0.0068 0.48 10.7 0.1 2 23 1168 1190 1167 1190 0.94

19 19 0.48 34 4.9 3.1 1 23 1197 1220 1197 1220 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	7.7e-06	0.00055	19.9	1.5	1	23	92	114	92	114	0.98
2	19	0.19	13	6.1	4.9	1	23	120	142	120	142	0.98
3	19	1e-06	7.2e-05	22.7	4.1	1	23	148	170	148	170	0.99
4	19	0.00021	0.015	15.5	0.2	1	23	176	198	176	198	0.99
5	19	0.001	0.074	13.2	0.7	1	23	354	377	354	377	0.96
6	19	0.28	20	5.6	0.0	2	23	388	410	387	410	0.88
7	19	0.17	12	6.3	0.1	3	23	474	494	472	494	0.97
8	19	0.0014	0.1	12.8	0.4	1	23	506	528	506	528	0.96
9	19	0.0075	0.54	10.5	0.4	1	23	537	560	537	560	0.93
10	19	3.5	2.5e+02	2.2	0.2	1	23	565	588	565	588	0.91
11	19	2.2	1.6e+02	2.8	0.3	2	23	662	683	662	683	0.95
12	19	0.0052	0.37	11.1	0.3	1	23	688	711	688	712	0.94
13	19	3.1	2.2e+02	2.3	0.1	2	23	777	800	776	800	0.81
14	19	2.4e-05	0.0017	18.4	1.1	2	23	817	839	816	839	0.97
15	19	1	73	3.8	0.6	1	12	848	859	848	871	0.76
16	19	0.01	0.74	10.1	0.1	2	23	1069	1091	1068	1091	0.94
17	19	0.92	66	4.0	0.2	1	23	1102	1125	1102	1125	0.93
18	19	0.0068	0.48	10.7	0.1	2	23	1168	1190	1167	1190	0.94
19	19	0.48	34	4.9	3.1	1	23	1197	1220	1197	1220	0.95

Sequence Information

Coding Sequence: ATGCTGTTCAAGGGCAATAGTTCGAGGTTGGAATTACTTATTGGGAAGATCCAGGCACATAAGGAACCTTCGCAGGAGGAACCTCACAAATCCAAAGAGGCTTTGGGTACTGGAAGTTCTTCTTGGCATAGCGAAGATGGCGGACCAACTTCTCGAAGAGGAGGAGAAACACCATCTTCTTGTGCGACGCCAACTTCTGCGAGCTTTCCGTCAGAGCCAGAAATCGACGGTGAAGTTGGAATTGGTACCGACGGTAACAATCCAACTGCTCCTTATCCTTGCCAATTCTGTGATAGGACTTTCCCACGATTGAGTTACCTCAAAAAACATGAACAGAGCCATGGTGATCAAATGCCGTACAGATGTAGTTGGTGTTCGAGATTGTTCAAGCATAAGCGGAGCAGAGATCGTCACGTGAAGCTGCACACGGGGGACAGGAGATATCGCTGTTCACATTGTGAAGCAGCCTTTTCCAGGAGTGATCATTTGAAAATACATATGAAAACTCACGATACGCAAAAGCCGTACCAGTGTACGGCATGTTCGAGGGGATACAATACGGCGGCAGCATTGACTTCTCACATGCAATCGCATAAGAAACATCACCAAGGAACAAGTAACAATAGTAACAAGCTTCAAGATTCGGATTATGGTAGAAGGAGCGTCTCTTCTCACAGTACGTCCTCTCCACCTGTACCAAGTTCGCCTTCGCCTTCGTTAAACTTAAGTTTAAATCCGAAAAATACTTTGAAGGCACCACTAGGAACTTCTTGTAGTGCCTCGACAACGCCGATACTAAATTCCCCTTTGAAATTAGCTTGCATGTATTGCACCAGAGATTCGTTCAGTTGTATGCAACAACTACAAATGCATGTCCACACGATGCACCAAGCGATTCTAAGCGGAGAAAATCTTGTCGTAGCACCGTCTCCGAGTAGAACTACCGATTCGGTCGTTGATTGTTCTCGTGATAAGCTATTGGATCGATCCGATGGCATTTCGAAGGATCAAGAGAAAAAGTACGAGGAAAGATCGATGGAAAAGGATTATAAAAATACTTTTACTTGTTATCAATGTACTATGAAATTTTCGAGTTTAGCCACATTGAGAGACCATCTGATTTCTATACATAGAACTGATGCCTTTGGTACGTCCTTGATAATGTGCCCTCTATGCGGTATCCCATGTAACTCTGCAGCAGCTTACGCCGAGCATTACGTTCTTCAACATTGCGAAAATCGTCGAGTAGCTCCGCAAAATCCTCAAGAATACATAGATCCTAAATTAAATGGAGTCTACGATACGAAAGGTATGAGATTACAAAAAAATAGAGAACAACAACCTATGTTAGAACCGGCTGATCTCACAAGTAAACACATTAAATCGTGTGAAAGTAATTACACGTCTAGTACGCTACTTTGCGGCCAATGCGGTGCAGCTTTGAAGGATTTCGAATCTTTCCGGGAACATCTTGCCAGACATTTGCAAGCCGATCATCGAAACGAAGCTGCAAGATATCTCTGTCCAAAGTGTGAAACGAGTTTTCAAAATAGAGAAGACATGTTGGCACATTTAACGAAACATTATTTGGGCCAAATTAGTAAGGAATATGCTTGTTCCGCTTGTAAGAAGTTATATCCACATCCTGATCTACTTCAAAGGCACCTTTTGGATAGTCATGCTCATCATCTTTACAGATGTGCACTCTGTAGAGACACCTTCGATTCTAGAGTAGCGATTCAAGTACATTTTGCTGTTAAACATAGCCAAGAATGTAGAATATACAGGTGTAATGCTTGTACGGCACCAAATAATGAAAATTCACCTGGAAATGCACCTGGCGAAGGTCGAAGTTTCTTCAGAAGCGAAAGCGAGATGGCCAATCATGTTAGAAACATTCATGCGCCGCCGGCGATGGCGAACAATAGCCCGATTGCCAGGAGTCCAGCTTCTACCCCAGGAATGACTGTCAATTCTGGACCTAGATGTGTCTTTTGTGGTATCTACTGTGGTTCTGAACTCGAATTACAGCTTCATTTGGCAAGCCATTCTACTAGTCTTTATAGATGTCCTATTTGTAGAGAAGGTTTTGCCGTTGAATTCTTATTGGACAGGCATATCACTCAAGTACATCATGCTGGCGAACATCAAATAATAAATGCACGAAATAATCCACGAGAAAATGGACGGCTTCATCGTCATCCTAGGTCTCAAGAAGAGGTAAAATCACAAAAGAGAGGACGTTCACCAGCCTCGAGCAACAACAATTCTTTGAACCAACGTGACAATAACAACAAAAGACCAAACTTCGGTGTATCAGGAGGACAACAATGTGAGCTATGCGAGCGTGGTGAATTCGCAAACGAAGCTGAACTACAAGCTCACAAAAAGTTAGCTCACGCATCGTCAAAAGTTCCAAGCAAAAGTTCTTTATCGAATGTGAGCATGACTTGTGCTTATTGTGGGGAGGTCTGTCGATCAAGAAATGAATTGGAATCTCATATGAGAATGCAACATACCTCGAGCGAGCCTGGCGGCCGACATAAGTGTAATATCTGTGACGAAGTCTGTCCTTCGGGCGCAATTTTGGCTGAACATAAGCTTCAGAAACATTGCAAGATTCAATTAAGCGATACTTGTGTCGTTTGTCGTGGAAATTTAACGACCGAAGCGTTATTCCTTGAGCACGTACAAAGACACAGCTTGGAAAATGTGGATCCGCAACAAAGACTGGACAATTCTTTACCTCATCTTCCAGCGCCATGTGTTGTTTGCAGACAAACTCTTATCAGCGATCTGGAATGTCGCCTTCACGCTCGACATCATCTTAGAACATCCACTAGCTCTCCGAATACGAGTTCTAGTCCAAGCCCTAAACAAAAGCCCCTCAATCCAAATTGTTGCCTTTGCTTACGAGAATTCTCTACTGAAGACTTCGTCAATCTTCCTCCTAATCACTTTAGTGGAGGACAATCTCTTAAAGTTTGCAAATCTTGCTATGTCAGATATTCTCAAGGTCTACCAATTTTGAGTTCACCTTACGAGCATGCTCGTAATATTAATAATAAGTGCGAACGTTCATGGATCAAGGATAAAGATCTTCAATGGGATGGCTCCGGAGATAGATGGGATACGGATCGTGGTTTTAAAAACGAAGATCGTTCGATCAACGATCAAAATGGCGATCCTAAATGTGATAATAAAAGATGTCAAGAGTGTGGGGTAAAATTTGAAGATCCTGAAGAAGCAGAAAAACATAAAATTATTGTACATAATAAAATGCATGATGGTGGGTCCAGTACTTACACGTGCATACAATGTCAGATATCATTTCCGAGCGAAACTATGATACAGCAGCATGTAACAAAAGAACATTTAGAAGCGTCAGGAAAAGGAGCCGTTGATACTTTGAGATGCCATTTATGTATATTCGAAGCAAATAGCCCTCTCCAATTGCAGAGTCATTTAATAGAGCATACGTTTGCCGGATGTGCTGCTCTCAATTGTTACATCTGTCAAGCTCTTTTCACTACGCCTATTGCTCTTCAGAATCATATGTTACAAGAACATGGCTTAAATGCACGACCTTACGATTGTTCGAAGTGTACCTCAAAGTTCTTTTTCAAAGCTGAATTAGATCATCATGTATTGATGTTTCATCGTATCGAAGAAAATTCTGCATTGCCTGAAACGGTAAAAGATATGTTAGAAACAAATAACCAAATTAATAATAGTGAGGATCGTAAGTTCGATGAAAATATTACGATAAAAGAAGAATTATTACAAGGAACCGAAGAGGAAGAAGAACAACAAGAAGGAGAAGAAGAGGAAGAAGAAGAGGAGGAAGAAGTTAATGTAGATGGACAAATTGAACAAGAAAAGTTAGATAAAGAAGAATCAGAGCAAAAAAGGACAACTTTGAAAATTGAAGTCAATAAACAGATAGAATCTGAAAAGGAAGAAACGTGA
Protein Sequence: MLFKGNSSRLELLIGKIQAHKEPSQEEPHKSKEALGTGSSSWHSEDGGPTSRRGGETPSSCATPTSASFPSEPEIDGEVGIGTDGNNPTAPYPCQFCDRTFPRLSYLKKHEQSHGDQMPYRCSWCSRLFKHKRSRDRHVKLHTGDRRYRCSHCEAAFSRSDHLKIHMKTHDTQKPYQCTACSRGYNTAAALTSHMQSHKKHHQGTSNNSNKLQDSDYGRRSVSSHSTSSPPVPSSPSPSLNLSLNPKNTLKAPLGTSCSASTTPILNSPLKLACMYCTRDSFSCMQQLQMHVHTMHQAILSGENLVVAPSPSRTTDSVVDCSRDKLLDRSDGISKDQEKKYEERSMEKDYKNTFTCYQCTMKFSSLATLRDHLISIHRTDAFGTSLIMCPLCGIPCNSAAAYAEHYVLQHCENRRVAPQNPQEYIDPKLNGVYDTKGMRLQKNREQQPMLEPADLTSKHIKSCESNYTSSTLLCGQCGAALKDFESFREHLARHLQADHRNEAARYLCPKCETSFQNREDMLAHLTKHYLGQISKEYACSACKKLYPHPDLLQRHLLDSHAHHLYRCALCRDTFDSRVAIQVHFAVKHSQECRIYRCNACTAPNNENSPGNAPGEGRSFFRSESEMANHVRNIHAPPAMANNSPIARSPASTPGMTVNSGPRCVFCGIYCGSELELQLHLASHSTSLYRCPICREGFAVEFLLDRHITQVHHAGEHQIINARNNPRENGRLHRHPRSQEEVKSQKRGRSPASSNNNSLNQRDNNNKRPNFGVSGGQQCELCERGEFANEAELQAHKKLAHASSKVPSKSSLSNVSMTCAYCGEVCRSRNELESHMRMQHTSSEPGGRHKCNICDEVCPSGAILAEHKLQKHCKIQLSDTCVVCRGNLTTEALFLEHVQRHSLENVDPQQRLDNSLPHLPAPCVVCRQTLISDLECRLHARHHLRTSTSSPNTSSSPSPKQKPLNPNCCLCLREFSTEDFVNLPPNHFSGGQSLKVCKSCYVRYSQGLPILSSPYEHARNINNKCERSWIKDKDLQWDGSGDRWDTDRGFKNEDRSINDQNGDPKCDNKRCQECGVKFEDPEEAEKHKIIVHNKMHDGGSSTYTCIQCQISFPSETMIQQHVTKEHLEASGKGAVDTLRCHLCIFEANSPLQLQSHLIEHTFAGCAALNCYICQALFTTPIALQNHMLQEHGLNARPYDCSKCTSKFFFKAELDHHVLMFHRIEENSALPETVKDMLETNNQINNSEDRKFDENITIKEELLQGTEEEEEQQEGEEEEEEEEEEVNVDGQIEQEKLDKEESEQKRTTLKIEVNKQIESEKEET

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01232578;
90% Identity: iTF_01515022;
80% Identity: -