Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.38 6.8e+02 1.0 0.1 23 43 103 123 85 134 0.59

2 7 0.00055 0.99 10.1 0.0 23 52 131 160 126 162 0.83

3 7 2.3 4.1e+03 -1.5 0.0 22 36 158 172 155 183 0.73

4 7 0.022 39 5.0 0.1 24 52 188 216 180 218 0.90

5 7 1 1.9e+03 -0.3 0.0 22 44 214 236 211 240 0.83

6 7 1.2e-05 0.022 15.4 0.0 21 45 241 265 237 272 0.87

7 7 0.0019 3.4 8.4 0.3 23 43 271 291 267 299 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.38	6.8e+02	1.0	0.1	23	43	103	123	85	134	0.59
2	7	0.00055	0.99	10.1	0.0	23	52	131	160	126	162	0.83
3	7	2.3	4.1e+03	-1.5	0.0	22	36	158	172	155	183	0.73
4	7	0.022	39	5.0	0.1	24	52	188	216	180	218	0.90
5	7	1	1.9e+03	-0.3	0.0	22	44	214	236	211	240	0.83
6	7	1.2e-05	0.022	15.4	0.0	21	45	241	265	237	272	0.87
7	7	0.0019	3.4	8.4	0.3	23	43	271	291	267	299	0.86

Coding Sequence: ATGGCAAGCGAATCACCATACATAAAACAGGAGATCCAAGAGGAGATCGTAGAAGAAAAAATGATAATCGAACCcgaaatttcatttattaaaatcgaaTGCGATACATTTGAGGAAGATGGCGATTCGTACAATATGGAAACAGTAAACAGTGAAGAGGACGAATGTGTAAATAGTGATGCAGAACCAAATAGTATCAAACAAGGCGATACTAATAGCAATACAAACAAACAATGGAACAATGTAGATGATAAAAGAACTAAAGTTAAAAGAAGTAGTGTTAAAAATGGCAGTAGTGCGGATAAGAAAAGCATCGtgtgtgatatttgtaaaaaatgctttgGTAACATAAACAGCCTGCGATCACATAACCTCATTCATTTGAATATGAGACCTTTCAAATGCGATATTTGCGAAAAATCGTTCAGACAATCAGGTATTTTAAAAAGACATAAACTAATTCATTCTGGTGATAAACCGCATGTTTGCGATGTTTGCAATAGAAGCTTTCGGTTACCAAGTATTTTAAATTCGCATCGGTTACTTCATACCGACGTGACACCATACCAATGTGAGATCTGCCAAAAATTTTTCACTCAACAAACGGCGCTAAAACTTCACATAAAACTGCACAGCGGTGACAAACCGCATAATTGCAAAGTTTGCGGAAAAAGTTTTAGATTAATGGGCGACTTGAAATCtcattttttaatacatacaggCGAAAAACCATTTAAATGTGATATCTGTGCCATGGAATTTAGACAGTCGAGTAATCTGAGAAGCCACCAGGTCATTCATACGGGACTTAAACCATTCGAGTGCAATATCTGTCATAAGACTTACGGACGATCATCGAATTTGAAACGGCATCGATTGAGTCACACGCGTAAAGGAATTTAA
Protein Sequence: MASESPYIKQEIQEEIVEEKMIIEPEISFIKIECDTFEEDGDSYNMETVNSEEDECVNSDAEPNSIKQGDTNSNTNKQWNNVDDKRTKVKRSSVKNGSSADKKSIVCDICKKCFGNINSLRSHNLIHLNMRPFKCDICEKSFRQSGILKRHKLIHSGDKPHVCDVCNRSFRLPSILNSHRLLHTDVTPYQCEICQKFFTQQTALKLHIKLHSGDKPHNCKVCGKSFRLMGDLKSHFLIHTGEKPFKCDICAMEFRQSSNLRSHQVIHTGLKPFECNICHKTYGRSSNLKRHRLSHTRKGI

Sequence clustering based on sequence similarity using MMseqs2